Výsledky vyhledávání - "Alex Hopkins"

Akademický článek

On pandemics and pivots: a COVID-19 reflection on envisioning the future of medical education

Autor: Heeyoung Han, Amy Clithero-Eridon, Manuel João Costa, Caitriona A. Dennis, J. Kevin Dorsey, Kulsoom Ghias, Alex Hopkins, Kauser Jabeen, Debra Klamen, Sophia Matos, John D. Mellinger, Harm Peters, Suzanne Pitama, C. Leslie Smith, Susan F. Smith, Boyung Suh, Sookyung Suh, Marko Zdravković

Publikováno v: Korean Journal of Medical Education, Vol 33, Iss 4, Pp 393-404 (2021)

The required adjustments precipitated by the coronavirus disease 2019 crisis have been challenging, but also represent a critical opportunity for the evolution and potential disruptive and constructive change of medical education. Given that the form

Externí odkaz: https://doaj.org/article/42df869976504b1ab1fae7127a4be978

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Akademický článek

Impacts of heart disease, depression and their combination on all-cause mortality in older people: a rural community-based cohort study in China

Autor: Zhi Hu, Ruoling Chen, Alex Hopkins, Weiju Zhou, M Justin Zaman, Xuguang (Grant) Tao, Amanda Rodney, Yuyou Yao, Zhongqiang Cao, Ying Ma, John J Copeland

Publikováno v: BMJ Open, Vol 10, Iss 12 (2020)

Objective To assess the impact of heart disease (HD) combined with depression on all-cause mortality in older people living in the community.Design A population-based cohort study.Participants We examined the data of 1429 participants aged ≥60 year

Externí odkaz: https://doaj.org/article/de700f4cf6ea4342b674fc9909a9e905

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Akademický článek

Association between pretreatment lymphocyte count and response to PD1 inhibitors in head and neck squamous cell carcinomas

Autor: Won Jin Ho, Mark Yarchoan, Alex Hopkins, Ranee Mehra, Stuart Grossman, Hyunseok Kang

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)

Abstract Background Low absolute lymphocyte count (ALC) has previously been established as a marker of poor prognosis in multiple cancer types. There is growing evidence that ALC may also be associated with response to immunotherapy. This study explo

Externí odkaz: https://doaj.org/article/511bdc0063a440fe9199f53477949b38

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Akademický článek

Brief electrical stimulation and synkinesis after facial nerve crush injury: a randomized prospective animal study

Autor: Adrian Mendez, Alex Hopkins, Vincent L. Biron, Hadi Seikaly, Lin Fu Zhu, David W. J. Côté

Publikováno v: Journal of Otolaryngology - Head and Neck Surgery, Vol 47, Iss 1, Pp 1-8 (2018)

Abstract Background Recent studies have examined the effects of brief electrical stimulation (BES) on nerve regeneration, with some suggesting that BES accelerates facial nerve recovery. However, the facial nerve outcome measurement in these studies

Externí odkaz: https://doaj.org/article/fc68e9a68f5d4e71882ffe00d48073bc

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Supplemental Data from FOXC1 Regulates FGFR1 Isoform Switching to Promote Invasion Following TGFβ-Induced EMT

Autor: Fred B. Berry, Mackenzie L. Coatham, Alex Hopkins

Supplemental Table 1 lists the primers used for qPCR analysis in this study. Supplemental Table 2 contains a list of RNA transcripts down regulated in the shFOXC1 cells compared to shEGFP cells. Genes selected for further analysis are presented in Fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082290a91fdc25a6cf505a0cb0b5370b
https://doi.org/10.1158/1541-7786.22511082.v1

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Abstract 1685: Overcoming acquired resistance to PROTAC degraders

Autor: Tongchen He, Caleb Cheng, Abhijit Parolia, Alex Hopkins, Yuanyuan Qiao, Lanbo Xiao, Arul Chinnaiyan

Publikováno v: Cancer Research. 83:1685-1685

Background: Proteolysis-targeting chimera (PROTAC) technology has been widely investigated for cancer treatment and there have been several PROTAC degrader-based drugs used for clinical trials in the past few years. PROTAC degraders are able to targe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22f16bd4067ca69f7bffd8576779e470
https://doi.org/10.1158/1538-7445.am2023-1685

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Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness

