Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alex J. Wang"'
Autor:
Alex J. Wang, Allysa Allen, Marianna Sofman, Pierre Sphabmixay, Ece Yildiz, Linda G. Griffith
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 1, Pp n/a-n/a (2022)
In vitro models of human liver functions are used across a diverse range of applications in preclinical drug development and disease modeling, with particular increasing interest in models that capture facets of liver inflammatory status. This study
Externí odkaz:
https://doaj.org/article/fd6252c1f1ac403aa15a5eee999e2759
Autor:
Christine-Maria Horejs, Jean-Philippe St-Pierre, Juha R. M. Ojala, Joseph A. M. Steele, Patricia Barros da Silva, Angela Rynne-Vidal, Stephanie A. Maynard, Catherine S. Hansel, Clara Rodríguez-Fernández, Manuel M. Mazo, Amanda Y. F. You, Alex J. Wang, Thomas von Erlach, Karl Tryggvason, Manuel López-Cabrera, Molly M. Stevens
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Matrix metalloproteinase enzymes are widely known to contribute to the breakdown of tissues. Here, the authors utilise a biomaterial substrate functionalised with a laminin fragment to modulate the expression of these enzymes, subsequently controllin
Externí odkaz:
https://doaj.org/article/6f96d69568c34d5fb8957a8cd8f04a9a
Autor:
Alex J, Wang, Allysa, Allen, Marianna, Sofman, Pierre, Sphabmixay, Ece, Yildiz, Linda G, Griffith
Publikováno v:
Adv Nanobiomed Res
In vitro models of human liver functions are used across a diverse range of applications in preclinical drug development and disease modeling, with particular increasing interest in models that capture facets of liver inflammatory status. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a893477a7dacef61c76e95c9ef4d841
https://pubmed.ncbi.nlm.nih.gov/35872804
https://pubmed.ncbi.nlm.nih.gov/35872804
Publikováno v:
Journal of Pain & Palliative Care Pharmacotherapy. 35:38-42
Treatment of Central Pain Syndrome (CPS) is known to be extremely challenging. Current therapies are unsatisfactory as patients report only mild to moderate pain relief. We report a case of using ketamine as a patient-controlled analgesia (PCA) for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efe00dbeb621977f06049e79dd23c80
https://doi.org/10.1080/15360288.2020.1814480
https://doi.org/10.1080/15360288.2020.1814480
Autor:
Linda G. Griffith, Ece Yildiz, Pierre Sphabmixay, Allysa Allen, Alex J. Wang, Marianna Sofman
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 1, Pp n/a-n/a (2022)
In vitro models of human liver functions are used across a diverse range of applications in preclinical drug development and disease modeling, with particular increasing interest in models that capture facets of liver inflammatory status. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e8c9531786ee29feeddce9e0fca128
https://doi.org/10.1002/anbr.202100049
https://doi.org/10.1002/anbr.202100049
Autor:
Nicholas X. Fang, Paula T. Hammond, Linda G. Griffith, Howon Lee, Pierre Sphabmixay, Alex J. Wang, Micha Sam Brickman Raredon
Publikováno v:
Biofabrication. 13:045024
Microphysiological systems (MPS), comprising human cell cultured in formats that capture features of the three-dimensional (3D) microenvironments of native human organs under microperfusion, are promising tools for biomedical research. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530bce3881597c859e7d3e2682084ed6
https://doi.org/10.1088/1758-5090/ac23aa
https://doi.org/10.1088/1758-5090/ac23aa
Autor:
Douglas A. Lauffenburger, Forest M. White, Linda G. Griffith, Kasper Renggli, Manu P. Kumar, Daniel A. Rothenberg, Linda Stockdale, Elizabeth A. Gordon, Jorge Valdez, Alex J. Wang, Christi D. Cook, Alexander Brown, Caroline C. Ahrens
Publikováno v:
Elsevier
Methods to parse paracrine epithelial-stromal communication networks are a vital need in drug development, as disruption of these networks underlies diseases ranging from cancer to endometriosis. Here, we describe a modular, synthetic, and dissolvabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbfe4b06e37b8958cd21c2a404a9d76
https://doi.org/10.1016/j.biomaterials.2017.03.030
https://doi.org/10.1016/j.biomaterials.2017.03.030
Autor:
Linda G. Griffith, Alex J. Wang, Paula T. Hammond, Hongkun He, Caroline C. Ahrens, Wade Wang, Marianna Sofman
Publikováno v:
Biomacromolecules. 21(2)
Expanding the toolkit of modular and functional synthetic material systems for biomimetic extracellular matrices (ECMs) is needed for achieving more predictable and characterizable cell culture. In the present study, we engineered a synthetic hydroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6897ee5160d99081b46f5365752d849a
https://pubmed.ncbi.nlm.nih.gov/31846304
https://pubmed.ncbi.nlm.nih.gov/31846304
Autor:
Zarko V. Boskovic, Alex J. Wang, Bridget K. Wagner, Alykhan F. Shamji, Stuart L. Schreiber, Drew J. Adams, Andrew M. Stern, Jimmy R. Theriault
Publikováno v:
ACS Chemical Biology
Elevation of reactive oxygen species (ROS) levels has been observed in many cancer cells relative to nontransformed cells, and recent reports have suggested that small-molecule enhancers of ROS may selectively kill cancer cells in various in vitro an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a83efd658461eeb27ef55d2b0abe9bb
http://europepmc.org/articles/PMC3658551
http://europepmc.org/articles/PMC3658551
Autor:
Christine-Maria, Horejs, Jean-Philippe, St-Pierre, Juha R M, Ojala, Joseph A M, Steele, Patricia Barros, da Silva, Angela, Rynne-Vidal, Stephanie A, Maynard, Catherine S, Hansel, Clara, Rodríguez-Fernández, Manuel M, Mazo, Amanda Y F, You, Alex J, Wang, Thomas, von Erlach, Karl, Tryggvason, Manuel, López-Cabrera, Molly M, Stevens
Publikováno v:
Nature Communications
Matrix metalloproteinases (MMPs) contribute to the breakdown of tissue structures such as the basement membrane, promoting tissue fibrosis. Here we developed an electrospun membrane biofunctionalized with a fragment of the laminin β1-chain to modula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d52998d3eae2e801bb973f23ab0b599
https://pubmed.ncbi.nlm.nih.gov/28593951
https://pubmed.ncbi.nlm.nih.gov/28593951