Výsledky vyhledávání - "Alex J, Harvey"

Progress Toward the Culture and Transformation of Chicken Blastodermal Cells

Autor: Gordon Speksnijder, Michael A. Morgan, Steven A. Jones, Youliang Wang, Carrie F. Brooks, Lyn K. Olliff, Chuck Foley, Alex J. Harvey

Publikováno v: STEM CELLS. 24:1638-1645

Chicken blastodermal cells can be cultured for short periods of time and retain the ability to contribute to somatic and germline tissues when injected into gamma-irradiated stage X embryos. Such a method has yet to yield a germline transgenic bird,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d16ce88d47606b1a1fd076ab208884e
https://doi.org/10.1634/stemcells.2005-0491

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Anti- and pro-apoptotic activities of baculovirus and Drosophila IAPs in an insect cell line

Autor: Hatem Soliman, Alex J. Harvey, Lois K. Miller, William J. Kaiser

Publikováno v: Cell Death & Differentiation. 4:733-744

The anti-apoptotic activities of two baculovirus IAPs, OpIAP and CpIAP, were directly compared with that of two Drosophila IAPs, DIAP1 and DIAP2, in the same insect cell line, SF-21 cells. Like OpIAP and CpIAP, DIAP1 inhibited actinomycin D-induced a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dbb5c8b0be2c72a8994a8a18e64e33
https://doi.org/10.1038/sj.cdd.4400294

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Biologically active human interferon alpha-2b produced in the egg white of transgenic hens

Autor: Jeffrey C, Rapp, Alex J, Harvey, Gordon L, Speksnijder, Wei, Hu, Robert, Ivarie

Publikováno v: Transgenic research. 12(5)

We have previously described the expression of a bacterial protein in the egg white of transgenic chickens using a replication-deficient retroviral vector. Here we report the expression of a glycosylated human protein, interferon alpha-2b (hIFN), in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1537c56e9336e76ef8f1a2f51ae75afd
https://pubmed.ncbi.nlm.nih.gov/14601655

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Expression of exogenous protein in the egg white of transgenic chickens

Autor: Larry R. Baugh, Alex J. Harvey, Gordon Speksnijder, Julie A. Morris, Robert Ivarie

Publikováno v: Nature biotechnology. 20(4)

Using a replication-deficient retroviral vector based on the avian leukosis virus (ALV), we inserted into the chicken genome a transgene encoding a secreted protein, beta-lactamase, under the control of the ubiquitous cytomegalovirus (CMV) promoter.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61b4b2473f277776183cf21abc94b74
https://pubmed.ncbi.nlm.nih.gov/11923848

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Inhibition of Reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs)

Autor: Domagoj Vucic, Lois K. Miller, Alex J. Harvey, William J. Kaiser

IAPs comprise a family of inhibitors of apoptosis found in viruses and animals. In vivo binding studies demonstrated that both baculovirus and Drosophila IAPs physically interact with an apoptosis-inducing protein of Drosophila , Reaper (RPR), throug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ad18b3b1a344f57bdf7eb1212e6613
https://europepmc.org/articles/PMC23336/

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Multiple initiation mechanisms adapt phage T4 DNA replication to physiological changes during T4's development

Autor: Michael E. Gruidl, Nancy Colowick, Alex J. Harvey, Gisela Mosig, Ardith Chang

Publikováno v: FEMS microbiology reviews. 17(1-2)

We summarize the evidence for multiple pathways to initiate phage T4 DNA replication. In any infecting chromosome, leading DNA strands can be primed from pre-replicative transcripts, independent of primase activity, at one of several origins. Within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4942a61c06c921037fa77eb009a0d6
https://pubmed.ncbi.nlm.nih.gov/7669352

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