Autor: Yize Li, Tung-Shing M. Lih, Saravana M. Dhanasekaran, Rahul Mannan, Lijun Chen, Marcin Cieslik, Yige Wu, Rita Jiu-Hsien Lu, David J. Clark, Iga Kołodziejczak, Runyu Hong, Siqi Chen, Yanyan Zhao, Seema Chugh, Wagma Caravan, Nataly Naser Al Deen, Noshad Hosseini, Chelsea J. Newton, Karsten Krug, Yuanwei Xu, Kyung-Cho Cho, Yingwei Hu, Yuping Zhang, Chandan Kumar-Sinha, Weiping Ma, Anna Calinawan, Matthew A. Wyczalkowski, Michael C. Wendl, Yuefan Wang, Shenghao Guo, Cissy Zhang, Anne Le, Aniket Dagar, Alex Hopkins, Hanbyul Cho, Felipe da Veiga Leprevost, Xiaojun Jing, Guo Ci Teo, Wenke Liu, Melissa A. Reimers, Russell Pachynski, Alexander J. Lazar, Arul M. Chinnaiyan, Brian A. Van Tine, Bing Zhang, Karin D. Rodland, Gad Getz, D.R. Mani, Pei Wang, Feng Chen, Galen Hostetter, Mathangi Thiagarajan, W. Marston Linehan, David Fenyö, Scott D. Jewell, Gilbert S. Omenn, Rohit Mehra, Maciej Wiznerowicz, Ana I. Robles, Mehdi Mesri, Tara Hiltke, Eunkyung An, Henry Rodriguez, Daniel W. Chan, Christopher J. Ricketts, Alexey I. Nesvizhskii, Hui Zhang, Li Ding, Alicia Francis, Amanda G. Paulovich, Andrzej Antczak, Anthony Green, Antonio Colaprico, Ari Hakimi, Barb Pruetz, Barbara Hindenach, Birendra Kumar Yadav, Boris Reva, Brenda Fevrier-Sullivan, Brian J. Druker, Cezary Szczylik, Charles A. Goldthwaite, Chet Birger, Corbin D. Jones, Daniel C. Rohrer, Darlene Tansil, David Chesla, David Heiman, Elizabeth Duffy, Eri E. Schadt, Francesca Petralia, Gabriel Bromiński, Gabriela M. Quiroga-Garza, George D. Wilson, Ginny Xiaohe Li, Grace Zhao, Yi Hsiao, James Hsieh, Jan Lubiński, Jasmin Bavarva, Jasmine Huang, Jason Hafron, Jennifer Eschbacher, Jennifer Hon, Jesse Francis, John Freymann, Josh Vo, Joshua Wang, Justin Kirby, Kakhaber Zaalishvili, Karen A. Ketchum, Katherine A. Hoadley, Ki Sung Um, Liqun Qi, Marcin J. Domagalski, Matt Tobin, Maureen Dyer, Meenakshi Anurag, Melissa Borucki, Michael A. Gillette, Michael J. Birrer, Michael M. Ittmann, Michael H. Roehrl, Michael Schnaubelt, Michael Smith, Mina Fam, Nancy Roche, Negin Vatanian, Nicollette Maunganidze, Olga Potapova, Oxana V. Paklina, Pamela VanderKolk, Patricia Castro, Paweł Kurzawa, Pushpa Hariharan, Qin Li, Qing Kay Li, Rajiv Dhir, Ratna R. Thangudu, Rebecca Montgomery, Richard D. Smith, Sailaja Mareedu, Samuel H. Payne, Sandra Cerda, Sandra Cottingham, Sarah Haynes, Shankha Satpathy, Shannon Richey, Shilpi Singh, Shirley X. Tsang, Shuang Cai, Song Cao, Stacey Gabriel, Steven A. Carr, Tao Liu, Thomas Bauer, Toan Le, Xi S. Chen, Xu Zhang, Yvonne Shutack, Zhen Zhang

Publikováno v: Cancer Cell. 41:139-163.e17

Clear cell renal cell carcinomas (ccRCCs) represent ∼75% of RCC cases and account for most RCC-associated deaths. Inter- and intratumoral heterogeneity (ITH) results in varying prognosis and treatment outcomes. To obtain the most comprehensive prof

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4878f21a9513cdfa5b273d1fdbaef4e6
https://doi.org/10.1016/j.ccell.2022.12.001

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Association between socioeconomic status and incident stroke in China

Autor: Jindong Ni, Jie Tang, Ken Forthby, Weiju Zhou, Yulong Wang, Alex Hopkins, Yuesong Pan, Ruoling Chen, Duolao Wang, Xiangyan Chen, Eric J. Brunner, Angela Clifford

Publikováno v: Journal of Epidemiology and Community Health

BackgroundLittle is known about the impact of socioeconomic status (SES) on incidence of stroke in China. This study aimed to examine the association of SES, which was measured by different indicators, with incidence of stroke and gender differences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9fbc90fef6091baa63859b4a14ca0b

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Impacts of heart disease, depression and their combination on all-cause mortality in older people: a rural community-based cohort study in China

Autor: Xuguang Grant Tao, Weiju Zhou, Zhongqiang Cao, M Justin Zaman, Zhi Hu, Alex Hopkins, John J Copeland, Ying Ma, Ruoling Chen, Yuyou Yao, Amanda Rodney

Publikováno v: BMJ Open, Vol 10, Iss 12 (2020)
BMJ Open

ObjectiveTo assess the impact of heart disease (HD) combined with depression on all-cause mortality in older people living in the community.DesignA population-based cohort study.ParticipantsWe examined the data of 1429 participants aged ≥60 years r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca94f879ccbc3ef232ad4bbee848cb0
https://doi.org/10.1136/bmjopen-2020-038341

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Association between pretreatment lymphocyte count and response to PD1 inhibitors in head and neck squamous cell carcinomas

Autor: Stuart A. Grossman, Alex Hopkins, Hyunseok Kang, Won Jin Ho, Mark Yarchoan, Ranee Mehra

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)
Journal for Immunotherapy of Cancer
Ho, WJ; Yarchoan, M; Hopkins, A; Mehra, R; Grossman, S; & Kang, H. (2018). Association between pretreatment lymphocyte count and response to PD1 inhibitors in head and neck squamous cell carcinomas. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 6. doi: 10.1186/s40425-018-0395-x. UCSF: Retrieved from: http://www.escholarship.org/uc/item/8dg061x7

Background Low absolute lymphocyte count (ALC) has previously been established as a marker of poor prognosis in multiple cancer types. There is growing evidence that ALC may also be associated with response to immunotherapy. This study explores wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b74757ed484010d4c4acf542d56204b
https://doi.org/10.1186/s40425-018-0395-x

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