Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Alex Gutterres, Taranto"'
Autor:
Rodrigo Michelini de Oliveira Thomasi, Thaiz Rodrigues Teixeira, Gabriela Francine Martins Lopes, Simony Carvalho Mendonça, Brendo Araujo Gomes, Suzana Guimarães Leitão, Tiago Alves de Oliveira, Sara Thamires Dias da Fonseca, Alex Gutterres Taranto, Jaqueline Maria Siqueira Ferreira, Luciana Alves Rodrigues dos Santos Lima, Ana Hortência Fonsêca Castro
Publikováno v:
Microbiology Research, Vol 15, Iss 2, Pp 582-597 (2024)
Zika virus (ZIKV) is involved in the etiology of serious nervous system pathologies. Currently, there are no specific and effective vaccines or antiviral drugs to prevent the diseases caused by ZIKV. This study aimed to assess the activity of flavono
Externí odkaz:
https://doaj.org/article/fb0ca4d4250843f4a76af185ba8b5e85
Autor:
Tiago Alves de Oliveira, Michel Pires da Silva, Eduardo Habib Bechelane Maia, Alisson Marques da Silva, Alex Gutterres Taranto
Publikováno v:
Drugs and Drug Candidates, Vol 2, Iss 2, Pp 311-334 (2023)
Drug discovery and repositioning are important processes for the pharmaceutical industry. These processes demand a high investment in resources and are time-consuming. Several strategies have been used to address this problem, including computer-aide
Externí odkaz:
https://doaj.org/article/7f2014f9c8064aa5874d18ddb619ac6c
Autor:
Géssica Oliveira Mendes, Moysés Fagundes de Araújo Neto, Deyse Brito Barbosa, Mayra Ramos do Bomfim, Lorena Silva Matos Andrade, Paulo Batista de Carvalho, Tiago Alves de Oliveira, Daniel Luciano Falkoski, Eduardo Habib Bechelane Maia, Marcelo Siqueira Valle, Laila Cristina Moreira Damázio, Alisson Marques da Silva, Alex Gutterres Taranto, Franco Henrique Andrade Leite
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1645 (2023)
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive loss of cognitive functions, and it is the most prevalent type of dementia worldwide, accounting for 60 to 70% of cases. The pathogenesis of AD seems to involve th
Externí odkaz:
https://doaj.org/article/1e4067c1685d40df87a093a2fee6cdc4
Autor:
Géssica Oliveira Mendes, Samuel Silva da Rocha Pita, Paulo Batista de Carvalho, Michel Pires da Silva, Alex Gutterres Taranto, Franco Henrique Andrade Leite
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 880 (2023)
Alzheimer’s Disease (AD) is a neurodegenerative condition characterized by progressive memory loss and other affected cognitive functions. Pharmacological therapy of AD relies on inhibitors of the enzymes acetylcholinesterase (AChE) and butyrylchol
Externí odkaz:
https://doaj.org/article/6c0d5eb7386544ac830fa9adc5d1a850
Autor:
Fernanda de Moura Alves, Jessica Correa Bezerra Bellei, Camila de Souza Barbosa, Caíque Lopes Duarte, Amanda Luisa da Fonseca, Ana Claudia de Souza Pinto, Felipe Oliveira Raimundo, Bárbara Albuquerque Carpinter, Ari Sérgio de Oliveira Lemos, Elaine Soares Coimbra, Alex Gutterres Taranto, Vinícius Novaes Rocha, Fernando de Pilla Varotti, Gustavo Henrique Ribeiro Viana, Kézia K. G. Scopel
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1529 (2022)
Malaria is an infectious disease widespread in underdeveloped tropical regions. The most severe form of infection is caused by Plasmodium falciparum, which can lead to development of cerebral malaria (CM) and is responsible for deaths and significant
Externí odkaz:
https://doaj.org/article/d1a5836d18ba416a8d881bce8fde5ae7
Autor:
Tiago Alves de Oliveira, Lucas Rolim Medaglia, Eduardo Habib Bechelane Maia, Letícia Cristina Assis, Paulo Batista de Carvalho, Alisson Marques da Silva, Alex Gutterres Taranto
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 132 (2022)
DNA is a molecular target for the treatment of several diseases, including cancer, but there are few docking methodologies exploring the interactions between nucleic acids with DNA intercalating agents. Different docking methodologies, such as AutoDo
Externí odkaz:
https://doaj.org/article/adfe93ce80514a20b6cc6c00e53c21ca
Autor:
Eduardo Habib Bechelane Maia, Letícia Cristina Assis, Tiago Alves de Oliveira, Alisson Marques da Silva, Alex Gutterres Taranto
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The drug development process is a major challenge in the pharmaceutical industry since it takes a substantial amount of time and money to move through all the phases of developing of a new drug. One extensively used method to minimize the cost and ti
Externí odkaz:
https://doaj.org/article/b15f411cbeb34b50bd1132d7f84ab0c5
Autor:
Leite, Géssica Oliveira Mendes, Samuel Silva da Rocha Pita, Paulo Batista de Carvalho, Michel Pires da Silva, Alex Gutterres Taranto, Franco Henrique Andrade
Publikováno v:
Pharmaceuticals; Volume 16; Issue 6; Pages: 880
Alzheimer’s Disease (AD) is a neurodegenerative condition characterized by progressive memory loss and other affected cognitive functions. Pharmacological therapy of AD relies on inhibitors of the enzymes acetylcholinesterase (AChE) and butyrylchol
Autor:
Mayra Ramos do Bomfim, Deyse Brito Barbosa, Paulo Batista de Carvalho, Alisson Marques da Silva, Tiago Alves de Oliveira, Alex Gutterres Taranto, Franco Henrique Andrade Leite
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-15
Alzheimer's disease (AD) is a neurodegenerative pathology responsible for 70% of dementia cases worldwide. Despite its relevance, the few drugs available for the treatment of this disease offer only symptomatic relief, with limited efficacy and serio
Autor:
Renata Rachide Nunes, Amanda Luisa da Fonseca, Ana Claudia de Souza Pinto, Eduardo Habib Bechelane Maia, Alisson Marques da Silva, Fernando de Pilla Varotti, Alex Gutterres Taranto
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 114, Iss 0 (2019)
BACKGROUND Owing to increased spending on pharmaceuticals since 2010, discussions about rising costs for the development of new medical technologies have been focused on the pharmaceutical industry. Computational techniques have been developed to red
Externí odkaz:
https://doaj.org/article/c972b0d5f52843f883102bbda6fba509