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pro vyhledávání: '"Alex I. Käiväräinen"'
Autor:
Alex I. Käiväräinen
Molecular biology has now advanced to the point where it is no longer possible to give a complete review of the available data on the conformational features of proteins. New data keep streaming in, and there is obviously an urgent need for some sort
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
The functional model of enzymatic activity which will be presented is really a development of the association and dissociation mechanisms of specific complexes, such as the mechanism described in the preceding chapter. Kaivarainen (1979c) derived exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b4286bfbd36d5764417186320bba42
https://doi.org/10.1007/978-94-009-5197-6_7
https://doi.org/10.1007/978-94-009-5197-6_7
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
It is known that when synthetic polymers of sufficient molecular mass are added to protein solutions in high concentrations, the proteins may form aggregates or may even crystallize out. This is usually explained as an effect of the excluded volume p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0839364d38bf80f29a8c478389634b96
https://doi.org/10.1007/978-94-009-5197-6_8
https://doi.org/10.1007/978-94-009-5197-6_8
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
If the dynamic model of behavior of proteins in water is accepted, the system: protein + bound water must be considered as one single whole. The changes in the state of the water and macromolecular segments solvated by it are clearly interrelated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b692848cdb18b656d0b62ad8f83a3c4
https://doi.org/10.1007/978-94-009-5197-6_4
https://doi.org/10.1007/978-94-009-5197-6_4
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
In our discussion of the applications of the dynamic model as a description of the properties of biopolymers and their hydrate shells, we have not so far dealt with their functional significance. We shall now attempt to apply the fundamental assumpti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da34b980149662cd97026e00b91a960
https://doi.org/10.1007/978-94-009-5197-6_6
https://doi.org/10.1007/978-94-009-5197-6_6
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
Even the most general conception of the protein molecule — which is imagined as a homopolymer with a linear memory — necessarily involves its capability of fluctuation (Lifshits, 1968; Lifshits and Grosberg, 1973). Statistical analysis indicates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4978ef17e39c8eb327abed7e82b5846
https://doi.org/10.1007/978-94-009-5197-6_3
https://doi.org/10.1007/978-94-009-5197-6_3
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
We shall now consider, from the aspect of the dynamic model of behavior of proteins in water, the effect on proteins of agents which, when present in small doses, perturb the system protein+water as one whole without, however, impairing its native pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c0fc3a2440ad796e6c47954c34d7ef
https://doi.org/10.1007/978-94-009-5197-6_5
https://doi.org/10.1007/978-94-009-5197-6_5
Autor:
Alex I. Käiväräinen
Publikováno v:
Solvent-Dependent Flexibility of Proteins and Principles of Their Function ISBN: 9789401087988
That physicochemical factors affect biological evolution has been repeatedly confirmed and is now considered as certain (see, e.g., Shnol’, 1979). One such highly important factor is the ‘habitat’ of the systems undergoing evolution, whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3c4729d50b7c83b7993cd28c37c463
https://doi.org/10.1007/978-94-009-5197-6_1
https://doi.org/10.1007/978-94-009-5197-6_1