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pro vyhledávání: '"Alex D. Eaton"'
Autor:
Michael A Pazos, Bernard B Lanter, Lael M Yonker, Alex D Eaton, Waheed Pirzai, Karsten Gronert, Joseph V Bonventre, Bryan P Hurley
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006548 (2017)
Excessive neutrophil infiltration of the lungs is a common contributor to immune-related pathology in many pulmonary disease states. In response to pathogenic infection, airway epithelial cells produce hepoxilin A3 (HXA3), initiating neutrophil trans
Externí odkaz:
https://doaj.org/article/af2c8f88c5164c6d8be84c7240e433b0
Autor:
Bernard B. Lanter, Alex D. Eaton, Bryan P. Hurley, Jason M. Roper, Cindi Zimmermann, Bryan Delaney
Publikováno v:
Food and Chemical Toxicology. 115:451-459
Recent studies suggest that human derived intestinal epithelial cells (IECs) cultured as polarized monolayers on Transwell® filters may respond differently when exposed to hazardous and non-hazardous proteins. This experimental platform was based on
Autor:
Bernard B. Lanter, Bryan Delaney, Alex D. Eaton, Cindi Zimmermann, Jason M. Roper, Bryan P. Hurley
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 132
Recent studies suggest human-derived intestinal epithelial cell (IEC) lines cultured as polarized monolayers on permeable Transwell® filters are effective at differentiating between hazardous and non-hazardous proteins following a single exposure. I
Autor:
Marc S. Harper, Raymond Layton, Waheed Pirzai, Bryan P. Hurley, Cindi Zimmermann, Bryan Delaney, Alex D. Eaton, Jason M. Roper, Gregory S. Ladics
Publikováno v:
Food and Chemical Toxicology. 92:75-87
Human intestinal epithelial cell lines (T84, Caco-2, and HCT-8) grown on permeable Transwell™ filters serve as models of the gastrointestinal barrier. In this study, this in vitro model system was evaluated for effectiveness at distinguishing betwe
Autor:
Lael M. Yonker, Alex D. Eaton, Silverio Al, Bryan P. Hurley, Frederick M. Ausubel, Rhianna M. Hibbler, Gutu Da, Eliana Drenkard
Publikováno v:
Journal of Visualized Experiments.
Pseudomonas aeruginosa is a phenotypically and genotypically diverse and adaptable Gram-negative bacterium ubiquitous in human environments. P. aeruginosa is able to form biofilms, develop antibiotic resistance, produce virulence factors, and rapidly
Autor:
Joseph V. Bonventre, Michael A. Pazos, Bryan P. Hurley, Waheed Pirzai, Alex D. Eaton, Bernard B. Lanter, Lael M. Yonker, Karsten Gronert
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 8, p e1006548 (2017)
PLoS Pathogens, Vol 13, Iss 8, p e1006548 (2017)
Excessive neutrophil infiltration of the lungs is a common contributor to immune-related pathology in many pulmonary disease states. In response to pathogenic infection, airway epithelial cells produce hepoxilin A3 (HXA3), initiating neutrophil trans
Autor:
Avira Som, Bryan P. Hurley, Hui Min Leung, Alex D. Eaton, Kengyeh K. Chu, Guillermo J. Tearney
Publikováno v:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XV.
The intestinal epithelial barrier provides protection from external threats that enter the digestive system and persist beyond passage through the stomach. The effects of toxic agents on the intestinal epithelial cell monolayer have not been fully ch
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 106
An experimental platform employing human derived intestinal epithelial cell (IEC) line monolayers grown on permeable Transwell® filters was previously investigated to differentiate between hazardous and innocuous proteins. This approach was effectiv
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 98
• Intractable proteins did not produce adverse effects toward human intestinal epithelial cell (IEC) monolayers.
Publikováno v:
The Journal of Immunology. 200:173.13-173.13
Background Numerous lung associated diseased states such as acute pneumonia and cystic fibrosis (CF) are associated with increased concentrations of IL8 and infiltration of neutrophils (PMNs) in the airspace. IL8 production by lung epithelial cells (