Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alex G Taranto"'
Autor:
Fernanda A. Oliveira, Ana Claudia S. Pinto, Caique L. Duarte, Alex G. Taranto, Eder Lorenzato Junior, Cleydson Finotti Cordeiro, Diogo T. Carvalho, Fernando P. Varotti, Amanda L. Fonseca
Publikováno v:
BMC Chemistry, Vol 16, Iss 1, Pp 1-13 (2022)
Abstract N-acylhydrazones are considered privileged structures in medicinal chemistry, being part of antimicrobial compounds (for example). In this study we show the activity of N-acylhydrazone compounds, namely AH1, AH2, AH4, AH5 in in vitro tests a
Externí odkaz:
https://doaj.org/article/f3b3899391b14600960590dfc72d872a
Autor:
Deyse B. Barbosa, Mayra R. do Bomfim, Tiago A. de Oliveira, Alisson M. da Silva, Alex G. Taranto, Jorddy N. Cruz, Paulo B. de Carvalho, Joaquín M. Campos, Cleydson B. R. Santos, Franco H. A. Leite
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1657 (2023)
Alzheimer’s disease causes chronic neurodegeneration and is the leading cause of dementia in the world. The causes of this disease are not fully understood but seem to involve two essential cerebral pathways: cholinergic and amyloid. The simultaneo
Externí odkaz:
https://doaj.org/article/fdd4fbc549674dd0b53eb8d1d2cef958
Publikováno v:
ACS Omega, Vol 5, Iss 12, Pp 6628-6640 (2020)
Externí odkaz:
https://doaj.org/article/3a57c496b57d4ee6a5fc83758a9104c7
Autor:
Rodrigo C. O. Sanches, Sandeep Tiwari, Laís C. G. Ferreira, Flávio M. Oliveira, Marcelo D. Lopes, Maria J. F. Passos, Eduardo H. B. Maia, Alex G. Taranto, Rodrigo Kato, Vasco A. C. Azevedo, Debora O. Lopes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Schistosomiasis remains a serious health issue nowadays for an estimated one billion people in 79 countries around the world. Great efforts have been made to identify good vaccine candidates during the last decades, but only three molecules reached c
Externí odkaz:
https://doaj.org/article/d04b57ebd9454dd78bb70b6b847e1c9c
Autor:
Marco T. C. Pessôa, Silmara L. G. Alves, Alex G. Taranto, José A. F. P. Villar, Gustavo Blanco, Leandro A. Barbosa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 85-97 (2018)
Digoxin and other cardiotonic steroids (CTS) exert their effect by inhibiting Na,K-ATPase (NKA) activity. CTS bind to the various NKA isoforms that are expressed in different cell types, which gives CTS their narrow therapeutic index. We have synthes
Externí odkaz:
https://doaj.org/article/7e9231caa3524e22926499a8a6f0f46b
Autor:
Jullyana S.S. Quintans, Rosana S.S. Barreto, Waldecy de Lucca, Cristiane F. Villarreal, Carla M. Kaneto, Milena B.P. Soares, Alexsandro Branco, Jackson R.G.S. Almeida, Alex G. Taranto, Angelo R. Antoniolli, Rivelilson M. Freitas, Lucindo J. Quintans-Júnior
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 8303-8316 (2014)
Hecogenin is a steroidal sapogenin largely drawn from the plants of the genus Agave, commonly known as ‘sisal’, and is one of the important precursors used by the pharmaceutical industry for the synthesis of steroid hormones. Hecogenin acetate (H
Externí odkaz:
https://doaj.org/article/5a320f295bf84f52a8527bf3ecf809cb
Autor:
Rafaela S. Galante, Alex G. Taranto, Maria G.B. Koblitz, Aristóteles Góes-Neto, Carlos P. Pirovani, Júlio C.M. Cascardo, Sandra H. Cruz, Gonçalo A.G. Pereira, Sandra A. de Assis
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 84, Iss 2, Pp 469-486 (2012)
The enzyme chitinase from Moniliophthora perniciosa the causative agent of the witches' broom disease in Theobroma cacao, was partially purified with ammonium sulfate and filtration by Sephacryl S-200 using sodium phosphate as an extraction buffer. R
Externí odkaz:
https://doaj.org/article/b6cad0548eaa40b19995dc5a623adb74
Autor:
Amanda R. Sena, Gildomar L.V. Júnior, Aristóteles Góes Neto, Alex G. Taranto, Carlos P. Pirovani, Júlio C.M. Cascardo, Russolina B. Zingali, Marcos A. Bezerra, Sandra A. Assis
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 83, Iss 2, Pp 599-609 (2011)
The enzyme glucanase from Moniliophthora perniciosa was produced in liquid medium and purified from the culture supernatant. A multivariate statistical approach (Response Surface Methodology - RSM) was employed to evaluate the effect of variables, in
Externí odkaz:
https://doaj.org/article/b9c146e0181e405d96dad0307a2a6b2e
Autor:
Sayonarah C Rocha, Marco T C Pessoa, Luiza D R Neves, Silmara L G Alves, Luciana M Silva, Herica L Santos, Soraya M F Oliveira, Alex G Taranto, Moacyr Comar, Isabella V Gomes, Fabio V Santos, Natasha Paixão, Luis E M Quintas, François Noël, Antonio F Pereira, Ana C S C Tessis, Natalia L S Gomes, Otacilio C Moreira, Ruth Rincon-Heredia, Fernando P Varotti, Gustavo Blanco, Jose A F P Villar, Rubén G Contreras, Leandro A Barbosa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108776 (2014)
Cardiotonic steroids are used to treat heart failure and arrhythmia and have promising anticancer effects. The prototypic cardiotonic steroid ouabain may also be a hormone that modulates epithelial cell adhesion. Cardiotonic steroids consist of a ste
Externí odkaz:
https://doaj.org/article/be6b9f94d29e4b688e9429a2fc67ac6a
Autor:
Izabella Thaís, Silva, Jennifer, Munkert, Elke, Nolte, Naira Fernanda Zanchett, Schneider, Sayonarah Carvalho, Rocha, Ana Carolina Pacheco, Ramos, Wolfgang, Kreis, Fernão Castro, Braga, Rodrigo Maia, de Pádua, Alex G, Taranto, Vanessa, Cortes, Leandro Augusto, Barbosa, Sven, Wach, Helge, Taubert, Cláudia Maria Oliveira, Simões
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 107
Cardiac glycosides (CGs) are natural compounds used to treat congestive heart failure. They have garnered attention as a potential cancer treatment option, especially because they bind to Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::407d6328468e4bd814419384ec7d827c
https://pubmed.ncbi.nlm.nih.gov/30107342
https://pubmed.ncbi.nlm.nih.gov/30107342