Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Alex Harscher"'
1
A new system for the treatment of retinal degeneration
Autor: André Banzhaf, Alex Harscher, Anuschirawan Hekmat, Guido Blaess, Walter-G. Dr. Wrobel, Andreas Möller, Jens Pätzold, Rainer Mohrlok, Carmen Eipper
Publikováno v: Biomedizinische Technik/Biomedical Engineering. 56:277-282
Recent clinical studies indicate that stimulation of the retina with tiny amounts of current can have a therapeutic effect on retinal diseases such as retinitis pigmentosa. We have therefore developed a preventive treatment system which stimulates th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ddce051ff605b30ca90cb626d0a574
https://doi.org/10.1515/bmt.2011.106
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2
Subretinal electronic chips allow blind patients to read letters and combine them to words
Autor: Johannes Koch, Akos Kusnyerik, Tobias Peters, Dorothea Besch, Helmut G. Sachs, Veit-Peter Gabel, Steffen Kibbel, A. Bruckmann, Karl Ulrich Bartz-Schmidt, H. Benav, Alfred Stett, Alex Harscher, Udo Greppmaier, Peter Szurman, Robert Wilke, Eberhart Zrenner, Florian Gekeler, Katarina Stingl, Barbara Wilhelm
Publikováno v: Proceedings of the Royal Society B: Biological Sciences
A light-sensitive, externally powered microchip was surgically implanted subretinally near the macular region of volunteers blind from hereditary retinal dystrophy. The implant contains an array of 1500 active microphotodiodes (‘chip’), each with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd3871f8aff7ffc40dffdc6817a2ed1
http://europepmc.org/articles/PMC3081743
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3
A CMOS Chip With Active Pixel Array and Specific Test Features for Subretinal Implantation
Autor: Steffen Kibbel, Naser Pour Aryan, Liu Liu, Juergen Wuenschmann, Michael Fischer, Alex Harscher, Albrecht Rothermel
Publikováno v: IEEE Journal of Solid-State Circuits. 44:290-300
This paper presents a CMOS imager chip that is aimed at subretinal implantation for partially restoring human vision. It has low supply voltage (plusmn 2 V) and all DC free terminals for long life wired operation. Stimulation voltage is increased to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::270760ab2598adfbdaebe8397316f8b3
https://doi.org/10.1109/jssc.2008.2007436
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4
Interference experiments with energy filtered electrons
Autor: Joachim Mayer, Hannes Lichte, Alex Harscher
Publikováno v: Ultramicroscopy. 69:201-209
Interference of purely inelastically scattered electrons in the Gaussian image plane of an energy-filtering TEM (EFTEM) provides a means to measure the localisation of a specific inelastic scattering process. Although, the initial degree of angular c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e8a2f487481b8d67e4792af12a01b7f
https://doi.org/10.1016/s0304-3991(97)00046-6
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5
Experimental study of amplitude and phase detection limits in electron holography
Autor: Hannes Lichte, Alex Harscher
Publikováno v: Ultramicroscopy. 64:57-66
The well-known advantages of electron holography are the availability of amplitude and phase of the electron wave and the resulting improvement of lateral resolution by correction of the coherent aberrations. The noise properties of the holographic m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc09e850d29456f46bd4afe5ba320edd
https://doi.org/10.1016/0304-3991(96)00019-8
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6
Interpretable resolution of 0.2 nm at 100 kV using electron holography
Autor: Alex Harscher, Hannes Lichte, Günter Lang
Publikováno v: Ultramicroscopy. 58:79-86
Knowledge of amplitude and phase of the image wave is fundamental for numerical correction of the wave aberration. Therefore, off-axis electron holography provides a technique that could substantially improve the point resolution of an electron micro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17919225d1d68e388cc275e5e14fa7df
https://doi.org/10.1016/0304-3991(94)00180-u
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8
Restoration of useful vision up to letter recognition capabilities using subretinal microphotodiodes
Autor: Steffen Kibbel, Udo Greppmaier, W. Wrobel, A. Bruckmann, Helmut G. Sachs, Tobias Peters, Alex Harscher, Alfred Stett, H. Benav, Dorothea Besch, Robert Wilke, Karl U. Bartz-Schmidt, Eberhart Zrenner, Florian Gekeler, Akos Kusnyerik, Katarina Stingl, Barbara Wilhelm
Publikováno v: 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.
Our group has developed a subretinal microphotodiode array for restoration of vision. In a clinical pilot study the array has been implanted in 11 patients suffering from photoreceptor degenerations. Here we present promising results from some of tho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f8bfea5d8b4ed5974ed5545e96a1da
https://doi.org/10.1109/iembs.2010.5627549
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9
Electronic subretinal implants allow blind retinitis pigmentosa patients to read letters and recognize the direction of fine stripe patterns
Autor: E. Zrenner, Florian Gekeler, Udo Greppmaier, H. Benav, Barbara Wilhelm, J. Koch, Robert Wilke, Helmut G. Sachs, Dorothea Besch, K. U. Bartz-Schmidt, Alex Harscher, K. Porubská
Publikováno v: Acta Ophthalmologica. 87
Purpose Restoration of letter reading and stripe pattern recognition in blind RP patients by placing subretinal implants transchoroidally near the macula, consisting of two arrays: 4x4 electrodes controlled retroauricularly via a subdermal line for d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40a2676b640ce3075cb081de4c4eb6e2
https://doi.org/10.1111/j.1755-3768.2009.3114.x
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10
Design and Performance of an improved active subretinal chip
Autor: Eberhart Zrenner, Steffen Kibbel, Albrecht Rothermel, Walter-G. Dr. Wrobel, Alex Harscher
Publikováno v: IFMBE Proceedings ISBN: 9783642038860
The aim of the subretinal implant is to restore visual perception in blind patients suffering from retinitis pigmentosa (RP) and - at a later stage - age-related macular degeneration (AMD). Electrical stimulation of the remaining retinal neurons can
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ac23d7890b59c57f4315ec70725ae9c
https://doi.org/10.1007/978-3-642-03887-7_53
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