Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alex D. Connaty"'
Autor:
Jay F. Storz, Grant B. McClelland, Graham R. Scott, Alex D. Connaty, Daphne S. Lau, Sajeni Mahalingam, Nastashya Wall, Zachary A. Cheviron
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 312:R400-R411
The low O2experienced at high altitude is a significant challenge to effective aerobic locomotion, as it requires sustained tissue O2delivery in addition to the appropriate allocation of metabolic substrates. Here, we tested whether high- and low-alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec110831ea6f6d7eaa868b3a09bfa4b
https://doi.org/10.1152/ajpregu.00365.2016
https://doi.org/10.1152/ajpregu.00365.2016
Autor:
Morgan A. Wyatt, Chad W. Johnston, Yong Li, Alex D. Connaty, Michael A. Skinnider, Russell G. Kerr, Nathan A. Magarvey, Alyssa L. Grunwald
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 43:293-298
Natural products are a crucial source of antimicrobial agents, but reliance on low-resolution bioactivity-guided approaches has led to diminishing interest in discovery programmes. Here, we demonstrate that two in-house automated informatic platforms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45a1f26c2f6aec0cebb67892a8e126a
https://doi.org/10.1007/s10295-015-1675-9
https://doi.org/10.1007/s10295-015-1675-9
Autor:
Sajeni Mahalingam, Zachary A. Cheviron, Mikaela A. Lui, Catherine M. Ivy, Jay F. Storz, Alex D. Connaty, Graham R. Scott, Paras Patel, Grant B. McClelland
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 308:R779-R791
The hypoxic and cold environment at high altitudes requires that small mammals sustain high rates of O2transport for exercise and thermogenesis while facing a diminished O2availability. We used laboratory-born and -raised deer mice ( Peromyscus manic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20805bd66496ab1521a5e59b2d665832
https://doi.org/10.1152/ajpregu.00362.2014
https://doi.org/10.1152/ajpregu.00362.2014
Publikováno v:
Evolution. 68:48-62
In species that are distributed across steep environmental gradients, adaptive variation in physiological performance may be attributable to transcriptional plasticity in underlying regulatory networks. Here we report the results of common-garden exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d9048ef7d6249cce73b390196b76016
https://doi.org/10.1111/evo.12257
https://doi.org/10.1111/evo.12257
Publikováno v:
Evolution; international journal of organic evolution. 68(1)
In species that are distributed across steep environmental gradients, adaptive variation in physiological performance may be attributable to transcriptional plasticity in underlying regulatory networks. Here we report the results of common-garden exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba4c0d9d37fa87a8acfadf6bca14a947
https://pubmed.ncbi.nlm.nih.gov/24102503
https://pubmed.ncbi.nlm.nih.gov/24102503
Autor:
Grant B. McClelland, Alex D. Connaty, Zachary A. Cheviron, Jay F. Storz, Gwendolyn C. Bachman
In response to hypoxic stress, many animals compensate for a reduced cellular O 2 supply by suppressing total metabolism, thereby reducing O 2 demand. For small endotherms that are native to high-altitude environments, this is not always a viable str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2e0a704d357c48e8ed5540917f99a3
https://europepmc.org/articles/PMC3365185/
https://europepmc.org/articles/PMC3365185/
