Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alex Cazes"'
Autor:
Valentina Boeva, Stéphanie Jouannet, Romain Daveau, Valérie Combaret, Cécile Pierre-Eugène, Alex Cazes, Caroline Louis-Brennetot, Gudrun Schleiermacher, Sandrine Ferrand, Gaëlle Pierron, Alban Lermine, Thomas Rio Frio, Virginie Raynal, Gilles Vassal, Emmanuel Barillot, Olivier Delattre, Isabelle Janoueix-Lerosey
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72182 (2013)
Neuroblastoma is a pediatric cancer of the peripheral nervous system in which structural chromosome aberrations are emblematic of aggressive tumors. In this study, we performed an in-depth analysis of somatic rearrangements in two neuroblastoma cell
Externí odkaz:
https://doaj.org/article/de594cc74d654ac9a384b971b7f9ca38
Autor:
Pierre Mazot, Alex Cazes, Florent Dingli, Joffrey Degoutin, Théano Irinopoulou, Marie-Claude Boutterin, Bérangère Lombard, Damarys Loew, Bengt Hallberg, Ruth Helen Palmer, Olivier Delattre, Isabelle Janoueix-Lerosey, Marc Vigny
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33581 (2012)
Recently, activating mutations of the full length ALK receptor, with two hot spots at positions F1174 and R1275, have been characterized in sporadic cases of neuroblastoma. Here, we report similar basal patterns of ALK phosphorylation between the neu
Externí odkaz:
https://doaj.org/article/9d6429e92bd6409f8569ebcb91d45e53
Autor:
Katleen De Preter, Frank Speleman, Jorge Vialard, Johannes H. Schulte, Jan Cools, Piotr Zabrocki, Tom Van Maerken, Alan Van Goethem, Nadine Van Roy, Ilse Van Den Wyngaert, David Camacho Trujillo, Junko Takita, Michael Porcu, Glenn M. Marchall, Chris Liang, Geneviève Laureys, Isabelle Janoueix-Lerosey, Jay Gibbons, Olivier Delattre, Sara De Brouwer, An De Bondt, Marilena De Mariano, Belamy B. Cheung, Alex Cazes, Daniel R. Carter, Els Janssens, Anneleen Beckers, Sven Lindner, Shana Claeys, Candy Kumps, Irina Lambertz
Supplemental data 9: Summary of Gene Set Enrichment analysis results performed on expression data upon ALK inhibition in 10 cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8ba2b9fbd5cfbaa48dbc06a331da43
https://doi.org/10.1158/1078-0432.22459751.v1
https://doi.org/10.1158/1078-0432.22459751.v1
Autor:
Andrew M. Lowy, Marco Gymnopoulos, Hervé Tiriac, Alexis A. Wascher, Eric Wong, Dawn Jaquish, Evangeline S. Mose, Edgar Esparza, Oscar Betancourt, Alex Cazes
Purpose:Pancreatic cancer is an aggressive disease associated with a poor 5-year overall survival. Most patients are ineligible for surgery due to late diagnosis and are treated primarily with chemotherapy with very limited success. Pancreatic cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556bc0a604563eb965278ad8ebc346b1
https://doi.org/10.1158/1078-0432.c.6530867
https://doi.org/10.1158/1078-0432.c.6530867
Autor:
Katleen De Preter, Frank Speleman, Jorge Vialard, Johannes H. Schulte, Jan Cools, Piotr Zabrocki, Tom Van Maerken, Alan Van Goethem, Nadine Van Roy, Ilse Van Den Wyngaert, David Camacho Trujillo, Junko Takita, Michael Porcu, Glenn M. Marchall, Chris Liang, Geneviève Laureys, Isabelle Janoueix-Lerosey, Jay Gibbons, Olivier Delattre, Sara De Brouwer, An De Bondt, Marilena De Mariano, Belamy B. Cheung, Alex Cazes, Daniel R. Carter, Els Janssens, Anneleen Beckers, Sven Lindner, Shana Claeys, Candy Kumps, Irina Lambertz
Supplemental data 13: Summary of Gene Set Enrichment analysis results obtained on expression profiling data of CLB-Ââ€�GA on different time points (10' - 30'- 60' - 2h - 4h - 6h) after pharmacological inhibition using TAE-Ââ€�684.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25178759ac101de20553303d661c8c67
