Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alex Chauhan"'
Autor:
Alex Chauhan, Nilesh Pandey, Ajesh Desai, Nitin Raithatha, Purvi Patel, Yesha Choxi, Rutul Kapadia, Ronak Khandelwal, Neeraj Jain
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220330 (2019)
BackgroundCervicitis is one of the major health problems amongst women caused by infection of various pathogens including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV) as well as human papillomavirus (HPV), and pe
Externí odkaz:
https://doaj.org/article/31edc9a7dd2f47cca31f01c1014007bf
Publikováno v:
F1000Research, Vol 7 (2018)
Background: Toll-like receptor 9 (TLR9) plays a key role in the elimination of viral pathogens by recognising their CpG DNA. Polymorphisms in the TLR9 gene may influence their recognition and subsequent elimination. Therefore, the present study was d
Externí odkaz:
https://doaj.org/article/3e807a9fe3e94897a1e9f143c81c4267
Autor:
Alex Chauhan, Ashish Patel, Samir Patel, Umang Shah, Neeraj Jain, Nilesh Pandey, Mehul Patel, Sandip Patel
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1370-1385
Background: Many natural and synthetic flavonoids have been studied and documented by inhibiting aromatase enzymes for their anti-cancer activity against breast carcinoma. The aromatase enzyme is a possible target for the estrogen's positive breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14090bb3bd48a2fa534543230bc0d503
https://doi.org/10.2174/1871520621666210827104406
https://doi.org/10.2174/1871520621666210827104406
Publikováno v:
Biomarkers in Medicine. 15:1187-1198
The Toll-like receptors play an essential role in immunity through targeting the pathogen-associated molecular patterns. Nucleotide variations in TLR genes, especially single-nucleotide polymorphisms, have been shown to alter host immune susceptibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53225c362b55eca2c7ffd9e83917347
https://doi.org/10.2217/bmm-2021-0077
https://doi.org/10.2217/bmm-2021-0077
Autor:
Mrugesh J. Patel, Kaushal P. Patel, Neeraj Jain, Paranjay Parikh, Alex Chauhan, Nilesh Pandey, Jignesh B. Timaniya
Publikováno v:
RSC Advances. 11:27627-27644
A series of novel pyrazoline scaffolds from coumarin–carbazole chalcones were synthesized. We explored various acetyl, amide, and phenyl substituents at the N-1 position of the pyrazoline core. The synthesized compounds were characterized by FTIR,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31407c139fc522132ebc42d6417fe5a1
https://doi.org/10.1039/d1ra03970a
https://doi.org/10.1039/d1ra03970a
Publikováno v:
Molecular Diagnosis & Therapy. 22:683-702
Toll-like receptors (TLRs) are a type of pattern-recognition receptor (PRR) that are part of the innate immune system known to recognize pathogen-associated molecular patterns and thereby play a crucial role in host immune response. Among the various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15c531c588bad5d91b228ca03f47497
https://doi.org/10.1007/s40291-018-0361-9
https://doi.org/10.1007/s40291-018-0361-9
Publikováno v:
Meta Gene. 17:249-255
Background Toll-like receptors (TLRs) play a key role in pathogen detection and initiating inflammatory response. Several lines of evidence have suggested chronic inflammation as one of the major factors linked to carcinogenesis. Single nucleotide po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f290d4c9d7a6eedb3778da5d06328b4
https://doi.org/10.1016/j.mgene.2018.07.003
https://doi.org/10.1016/j.mgene.2018.07.003
Autor:
Purvi Patel, Neeraj Jain, Ronak Khandelwal, Yesha Choxi, Rutul Kapadia, Ajesh Desai, Nitin Raithatha, Nilesh Pandey, Alex Chauhan
Publikováno v:
Microbial Pathogenesis. 159:105149
Genetic polymorphism in pathogen recognition receptors tends to influence infection, disease susceptibility, and progression. We analyzed the association of TLR4 and TLR9 gene polymorphisms with multiple hrHPV infections and HPV16 copy number in cerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3215c19bc0259e94f3fb5b657aa10a
https://doi.org/10.1016/j.micpath.2021.105149
https://doi.org/10.1016/j.micpath.2021.105149
Autor:
Rutul Kapadia, Purvi Patel, Yesha Choxi, Ronak Khandelwal, Nilesh Pandey, Ajesh Desai, Nitin Raithatha, Neeraj Jain, Alex Chauhan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Single nucleotide polymorphisms (SNPs) in TLR genes may serve as a crucial marker for early susceptibility of various cancers including cervical cancer. The present study was therefore designed to ascertain the role of TLR4 and TLR9 SNPs and haplotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b615d3892105cc881582ee92aa7839fe
https://doi.org/10.1038/s41598-019-46077-z
https://doi.org/10.1038/s41598-019-46077-z
Autor:
Nitin Raithatha, Neeraj Jain, Purvi Patel, Yesha Choxi, Rutul Kapadia, Alex Chauhan, Nilesh Pandey, Ajesh Desai, Ronak Khandelwal
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports
Scientific Reports
Single nucleotide polymorphisms (SNPs) in TLR genes may serve as a crucial marker for early susceptibility of various cancers including cervical cancer. The present study was therefore designed to ascertain the role of TLR4 and TLR9 SNPs and haplotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c52d4186785ff51bcad822d1d56fa5
http://link.springer.com/article/10.1038/s41598-019-55122-w
http://link.springer.com/article/10.1038/s41598-019-55122-w