Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alex Eli Pottash"'
Autor:
Alex Eli Pottash, Daniel Levy, Anjana Jeyaram, Leo Kuo, Stephanie M. Kronstadt, Wei Chao, Steven M. Jay
Publikováno v:
Non-Coding RNA, Vol 8, Iss 5, p 71 (2022)
Extracellular vesicles (EVs) have emerged as promising therapeutic entities in part due to their potential to regulate multiple signaling pathways in target cells. This potential is derived from the broad array of constituent and/or cargo molecules a
Externí odkaz:
https://doaj.org/article/ffb4c65ba4504a89a24698d30b281c3e
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-13 (2019)
Abstract Broad translational success of RNA interference (RNAi) technology depends on the development of effective delivery approaches. To that end, researchers have developed a variety of strategies, including chemical modification of RNA, viral and
Externí odkaz:
https://doaj.org/article/da15bd8366b345c3b8863ecda5d36388
Autor:
Tanya Tschirhart, Eunkyoung Kim, Ryan McKay, Hana Ueda, Hsuan-Chen Wu, Alex Eli Pottash, Amin Zargar, Alejandro Negrete, Joseph Shiloach, Gregory F. Payne, William E. Bentley
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Synthetic biology offers the ability to explore new ways of manipulating gene expression and function. Here the authors demonstrate an electrogenetic device that allows control of transcription by an exogenous electrical signal.
Externí odkaz:
https://doaj.org/article/0dbb255cb7794f2994f754cbab9bd21f
Publikováno v:
BioTechniques, Vol 62, Iss 1, Pp 31-36 (2017)
Scientists often exploit the motility of peritrichously flagellated bacteria for various applications. A common alteration is modifying the frequency of mid-movement changes in direction, known as tumbles. Such differences in bacterial swimming patte
Externí odkaz:
https://doaj.org/article/ab1b9900994b4d5e902cad91e16002a2
Autor:
Alex Eli Pottash, Daniel Levy, Anjana Jeyaram, Leo Kuo, Stephanie M. Kronstadt, Wei Chao, Steven M. Jay
Extracellular vesicles (EVs) have emerged as promising therapeutic entities in part due to their potential to regulate multiple signaling pathways in target cells. This potential is derived from the broad array of constituent and/or cargo molecules a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bcd9fd3111de55bb10c97d64419e2b0
https://doi.org/10.1101/2022.07.13.499941
https://doi.org/10.1101/2022.07.13.499941
Publikováno v:
Adv Ther (Weinh)
Sepsis is a deadly condition lacking a specific treatment despite decades of research. This has prompted the exploration of new approaches, with extracellular vesicles (EVs) emerging as a focal area. EVs are nanosized, cell-derived particles that tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9e96421ae08a0fb5f382056f207046
https://pubmed.ncbi.nlm.nih.gov/34423113
https://pubmed.ncbi.nlm.nih.gov/34423113
Autor:
Steven M. Jay, Jinan M. Oubaid, John S. Schardt, Rena G. Lapidus, Alex Eli Pottash, Stanley Lipkowitz, Madeleine Noonan-Shueh, Sonya C. Williams, Arif Hussain
Publikováno v:
AAPS J
Expression of the receptor tyrosine kinase HER3 is negatively correlated with survival in ovarian cancer, and HER3 overexpression is associated with cancer progression and therapeutic resistance. Thus, improvements in HER3-targeted therapy could lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0b87ca65c295145ac5c94a19f693ad
https://pubmed.ncbi.nlm.nih.gov/30949858
https://pubmed.ncbi.nlm.nih.gov/30949858
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-13 (2019)
Journal of Biological Engineering
Journal of Biological Engineering
Broad translational success of RNA interference (RNAi) technology depends on the development of effective delivery approaches. To that end, researchers have developed a variety of strategies, including chemical modification of RNA, viral and non-vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94b545056e7fe5610abe35336d93199
https://pubmed.ncbi.nlm.nih.gov/30891095
https://pubmed.ncbi.nlm.nih.gov/30891095
Autor:
Gregory F. Payne, Alex Eli Pottash, David N. Quan, Ryan McKay, Steven M. Jay, William E. Bentley, Matthew Wook Chang, Monil Ghodasra, John C. March, Wu Shang, John S. Schardt
Publikováno v:
Bioengineering & Translational Medicine
For therapies targeting diseases of the gastrointestinal tract, we and others envision probiotic bacteria that synthesize and excrete biotherapeutics at disease sites. Toward this goal, we have engineered commensal E. coli that selectively synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7ebb25a89bbad722affff4529c3ce2
https://pubmed.ncbi.nlm.nih.gov/30377661
https://pubmed.ncbi.nlm.nih.gov/30377661
Autor:
William E. Bentley, Ryan McKay, Gregory F. Payne, Pricila Hauk, Wu Shang, Jessica L. Terrell, Hsuan-Chen Wu, Alex Eli Pottash
Publikováno v:
Biotechnology and bioengineering. 114(12)
Probiotics, whether taken as capsules or consumed in foods, have been regarded as safe for human use by regulatory agencies. Being living cells, they serve as "tunable" factories for the synthesis of a vast array of beneficial molecules. The idea of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fc67bbda82f2f4e850a514c213de37
https://pubmed.ncbi.nlm.nih.gov/28755474
https://pubmed.ncbi.nlm.nih.gov/28755474