Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Alex F. Drake"'
Autor:
Alex F. Drake, Charlotte K. Hind, Richard T. Amison, David A. Phoenix, Alice C. Hodgson-Casson, Tam T. T. Bui, Giorgia Manzo, Clive P. Page, Philip M. Ferguson, Carolyn Lam, J. Mark Sutton, Blaze G O' Shaughnessy, Melanie Clifford, A. James Mason, Bethany J Weller, Christian D. Lorenz, Simon C. Pitchford, Maria Clarke, Rico C. H. Man, Jenny K.W. Lam, Katarzyna A Ciazynska, R. Andrew Atkinson
Publikováno v:
Communications Biology
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-01420-3⟩
Manzo, G, Hind, C K, Ferguson, P, Amison, R, Hodgson-Casson, A, Ciazynska, K, Weller, B, Clarke, M, Lam, C, Man, R, O'Shaughnessy, B, Clifford, M, Bui, T, Drake, A, Atkinson, A, Lam, J, Pitchford, S, Page, C, Phoenix, D, Lorenz, C, Sutton, J M & Mason, J 2020, ' A Pleurocidin Analogue with Greater Conformational Flexibility, Enhanced Antimicrobial Potency and in vivo Therapeutic Efficacy ', Communications Biology, vol. 3, no. 1, 697 . https://doi.org/10.1038/s42003-020-01420-3
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-01420-3⟩
Manzo, G, Hind, C K, Ferguson, P, Amison, R, Hodgson-Casson, A, Ciazynska, K, Weller, B, Clarke, M, Lam, C, Man, R, O'Shaughnessy, B, Clifford, M, Bui, T, Drake, A, Atkinson, A, Lam, J, Pitchford, S, Page, C, Phoenix, D, Lorenz, C, Sutton, J M & Mason, J 2020, ' A Pleurocidin Analogue with Greater Conformational Flexibility, Enhanced Antimicrobial Potency and in vivo Therapeutic Efficacy ', Communications Biology, vol. 3, no. 1, 697 . https://doi.org/10.1038/s42003-020-01420-3
Antimicrobial peptides (AMPs) are a potential alternative to classical antibiotics that are yet to achieve a therapeutic breakthrough for treatment of systemic infections. The antibacterial potency of pleurocidin, an AMP from Winter Flounder, is link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75d65adf0a69c4934578e53063e81e0
https://hal.archives-ouvertes.fr/hal-03030382
https://hal.archives-ouvertes.fr/hal-03030382
Autor:
Bruno Pagano, Abdullah Jama, Pierre Martinez, Ester Akanho, Tam T T Bui, Alex F Drake, Franca Fraternali, Penka V Nikolova
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76014 (2013)
The p53 family of genes and their protein products, namely, p53, p63 and p73, have over one billion years of evolutionary history. Advances in computational biology and genomics are enabling studies of the complexities of the molecular evolution of p
Externí odkaz:
https://doaj.org/article/0fbfafcb116544339582bdb2a4e197c4
Autor:
Sukhvinder S. Bansal, Charlotte K. Hind, Hind Ali, Christian D. Lorenz, David A. Phoenix, Alex F. Drake, Philip M. Ferguson, Melanie Clifford, Tam T. T. Bui, V. Benjamin Gustilo, Giorgia Manzo, A. James Mason, Mark J. Sutton, R. Andrew Atkinson
Publikováno v:
Scientific Reports
Manzo, G, Ferguson, P M, Hind, C K, Clifford, M, Gustilo, V B, Ali, H, Bansal, S, Bui, T, Drake, A F, Atkinson, R A, Sutton, J M, Lorenz, C, Phoenix, D & Mason, A J 2019, ' Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities ', Scientific Reports, vol. 9, no. 1, 10934 . https://doi.org/10.1038/s41598-019-47327-w
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-47327-w⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Manzo, G, Ferguson, P M, Hind, C K, Clifford, M, Gustilo, V B, Ali, H, Bansal, S, Bui, T, Drake, A F, Atkinson, R A, Sutton, J M, Lorenz, C, Phoenix, D & Mason, A J 2019, ' Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities ', Scientific Reports, vol. 9, no. 1, 10934 . https://doi.org/10.1038/s41598-019-47327-w
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-47327-w⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Frogs such as Rana temporaria and Litoria aurea secrete numerous closely related antimicrobial peptides (AMPs) as an effective chemical dermal defence. Damage or penetration of the bacterial plasma membrane is considered essential for AMP activity an