https://doi.org/10.1158/1078-0432.22459757.v1
https://doi.org/10.1158/1078-0432.22459757.v1
Autor:
Katleen De Preter, Frank Speleman, Jorge Vialard, Johannes H. Schulte, Jan Cools, Piotr Zabrocki, Tom Van Maerken, Alan Van Goethem, Nadine Van Roy, Ilse Van Den Wyngaert, David Camacho Trujillo, Junko Takita, Michael Porcu, Glenn M. Marchall, Chris Liang, Geneviève Laureys, Isabelle Janoueix-Lerosey, Jay Gibbons, Olivier Delattre, Sara De Brouwer, An De Bondt, Marilena De Mariano, Belamy B. Cheung, Alex Cazes, Daniel R. Carter, Els Janssens, Anneleen Beckers, Sven Lindner, Shana Claeys, Candy Kumps, Irina Lambertz
Supplemental data 1: Cell line information: Summary of the characteristics of cell lines used in this study including origin, tumor type, ALK and MYCN status (wt = wild type, NA = non amplified, A = amplified). Supplemental data 2: GI50 concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3d207cd2c5d9d3ddc79d0dc2c9a918
https://doi.org/10.1158/1078-0432.22459748
https://doi.org/10.1158/1078-0432.22459748
Autor:
Andrew M. Lowy, Marco Gymnopoulos, Hervé Tiriac, Alexis A. Wascher, Eric Wong, Dawn Jaquish, Evangeline S. Mose, Edgar Esparza, Oscar Betancourt, Alex Cazes
MET expression in pancreatic cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d2163ee84448114b8db94c4cb12811
https://doi.org/10.1158/1078-0432.22482251.v1
https://doi.org/10.1158/1078-0432.22482251.v1
Autor:
Katleen De Preter, Frank Speleman, Jorge Vialard, Johannes H. Schulte, Jan Cools, Piotr Zabrocki, Tom Van Maerken, Alan Van Goethem, Nadine Van Roy, Ilse Van Den Wyngaert, David Camacho Trujillo, Junko Takita, Michael Porcu, Glenn M. Marchall, Chris Liang, Geneviève Laureys, Isabelle Janoueix-Lerosey, Jay Gibbons, Olivier Delattre, Sara De Brouwer, An De Bondt, Marilena De Mariano, Belamy B. Cheung, Alex Cazes, Daniel R. Carter, Els Janssens, Anneleen Beckers, Sven Lindner, Shana Claeys, Candy Kumps, Irina Lambertz
Supplemental data 5: Differential expression analysis upon ALK inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259ac911c3c0e63378435357663b5dc6
https://doi.org/10.1158/1078-0432.22459754.v1
https://doi.org/10.1158/1078-0432.22459754.v1
Autor:
Katleen De Preter, Frank Speleman, Jorge Vialard, Johannes H. Schulte, Jan Cools, Piotr Zabrocki, Tom Van Maerken, Alan Van Goethem, Nadine Van Roy, Ilse Van Den Wyngaert, David Camacho Trujillo, Junko Takita, Michael Porcu, Glenn M. Marchall, Chris Liang, Geneviève Laureys, Isabelle Janoueix-Lerosey, Jay Gibbons, Olivier Delattre, Sara De Brouwer, An De Bondt, Marilena De Mariano, Belamy B. Cheung, Alex Cazes, Daniel R. Carter, Els Janssens, Anneleen Beckers, Sven Lindner, Shana Claeys, Candy Kumps, Irina Lambertz
Purpose: Activating ALK mutations are present in almost 10% of primary neuroblastomas and mark patients for treatment with small-molecule ALK inhibitors in clinical trials. However, recent studies have shown that multiple mechanisms drive resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e9c231d90692706480e995eac2927b
https://doi.org/10.1158/1078-0432.c.6524297
https://doi.org/10.1158/1078-0432.c.6524297
Autor:
Isabelle Janoueix-Lerosey, Olivier Delattre, Marc Vigny, Damarys Loew, Emmanuel Barillot, Gaëlle Pierron, Sandrine Ferrand, Stéphanie Jouannet, Gudrun Schleiermacher, Valérie Combaret, Julie Cappo, Romain Daveau, Valentina Boeva, Bérangère Lombard, Florent Dingli, Pierre Mazot, Caroline Louis-Brennetot, Alex Cazes
PDF file - 110K, 2p amplicons in the CLB-Bar cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901a3c87dafee9ae4a08a9f1a70f1853
https://doi.org/10.1158/0008-5472.22397259.v1
https://doi.org/10.1158/0008-5472.22397259.v1