Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alex Ilic"'
Publikováno v:
Viral Immunology. 19:722-733
Clinical myocarditis is a precursor to dilated cardiomyopathy and a principal cause of heart failure. Nearly 30% of all recently diagnosed cases of myocarditis are attributable to infection with coxsackie B virus (CBV), the most frequently associated
Publikováno v:
Clinical Immunology. 110:134-144
Epidemiological studies have associated coxsackie B virus (CBV) with the development of insulin-dependent diabetes mellitus (IDDM) in humans. Infections of genetically susceptible mice with CBV strain 4 (CB4) induce autoimmune diabetes. Herein, we de
Publikováno v:
Virology. 314(2):510-520
The induction of autoimmunity by viruses has been hypothesized to occur by a number of mechanisms. Coxsackievirus B4 (CB4) induces hyperglycemia in SJL mice resembling diabetes in humans. While virus is effectively cleared within 2 weeks, hyperglycem
Publikováno v:
Journal of Clinical Investigation. 109:79-87
Publikováno v:
Journal of Autoimmunity. 16:211-217
The induction of autoimmunity by viruses has been attributed to numerous mechanisms. Coxsackievirus B4 (CB4) induces insulin-dependent diabetes mellitus (IDDM) in mice resembling the final step of disease progression in humans. Following viral infect
Publikováno v:
Nature Medicine. 6:693-697
Cardiovascular disease is one of the leading causes of death worldwide, and has been associated with many environmental risk factors1. Recent evidence has indicated the involvement of pathogens such as viruses as causative agents, and specifically id
Publikováno v:
Journal of autoimmunity. 25(2)
Chronic myocarditis often progresses to dilated cardiomyopathy resulting in heart failure or cardiac transplantation. Viral infection is the most common cause of myocarditis and coxsackie B viruses (CBV) are the most frequently cited etiologic agents
Publikováno v:
Cell. 117(2)
During illness and stress, the immune system can suffer a considerable loss of T cells (lymphopenia). The remaining T cells undergo vigorous compensatory expansion, known as homeostatic proliferation, to reconstitute the immune system. Interestingly,
Publikováno v:
The Journal of clinical investigation. 109(1)
The induction of autoimmunity by viruses has been attributed to numerous mechanisms. In mice, coxsackievirus B4 (CB4) induces insulin-dependent diabetes mellitus (IDDM) resembling the final step of disease progression in humans. The immune response f
Publikováno v:
Clinical immunology (Orlando, Fla.). 100(2)
Insulin-dependent diabetes mellitus results from T-cell-mediated destruction of pancreatic islet beta cells. Both CD4 and CD8 T cells have been shown to be independently capable of beta cell destruction. However, the mechanism of beta cell destructio