Zobrazeno 1 - 10 of 151 pro vyhledávání: '"Alex F. C. Flores"'
1
Akademický článek
Synthesis, Structure, and Cyclocondensation of the 4,4,4-Trifluoro-3,3-dihydroxy-2-methyl-1-(thien-2-yl)-1-butanone with Hydroxylamine and Hydrazine
Autor: Alex F. C. Flores, Bruna P. Kuhn, Darlene C. Flores, Mariano A. Pereira, Tatiane L. Balliano, Givanildo S. da Silva
Publikováno v: Journal of Spectroscopy, Vol 2018 (2018)
The synthesis of 4,4,4-trifluoro-3,3-dihydroxy-2-methyl-1-(thien-2-yl)butan-1-one (3) through acylation of 1,1-dimethoxy-1-(thien-2-yl)propane (1) with trifluoroacetic anhydride and its reactions with hydroxylamine and hydrazine was investigated. X-r
Externí odkaz: https://doaj.org/article/76beb0431c8f4ea58635d71a5dfc0895
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2
Design, synthesis, and structure of alkyl 1H-pyrazolecarboxylates from a raspberry ketone methyl ether
Autor: Patrick T. Campos, Mayara Sandrielly Pereira Soares, Taís Barcelos Goulart, Francieli Moro Stefanello, Roberta Cargnelutti, Sidnei Moura, Alex F. C. Flores, Adriana Machado Das Neves
Publikováno v: Chemistry of Heterocyclic Compounds. 56:1314-1320
This paper reports a one-pot synthesis of 5-[2-(4-methoxyphenyl)ethyl]-1H-pyrazole-3-carboxylates via cyclocondensation of 1,1,1-trichloro-4-methoxy-6-(4-methoxyphenyl)hex-3-en-2-one with hydrazine hydrochloride in ROH (R = Me, Et, n-Pr, i-Pr, i-Bu,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fe6e34366464cfd9e87f6fa1a9bf90a
https://doi.org/10.1007/s10593-020-02816-z
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3
Efficient Synthesis and Antimicrobial Activities of Long Alkyl Chain Trifluoromethyl1H-pyrazol-1-(thio)carboxamides and Trifluoromethyl-1H-pyrazol-1-yl-thiazoles
Autor: Alex F. C. Flores, Debora L. de Mello, Darlene C. Flores, Sidnei Moura, Juliana L. Malavolta, Leonardo Quintana Soares Lopes, Roberto Christ Vianna Santos
Publikováno v: Journal of the Brazilian Chemical Society, Volume: 32, Issue: 4, Pages: 900-911, Published: 29 MAR 2021
Journal of the Brazilian Chemical Society v.32 n.4 2021
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
The synthesis of 3-alkyl-5-trifluoromethyl-1H-pyrazole-1-carboxamides, 3-alkyl5-trifluoromethyl-1H-pyrazole-1-thiocarboxamides, and 2-(3-alkyl-5-trifluoromethyl-1H-pyrazol1-yl)-thiazoles derivatives are reported. [3 + 2] cyclocondensations for a seri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5dafc2e37dcc1afa652265d6f077e50
https://doi.org/10.21577/0103-5053.20200241
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4
Synthesis of pyrazoline fatty chain derivatives and its effects on melanoma cells
Autor: Luiz Eduardo Maia Nery, Priscila Antiqueira-Santos, Ana Paula de Souza Votto, Luciana A. Piovesan, Alex F. C. Flores, Wystan K.O. Teixeira
Publikováno v: Bioorganicmedicinal chemistry letters. 41
Skin cancer is the most common type of cancer in Brazil, representing 30% of all cases. Among these, melanoma represents only 3% of malignant neoplasms; however, it is the most serious and has a high capacity for metastasis. For this reason, it is ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41a645db14feec1d8e7d7cdabee59b5
https://pubmed.ncbi.nlm.nih.gov/33775838
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5
An Acetal Acylation Methodology for Producing Diversity of Trihalomethyl-1,3-dielectrophiles and 1,2-Azole Derivatives
Autor: Leandro Marcon Frigo, Alex F. C. Flores, Darlene C. Flores, Lucas Pizzuti, Debora L. de Mello, Valéria Dias de Oliveira Bareño, Juliana L. Malavolta, Rogerio F. Blanco, Daiane Carvalho dos Departamento de Solos Santos
Publikováno v: Journal of the Brazilian Chemical Society v.31 n.2 2020
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 31, Issue: 2, Pages: 244-264, Published: 20 JAN 2020
A series of functionalized 1,1,1-trihalo-4-methoxy-3-alken-2-ones [CX3C(O)CR1=CROMe, where X = F or Cl; R = n-heptyl, n-octyl, n-nonyl, n-decyl, n-undecyl, n-tridecyl, (CH2)2CH=C(Me)2, (CH2)2Ph, (CH2)2-(4-HOC6H4), (CH2)2-(4-MeOC6H4), (CH2)2CO2Me, (CH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8ea4abe575deb2e2d34e2b23af7a06
