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of 4
pro vyhledávání: '"Alex Gibbs"'
CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis
Autor:
Huw J. Morgan, Elise Rees, Simone Lanfredini, Kate A. Powell, Jasmine Gore, Alex Gibbs, Charlotte Lovatt, Gemma E. Davies, Carlotta Olivero, Boris Y. Shorning, Giusy Tornillo, Alex Tonks, Richard Darley, Eddie C.Y. Wang, Girish K. Patel
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
The basis of immune evasion, a hallmark of cancer, can differ even when cancers arise from one cell type such as in the human skin keratinocyte carcinomas: basal and squamous cell carcinoma. Here we showed that the basal cell carcinoma tumor–initia
Externí odkaz:
https://doaj.org/article/ea703a273eba40cda8c0b9d20462893e
Autor:
Ronald A. Coro, S. M. Mizanoor Rahman, Robert Dizor, Renan Barbosa, Cesar Gonzalez, Tomias Scott, Alex Gibbs, Bradley Regez, Stephen McCrory
Publikováno v:
ICHMS
Robotic prosthetic hands or arms often do not apply appropriate force and pressure and also do not have appropriate tactile and proprioceptive feedbacks as accurately and precisely as a human, which make the prosthetic arms less user-friendly and inc
Autor:
Peter Giles, Mia R. F. Georgiou, Sarab Taha, Alex Gibbs, Neil P. Rodrigues, Ali Abdelfattah, Florian A. Siebzehnrubl, Dhruv Shah, Badi Alotaibi, Simone Brabletz, Lubaid Saleh, Leigh-anne Thomas, Marc P. Stemmler, Alhomidi Almotiri, Sarah Edkins, Hamed Ahmad A. Alzahrani, Thomas Brabletz, Ashleigh S. Boyd, Adelle Greene, Juan Bautista Menendez-Gonzalez, Amani Salem Alsayari
Publikováno v:
The Journal of Clinical Investigation
Zeb1, a zinc finger E-box binding homeobox epithelial-mesenchymal transition (EMT) transcription factor, confers properties of “stemness,” such as self-renewal, in cancer. Yet little is known about the function of Zeb1 in adult stem cells. Here,
Autor:
Alex Gibbs, Samantha Sinnadurai, Leigh-anne Thomas, Zhengke Wang, Alfonso Garcia-Valverde, Neil P. Rodrigues, Rhys G. Morgan, Allison Blair, Maria Konstantinou, Ashleigh S. Boyd, Magali Boyer, Juan Bautista Menendez-Gonzalez
Publikováno v:
Menendez-Gonzalez, J B, Sinnadurai, S, Gibbs, A, Thomas, L, Konstantinou, M, Garcia-Valverde, A, Boyer, M, Wang, Z, Boyd, A S, Blair, A, Morgan, R G & Rodrigues, N P 2019, ' Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells ', Scientific Reports, vol. 9, 12212 (2019) . https://doi.org/10.1038/s41598-019-48589-0
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
GATA2, a zinc finger transcription factor predominantly expressed in hematopoietic cells, acts as an essential regulator of hematopoietic stem cell generation, survival and functionality. Loss and gain of GATA2 expression has been implicated in myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed752adc01c3daba6e99fc29f36f8c76
https://hdl.handle.net/1983/0fc9de71-230b-42b8-abd9-5194ca97349c
https://hdl.handle.net/1983/0fc9de71-230b-42b8-abd9-5194ca97349c