Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Alex J Rai"'
Autor:
Shaheer Khan, Jose Lutzky, Alexander N. Shoushtari, Joanne Jeter, Brian Marr, Thomas E. Olencki, Colleen M. Cebulla, Mohamed Abdel-Rahman, J. William Harbour, Naomi Sender, Alexandra Nesson, Shahnaz Singh-Kandah, Susana Hernandez, Jeanelle King, Manpreet S. Katari, Lyssa Dimapanat, Stephanie Izard, Grazia Ambrosini, Oliver Surriga, Alex J. Rai, Codruta Chiuzan, Gary K. Schwartz, Richard D. Carvajal
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionApproximately 40% of patients with uveal melanoma (UM) will develop metastatic disease. Tumors measuring at least 12mm in basal diameter with a class 2 signature, as defined by a widely used gene expression-profiling test, are associated
Externí odkaz:
https://doaj.org/article/6d9c9f02602b4cf392e58ac3bafdaab3
Publikováno v:
Human Pathology: Case Reports, Vol 25, Iss , Pp 200535- (2021)
Hermansky-Pudlak syndrome (HPS) is an autosomal recessive genetic disorder in which the proper function of lysosome-related organelles (LROS) is impaired due to mutation in one of several well-characterized genes, including, but not limited to: HPS1,
Externí odkaz:
https://doaj.org/article/c93da974deb24b949d9289c1d48cec4b
Autor:
Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Karenah E Rajasekaran, Tianhao Wang, Kang Bei, John J Rajasekaran, Inna Yaskin, Alex J Rai, Rok Seon Choung, Joseph A Murray
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242655 (2020)
BackgroundAntibody diagnostics play an important role in disease detection and can potentially aid in monitoring of the immune responses to see if an individual has developed immunity. Developing high throughput diagnostics which does not involve han
Externí odkaz:
https://doaj.org/article/ef816c3a6ef24d2ea77a97886cf30c42
Autor:
James H Nichols, Mahesheema Ali, John I Anetor, Li Sheng Chen, Yu Chen, Sean Collins, Saswati Das, Sridevi Devaraj, Lei Fu, Brad S Karon, Heba Kary, Robert D Nerenz, Alex J Rai, Zahra Shajani-Yi, Vinita Thakur, Sihe Wang, Hoi Ying Elsie Yu, Lindsey E Zamora
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:1202-1236
Background The AACC Academy revised the reproductive testing section of the Laboratory Medicine Practice Guidelines: Evidence-Based Practice for Point-of-Care Testing (POCT) published in 2007. Methods A panel of Academy members with expertise in POCT
Uveal melanoma is a rare melanoma subtype different from cutaneous melanoma, with high incidence of liver metastasis and poor prognosis. Cancer cell–derived extracellular vesicles have been shown to induce proinflammatory and prometastatic signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c77c535b8703c2d98fdb39c880d1b89
https://doi.org/10.1158/1541-7786.c.6545627.v1
https://doi.org/10.1158/1541-7786.c.6545627.v1
Supplementary Figure from Uveal Melanoma Exosomes Induce a Prometastatic Microenvironment through Macrophage Migration Inhibitory Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ecfc1825000220bae3faed4cbf52cc
https://doi.org/10.1158/1541-7786.22528145.v1
https://doi.org/10.1158/1541-7786.22528145.v1
Autor:
Serge Cremers, Alex Lyashchenko, Alex J. Rai, Joshua Hayden, Amitava Dasgupta, Demetra Tsapepas, Sumit Mohan
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 82:246-250
Monitoring tacrolimus trough concentrations is important for optimal immunosuppression in solid organ transplant recipients. Available assays generally correlate well with each other but little attention is given to patients in whom tacrolimus metabo
Publikováno v:
Molecular Cancer Research. 20:661-669
Uveal melanoma is a rare melanoma subtype different from cutaneous melanoma, with high incidence of liver metastasis and poor prognosis. Cancer cell–derived extracellular vesicles have been shown to induce proinflammatory and prometastatic signalin
Autor:
Jeremy Michelson, Shannon Rausser, Amanda Peng, Temmie Yu, Gabriel Sturm, Caroline Trumpff, Brett A. Kaufman, Alex J. Rai, Martin Picard
Circulating cell-free mitochondrial DNA (cf-mtDNA) is an emerging biomarker of psychobiological stress and disease which predicts mortality and is associated with various disease states. To evaluate the contribution of cf-mtDNA to health and disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fb2152b7b989d36d8a8d8c568cddc5
https://doi.org/10.1101/2023.01.04.522744
https://doi.org/10.1101/2023.01.04.522744
Publikováno v:
Cancer Research. 83:4977-4977
Glycosaminoglycans (GAGs), such as heparan sulfate and chondroitin sulfate, are an important component of the tumor microenvironment (TME). These carbohydrates are attached to proteoglycans at the surface of tumor cells and play a vital role in malig