Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alex Janse"'
Autor:
Ianthe A. E. M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Lennart Kester, Jan J. Molenaar, Jules Meijerink, Jarno Drost, Weng Chuan Peng, Hindrik H. D. Kerstens, Bastiaan B. J. Tops, Frank C. P. Holstege, Patrick Kemmeren, Jayne Y. Hehir-Kwa
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Gene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making requires high confidence and precision of detection. Recent developments
Externí odkaz:
https://doaj.org/article/046a29bb1ff74c6daf6fc9a89b986d88
Autor:
Hindrik HD Kerstens, Jayne Y Hehir-Kwa, Ellen van de Geer, Chris van Run, Shashi Badloe, Alex Janse, John Baker-Hernandez, Sam de Vos, Douwe van der Leest, Eugène TP Verwiel, Bastiaan BJ Tops, Patrick Kemmeren
Publikováno v:
BioMedInformatics, Vol 3, Iss 1, Pp 1-16 (2022)
The increase in speed, reliability, and cost-effectiveness of high-throughput sequencing has led to the widespread clinical application of genome (WGS), exome (WXS), and transcriptome analysis. WXS and RNA sequencing is now being implemented as the s
Externí odkaz:
https://doaj.org/article/7e0f70a6bdf94d63b74fb2d4b6687172
Autor:
Michael T Meister, Marian J A Groot Koerkamp, Terezinha de Souza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc van Tuil, Rutger R G Knops, Sheila Terwisscha van Scheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M van Noesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van de Wetering, Ruben van Boxtel, Jarno Drost, Frank C P Holstege
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp 1-23 (2022)
Abstract Rhabdomyosarcomas (RMS) are mesenchyme‐derived tumors and the most common childhood soft tissue sarcomas. Treatment is intense, with a nevertheless poor prognosis for high‐risk patients. Discovery of new therapies would benefit from addi
Externí odkaz:
https://doaj.org/article/bfe59c6efb18489cb65ad4d76f02464c
Autor:
Ianthe A.E.M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. Verwiel, Douwe F.M. van der Leest, Lennart Kester, Jan J. Molenaar, Jules Meijerink, Jarno Drost, Weng Chuan Peng, Hinri H.D. Kerstens, Bastiaan B.J. Tops, Frank C.P. Holstege, Patrick Kemmeren, Jayne Hehir-Kwa
BackgroundGene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making requires high confidence and precision of detection. Recent developments show RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a7f736e8e0879a371604c9ddae82a3d
https://doi.org/10.21203/rs.3.rs-1745535/v1
https://doi.org/10.21203/rs.3.rs-1745535/v1
Autor:
Frank C. P. Holstege, Jarno Drost, Ruben van Boxtel, Marc van de Wetering, Jan J. Molenaar, Patrick Kemmeren, Jayne Y. Hehir-Kwa, Bastiaan B. J. Tops, Max M. van Noesel, Johannes H. M. Merks, Uta Flucke, Laura S. Hiemcke-Jiwa, Sheila Terwisscha van Scheltinga, Rutger R. G. Knops, Marc van Tuil, Karin P. S. Langenberg, Selma Eising, M. Emmy M. Dolman, Alex Janse, Hinri H. D. Kerstens, Camilla Calandrini, Freek Manders, Jeff DeMartino, Mariël Brok, Ewa Frazer-Mendelewska, Willemijn B. Breunis, Terezinha de Souza, Marian J. A. Groot Koerkamp, Michael T. Meister
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40d6c1a1dd7c26ccd4397c1f88597b5e
https://doi.org/10.15252/rc.2022721694
https://doi.org/10.15252/rc.2022721694
Autor:
Ianthe A. E. M. van Belzen, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Sam de Vos, John Baker-Hernandez, Alissa Groenendijk, Ronald de Krijger, Hindrik H. D. Kerstens, Jarno Drost, Marry M. van den Heuvel-Eibrink, Bastiaan B. J. Tops, Frank C. P. Holstege, Patrick Kemmeren, Jayne Y. Hehir-Kwa
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4872
Chromosomal alterations have recurrently been identified in Wilms tumors (WTs) and some are associated with poor prognosis. Gain of 1q (1q+) is of special interest given its high prevalence and is currently actively studied for its prognostic value.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bcc6028ce343b995363499dcc81365
https://doi.org/10.3390/cancers14194872
https://doi.org/10.3390/cancers14194872