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000200244
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6
Involvement of reactive oxygen species in the oleoylethanolamide effects and its pyrazonilic analogue in melanoma cells
Autor: Ana Paula de Souza Votto, Daiane S. dos Santos, Alex F. C. Flores, Luiz Eduardo Maia Nery, Marcelo Gonçalves Montes D'Oca, Luciana A. Piovesan, Priscila Antiqueira-Santos, Carolina R. L. Hack
Publikováno v: Medicinal Chemistry Research. 26:2727-2736
The search for more substances that effectively fight melanoma is extremely important, because of its aggressive nature. In this sense, the molecular hybridization is a promising strategy. The aim of this work is to evaluate whether the antiprolifera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23b126f80cf901b351f4990add79cbf2
https://doi.org/10.1007/s00044-017-1971-1
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7
Unexpected Formation of Bis(hydrazinecarboximidamide) via Ultrasound Promoted Rearrangement of Epoxy Ketone
Autor: Eliandro Faoro, Adriana do Carmo Capiotto, Alex F. C. Flores, Davi F. Back, Silvania Rizzi Brasil, Lucas Pizzuti
Publikováno v: Orbital: The Electronic Journal of Chemistry, Vol 9, Iss 3, Pp 204-209 (2017)
An efficient synthesis of aromatic pyrazoles via cyclocondensation of epoxy chalcones with hydrazine is reported. When aminoguanidine hydrochloride is the dinucleophilic specie the reaction leads to a mixture of amidino pyrazole and a minor amount (1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff517bc239056cae46a41b861bede3da
http://orbital.ufms.br/index.php/Chemistry/article/view/972
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8
Formation of a new copper(II) dimer through heterocyclic ligand ring opening reaction: Supramolecular features and magnetic properties
Autor: Jorge Luiz Pimentel Júnior, Vanessa Carratu Gervini, Bruna Lisboa Gonçalves, Juliano Rosa de Menezes Vicenti, Rafael Duarte, Alex F. C. Flores, Robson Ricardo da Silva, Adailton J. Bortoluzzi, Robert A. Burrow
Publikováno v: Journal of Molecular Structure. 1128:410-418
Two new compounds were synthesized and characterized in this work: the heterocycle (Z)-1-(4-(hydroxyimino)-3,5-dimethyl-1-(methylcarbamothioyl)-4,5-dihydro-1H-pyrazol-5-yl)-4-methylthiosemicarbazide and a copper(II) thiosemicarbazonato dimeric comple
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::176fb5b0d61660a7f010dcbeb4ff3247
https://doi.org/10.1016/j.molstruc.2016.09.014
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9
Synthesis of 2,2,2-trifluoroethyl 1H-pyrazole carboxylates: Insight into the mechanism of trichloromethyl group hydrolysis
Autor: Alex F. C. Flores, Sidnei Moura, Darlene C. Flores, Helena A. Gonçalves, Bruna A. Pereira, Wystan K.O. Teixeira
Publikováno v: Journal of Fluorine Chemistry. 187:40-45
This paper reports one-pot synthesis of 2,2,2-trifluoroethyl 1H -pyrazole-5(3)-carboxylates via cyclocondensation of 1,1,1-trichloro-4-alkoxy-3-alken-2-ones [Cl 3 CC(O)C(R 2 ) = C(R 1 )OMe, where R 1 = H, CH 3 , n -octyl, n -nonyl, n -decyl, n -undec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3177764b0bca709d6a0fd84dee5e99e7
https://doi.org/10.1016/j.jfluchem.2016.05.009
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10
Synthesis, Structure, and Cyclocondensation of the 4,4,4-Trifluoro-3,3-dihydroxy-2-methyl-1-(thien-2-yl)-1-butanone with Hydroxylamine and Hydrazine
Autor: Tatiane Luciano Balliano, Givanildo da Silva, Alex F. C. Flores, Darlene C. Flores, Mariano A. Pereira, Bruna P. Kuhn
Publikováno v: Journal of Spectroscopy, Vol 2018 (2018)
The synthesis of 4,4,4-trifluoro-3,3-dihydroxy-2-methyl-1-(thien-2-yl)butan-1-one (3) through acylation of 1,1-dimethoxy-1-(thien-2-yl)propane (1) with trifluoroacetic anhydride and its reactions with hydroxylamine and hydrazine was investigated. X-r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1479257f2317e895f57efecbde1dc1b8
https://doaj.org/article/76beb0431c8f4ea58635d71a5dfc0895
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