Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Alex J Baertschi"'
Autor:
Luís Miguel Cardoso Dos Santos, Pascal Azar, Cécile Brun, Stéphane König, Angela Roatti, Alex J. Baertschi, Chiraz Chaabane, Marie-Luce Bochaton-Piallat
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract During atherosclerotic plaque formation, smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype. We previously isolated differentiated spindle-shaped (S) and dedifferentiated rhomboid (R
Externí odkaz:
https://doaj.org/article/fcbd53799a9543e1a1afb7cefdd58195
Autor:
Luís Miguel Cardoso Dos Santos, Pascal Azar, Cécile Brun, Stéphane König, Angela Roatti, Alex J Baertschi, Chiraz Chaabane, Marie-Luce Bochaton-Piallat
Background. During atherosclerotic plaque formation smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype We previously isolated differentiated spindle-shaped (S) and dedifferentiated rhomboid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23b95e14063a34219f8bc5cc3824a05b
https://doi.org/10.21203/rs.3.rs-1977590/v1
https://doi.org/10.21203/rs.3.rs-1977590/v1
The aim is to compare the activation of ATP-sensitive potassium channels (K(ATP) channels) in intact and metabolically impaired atrial and ventricular myocytes.The K(ATP) channel current is measured by whole cell and gramicidin-perforated patch clamp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29afc8feb48b39e3d3ae6ad811b328cb
http://doc.rero.ch/record/293422/files/57-2-468.pdf
http://doc.rero.ch/record/293422/files/57-2-468.pdf
Autor:
Marie-Luce Bochaton-Piallat, Véronique Raeis-Dauvé, Aldo Domenico Milano, Maddalena Tessari, Alex J. Baertschi, Giuseppe Faggian, Angela Roatti, Pierre Philip-Couderc
Publikováno v:
Journal of the American College of Cardiology. 59(4):390-396
Objectives: The aim of this study was to test whether adenosine triphosphate-sensitive K+ (KATP) channel expression relates to mechanical and hypoxic stress within the left human heart.Background: ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fbc89c66d2c17b48898b67971aac6c
Abstract 140: Nuclear Targeting Apelin Induces Phenotypic Transition of Vascular Smooth Muscle Cells
Autor:
Marie-Luce Bochaton-Piallat, Chiraz Chaabane, Cécile Brun, Stéphane König, Yves Audigier, Alex J Baertschi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Apelin, and its receptor APJ, are a peptidic system playing a crucial role in vascular diseases. However, the role of apelin in atherogenesis and smooth muscle cell (SMC) proliferation remains unclear. We isolated 2 distinct SMC phenotypes from porci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5674ca5eb91e4a627beb3bc46b173e08
https://doi.org/10.1161/atvb.35.suppl_1.140
https://doi.org/10.1161/atvb.35.suppl_1.140
Publikováno v:
AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 2001, 280 (3), pp.H1058-H1065. ⟨10.1152/ajpheart.2001.280.3.H1058⟩
AJP-Heart and Circulatory Physiology, American Physiological Society, 2001, 280 (3), pp.H1058-H1065. ⟨10.1152/ajpheart.2001.280.3.H1058⟩
Because the electrophysiological effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on the heart are little known, we studied the regulation of the atrial ATP-sensitive K+(KATP) current by PACAP on primary cultured neonatal rat atr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299daa5854eb8cd92eea4871801bdd2c
https://doi.org/10.1152/ajpheart.2001.280.3.h1058
https://doi.org/10.1152/ajpheart.2001.280.3.h1058
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 278:H493-H499
The role of endothelin (ET) receptors was tested in volume-stimulated atrial natriuretic factor (ANF) secretion in conscious rats. Mean ANF responses to slow infusions (3 × 3.3 ml/8 min) were dose dependently reduced ( P < 0.05) by bosentan (nonsele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af74f8e7003c5542f0c8eef309062ee
https://doi.org/10.1152/ajpheart.2000.278.2.h493
https://doi.org/10.1152/ajpheart.2000.278.2.h493
Publikováno v:
Journal of the Autonomic Nervous System. 71:85-95
The goal of the present study was to examine the effect of clonidine withdrawal on the neural control of blood pressure. Rats were treated for 7–13 days with clonidine via osmotic minipumps (200 μ g kg −1 day −1 , s.c.). Controls received sali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f321f49c91c6b1e820ec8ae56bc26f
https://doi.org/10.1016/s0165-1838(98)00065-4
https://doi.org/10.1016/s0165-1838(98)00065-4
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 271:H2339-H2345
Perfused hearts (n = 127) were exposed to acute hypoxia (10% O2 for 12 or 20 min) or left atrial stretch (increase in atrial pressure) in the presence or absence of 100 mumol/l ATP-sensitive potassium channel blocker (tolbutamide) or openers (pinacid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc21f43e55f127320439475279c0199d
https://doi.org/10.1152/ajpheart.1996.271.6.h2339
https://doi.org/10.1152/ajpheart.1996.271.6.h2339
Autor:
Alex J. Baertschi, Robert L. Chevalier, Dianne G Muchant, David C Belmonte, Barbara A. Thornhill, Richard A. Pence
Publikováno v:
Pediatric Research. 40:294-299
The neonate conserves sodium avidly, and sodium intake is normally limited to that present in maternal milk. To evaluate the role of atrial natriuretic peptide (ANP) in this adaptation, preweaned rat pups were artificially reared and fed a formula wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1aa4f7959b6d34513f6cb1ff13239a1
https://doi.org/10.1203/00006450-199608000-00017
https://doi.org/10.1203/00006450-199608000-00017