Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alex Jiao"'
Autor:
Kai-Chun Yang, MD, Astrid Breitbart, MD, Willem J. De Lange, PhD, Peter Hofsteen, PhD, Akiko Futakuchi-Tsuchida, BS, Joy Xu, MSE, Cody Schopf, BS, Maria V. Razumova, PhD, Alex Jiao, PhD, Robert Boucek, MD, Lil Pabon, PhD, Hans Reinecke, PhD, Deok-Ho Kim, PhD, J. Carter Ralphe, MD, Michael Regnier, PhD, Charles E. Murry, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 728-740 (2018)
Summary: A novel myosin heavy chain 7 mutation (E848G) identified in a familial cardiomyopathy was studied in patient-specific induced pluripotent stem cell–derived cardiomyocytes. The cardiomyopathic human induced pluripotent stem cell–derived c
Externí odkaz:
https://doaj.org/article/55e66573abed49ff8e6ea65cc4f0d1b0
Publikováno v:
PLoS Biology, Vol 18, Iss 10, p e3000883 (2020)
Humans are remarkably skilled at listening to one speaker out of an acoustic mixture of several speech sources. Two speakers are easily segregated, even without binaural cues, but the neural mechanisms underlying this ability are not well understood.
Externí odkaz:
https://doaj.org/article/c1f2f771b5cd4a0e8b19a25747d4ebc8
Autor:
Alex Jiao, Travis Moerk, Nicholas A. Geisse, Rajneesh Jha, Eli J Fine, Jesse Macadangdang, Hannele Ruohola-Baker, Bonnie J. Berry
Publikováno v:
The FASEB Journal. 35
Autor:
Hans Reinecke, Deok Ho Kim, Lil Pabon, Joy Xu, Kai Chun Yang, Akiko Futakuchi-Tsuchida, Michael Regnier, Maria V. Razumova, Peter Hofsteen, Charles E. Murry, J. Carter Ralphe, Cody Schopf, Alex Jiao, Astrid Breitbart, Robert J. Boucek, Willem J. de Lange
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 728-740 (2018)
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 728-740 (2018)
Visual Abstract
Highlights • Many cardiomyopathy families have genetic variants whose significance is unknown. We studied a novel (E848G) mutation in MYH7, a sarcomeric protein. • Patient-specific induced pluripotent stem cell–derived card
Highlights • Many cardiomyopathy families have genetic variants whose significance is unknown. We studied a novel (E848G) mutation in MYH7, a sarcomeric protein. • Patient-specific induced pluripotent stem cell–derived card
Autor:
Deok Ho Kim, Jinsung Kim, Charles E. Murry, Mikael Perla, Alec S.T. Smith, Nisa Penland, Alex Jiao, Charles Travis Moerk
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:1543-1551
Skeletal muscle has a well-organized tissue structure comprised of aligned myofibers and an encasing extracellular matrix (ECM) sheath or lamina, within which reside satellite cells. We hypothesize that the organization of skeletal muscle tissues in
Autor:
Alex Jiao, Elliot Fisher, Bonnie J. Berry, Kevin T. Gray, Samir Kharoufeh, Jason Silver, Nicholas A. Geisse
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:107027
Publikováno v:
PLoS Biology, Vol 18, Iss 10, p e3000883 (2020)
PLoS Biology
PLoS Biology
Humans are remarkably skilled at listening to one speaker out of an acoustic mixture of several speech sources. Two speakers are easily segregated, even without binaural cues, but the neural mechanisms underlying this ability are not well understood.
Publikováno v:
Acta Biomaterialia. 9:7691-7698
Poly(N-vinylcaprolactam) (PNVCL) is a thermoresponsive polymer known to be nontoxic, water soluble and biocompatible. Here, PNVCL homopolymer was successfully synthesized for the first time by use of a one-step vapor-phase process, termed initiated c
Autor:
Marketa Hnilova, Michael Regnier, Jonathan H. Tsui, Daniel Carson, Alec S.T. Smith, Alex Jiao, Candan Tamerler, Cameron L. Nemeth, Xiulan Yang, Charles E. Murry, Deok Ho Kim
Publikováno v:
ACS applied materialsinterfaces. 8(34)
Understanding the phenotypic development of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is a prerequisite to advancing regenerative cardiac therapy, disease modeling, and drug screening applications. Lack of consistent hiPS
Publikováno v:
Annals of Biomedical Engineering. 40:1339-1355
Polymers provide a versatile platform for mimicking various aspects of physiological extracellular matrix properties such as chemical composition, rigidity, and topography for use in cell and tissue engineering applications. In this review, we provid