Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Alex J. Levine"'
Publikováno v:
Frontiers in Physics, Vol 8 (2021)
Understanding force propagation through the fibrous extracellular matrix can elucidate how cells interact mechanically with their surrounding tissue. Presumably, due to elastic nonlinearities of the constituent filaments and their random connection t
Externí odkaz:
https://doaj.org/article/8fd76ecda5e141328cb6562b84d8ea15
Publikováno v:
Physical Review Research, Vol 3, Iss 2, p 023150 (2021)
The spontaneously oscillating hair bundle of sensory cells in the inner ear is an example of a stochastic, nonlinear oscillator driven by internal active processes. Moreover, this internal activity is state dependent in nature—it measures the curre
Externí odkaz:
https://doaj.org/article/0f8b05da7bb646638703555bb780d469
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 506-515 (2016)
We present here the calculation of the mean time to capture of a tethered ligand to the receptor. This calculation is then used to determine the shift in the partitioning between (1) free, (2) singly bound, and (3) doubly bound ligands in chemical eq
Externí odkaz:
https://doaj.org/article/ac51377005434eb5bb2b465a79376fe7
Publikováno v:
Physical Review E. 107
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience.
The preBötzinger Complex (preBötC) encodes inspiratory time as rhythmic bursts of activity underlying each breath. Spike synchronization throughout a sparsely connected preBötC microcircuit initiates bursts that ultimately drive the inspiratory mo
Autor:
Victor K. Lai, Mark Keating, Robert T. Tranquillo, Alicja Jagiełło, Billianne Schultz, Connie M. Wang, Greeshma Thrivikraman, Alexander Nelson, Sandra Johnson, Alex J. Levine, Elliot L. Botvinick
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 29
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 29
Despite the ubiquitous importance of cell contact guidance, the signal-inducing contact guidance of mammalian cells in an aligned fibril network has defied elucidation. This is due to multiple interdependent signals that an aligned fibril network pre
Autor:
Alex J. Levine, Valentin M. Slepukhin
Publikováno v:
Polymers
Volume 13
Issue 13
Polymers, Vol 13, Iss 2195, p 2195 (2021)
Volume 13
Issue 13
Polymers, Vol 13, Iss 2195, p 2195 (2021)
We examine the nonequilibrium production of topological defects -- braids -- in semiflexible filament bundles under cycles of compression and tension. During these cycles, the period of compression facilitates the thermally activated pair production
Publikováno v:
Physical Review Research. 3
The authors show that feedback-based control in active, nonequilibrium systems with steady-state oscillatory behavior breaks the equilibrium as well as fluctuation-dissipation relations.
Autor:
Valentin M. Slepukhin, Alex J. Levine
Publikováno v:
Physical review letters. 127(15)
We discuss the response of biopolymer filament bundles bound by transient cross-linkers to compressive loading. These systems admit a mechanical instability at stresses typically below that of traditional Euler buckling. In this instability, there is
Autor:
Wolfgang A. Wall, Elliot L. Botvinick, Qingda Hu, Valentin M. Slepukhin, Alex J. Levine, Maximilian J. Grill
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 15
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance A common structural motif for stress-bearing intracellular structures and tissues is a network of filament bundles. When observed in optical microscopy, these bundles often show localized bends—kinks—in their contour even though the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aae23e0400d1e2abe93afda460e918d
https://escholarship.org/uc/item/3gr4t3h7
https://escholarship.org/uc/item/3gr4t3h7