Autor:
Matthew Davy, Tam T. T. Bui, Philip M. Ferguson, Alex F. Drake, Justyna Kozlowska, A. James Mason, Sarah-Beth T. A. Amos, Christian D. Lorenz, Louic S. Vermeer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-4 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-4 (2018)
The interaction of antimicrobial peptides (AMPs) with the inner membrane of Gram-negative bacteria is a key determinant of their abilities to exert diverse bactericidal effects. Here we present a molecular level understanding of the initial target me
Autor:
V. Benjamin Gustilo, Tam T. T. Bui, Melanie Clifford, Charlotte K. Hind, Hind Ali, Mark J. Sutton, R. Andrew Atkinson, Philip M. Ferguson, David A. Phoenix, Christian D. Lorenz, Sukhvinder S. Bansal, Alex F. Drake, A. James Mason, Giorgia Manzo
Frogs such as Rana temporaria and Litoria aurea secrete numerous closely related antimicrobial peptides (AMPs) as an effective chemical dermal defence. Despite the high similarity in physical properties and preference for adopting secondary amphipath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4eca28445e365deaf1cf97d54d89f9
https://doi.org/10.1101/388967
https://doi.org/10.1101/388967
Autor:
Philip M. Ferguson, Tam T. T. Bui, Christian D. Lorenz, Alex F. Drake, Vicente B Gustilo, Giorgia Manzo, R. Andrew Atkinson, Hind Ali, Giovanna Batoni, David A. Phoenix, A. J. Mason
Antimicrobial peptides (AMPs) are a potential source of new molecules to counter the increase in antimicrobial resistant infections but a better understanding of their properties is required to understand their native function and for effective trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dafd616039c3c89fb9d9a8a5bd6dbac
https://doi.org/10.1101/312215
https://doi.org/10.1101/312215
Autor:
Frederick J. Warren, Paul G. Royall, Mireille Hassoun, Carole Elleman, Peter R. Ellis, Benjamin B. Perston, Alex F. Drake, Gary P. Martin, Rim Jawad
Publikováno v:
Molecular Pharmaceutics. 11:2224-2238
This article reports on the stereochemical aspects of the chemical stability of lactose solutions stored between 25 and 60 °C. The lactose used for the preparation of the aqueous solutions was α-lactose monohydrate with an anomer purity of 96% α a
Autor:
Silvia Goldoni, Molly M. Stevens, Franziska Bode, Marcelo A. da Silva, Alex F. Drake, Cécile A. Dreiss
Publikováno v:
Macromolecular Bioscience. 14:817-830
This work investigates the effect of combining physical and chemical gelation processes in a biopolymer blend: chitosan and tilapia fish gelatin. Chemical (C) gels are obtained by cross-linking with the microbial enzyme transglutaminase at 37 °C. Hy
Publikováno v:
Chirality. 25:288-293
The UV absorption and electronic circular dichroism (ECD) spectra of (R)- and (S)-nicotine and (S)-nornicotine in aqueous solution were measured to a significantly lower wavelength range than previously reported, allowing the identification of four p
Autor:
Vera Thoss, Simon J. Coles, Mohammad Nur-e-Alam, Ifat Parveen, Alex F. Drake, Mark Ian Fowler, Derren J. Heyes, Martina Lahmann, Rizgar Hassan Mohammad, Graham J. Tizzard
Publikováno v:
Mohammad, R H, Nur-E-Alam, M, Lahmann, M, Parveen, I, Tizzard, G J, Coles, S J, Fowler, M, Drake, A F, Heyes, D & Thoss, V 2016, ' Isolation and characterisation of 13 pterosins and pterosides from bracken (Pteridium aquilinum (L.) Kuhn) rhizome ', Phytochemistry, vol. 128, pp. 82-94 . https://doi.org/10.1016/j.phytochem.2016.05.001
Systematic phytochemical investigations of the underground rhizome of Pteridium aquilinum (L.) Kuhn (Dennstaedtiaceae) afforded thirty-five pterosins and pterosides. By detailed analysis of one- and two-dimensional nuclear magnetic resonance spectros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f294a1de80499767a9c5f07f9165e5
https://doi.org/10.1016/j.phytochem.2016.05.001
https://doi.org/10.1016/j.phytochem.2016.05.001