Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alex C. Szatmary"'
Publikováno v:
Molecular Biology of the Cell
Cells chemotaxing in decaying gradients of primary chemoattractants maintain their chemotactic response by releasing secondary chemoattractants. Steep, local gradients of secondary chemoattractants can be reached with molecules of higher hydrophobici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1603101d9506dc5e5f8d4c0e594245a7
https://doi.org/10.1091/mbc.e17-05-0298
https://doi.org/10.1091/mbc.e17-05-0298
Autor:
Alex C. Szatmary, Ralph Nossal
Publikováno v:
Journal of Theoretical Biology. 425:103-112
Chemotaxis, the motion of cells directed by a gradient of chemoattractant molecules, guides cells in immune response, development, wound healing, and cancer. Unfortunately, this process is difficult to distinguish from chemokinesis, i.e., stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650ec1d213e09f406ca8111c77839b73
https://doi.org/10.1016/j.jtbi.2017.05.014
https://doi.org/10.1016/j.jtbi.2017.05.014
Publikováno v:
RSC advances. 4(100)
Migration of cells along gradients of effector molecules, i.e., chemotaxis, is necessary in immune response and is involved in development and cancer metastasis. The experimental assessment of chemotaxis thus is of high interest. The agarose spot ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8c2e576fa07eada7cf36552fafad62
https://pubmed.ncbi.nlm.nih.gov/25530845
https://pubmed.ncbi.nlm.nih.gov/25530845
Autor:
Charles D. Eggleton, Alex C. Szatmary
Knowledge of the response of elastic capsules to imposed fluid flow is necessary for predicting deformation and motion of biological cells and synthetic capsules in microfluidic devices and in the microcirculation. Capsules have been studied in shear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cdca4a7942b568e5aad83398ce3a9e
Publikováno v:
ASME 2012 Summer Bioengineering Conference, Parts A and B.
Circulating white blood cells adhere to endothelium near an infection site; this occurs because infection causes ligands to be expressed on activated endothelium. Initially, a white blood cell rolls on the substrate, but eventually forms a firm adhes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5880beca2937502a3f916b0545e80201
https://doi.org/10.1115/sbc2012-80894
https://doi.org/10.1115/sbc2012-80894
Autor:
Charles D. Eggleton, Alex C. Szatmary
Publikováno v:
Biophysical Journal. 102(3)
Circulating leukocytes adhere to endothelium in venules near infection sites; this is one step in leukocyte migration to infection. A leukocyte first forms adhesions between its PSGL-1 receptors and P-selectin on activated endothelium, causing it to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656fe7f8597a43d20547fcf122d469bf
Publikováno v:
Physical review. E, Statistical, nonlinear, and soft matter physics. 85(4 Pt 1)
Optical stretchers can be used to quantify elastic and homeostatic properties of cells. Because they can apply forces to cells without requiring direct contact, they may noninvasively measure mechanical properties related to cell and membrane health.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff10358edf9a17bf88c690c0f8aec535
https://pubmed.ncbi.nlm.nih.gov/22680514
https://pubmed.ncbi.nlm.nih.gov/22680514
Publikováno v:
Optics Express
Current methods for predicting stress distribution on a cell surface due to optical trapping forces are based on a traditional ray optics scheme for fixed geometries. Cells are typically modeled as solid spheres as this facilitates optical force calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62ffbbbb7319567b01abb5e2a15c070
Autor:
Alex C. Szatmary
Publikováno v:
Biophysical Journal. 108:307a
In inflammation, endothelial cells release adhesion molecules that mediate rolling of neutrophils. While rolling, neutrophils activate to become capable of firmly adhering to endothelial cells; after this, they migrate through the blood vessel wall i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694bab88e278bdd47621e2d8d79b2360
https://doi.org/10.1016/j.bpj.2014.11.1668
https://doi.org/10.1016/j.bpj.2014.11.1668
Autor:
Alex C. Szatmary
Publikováno v:
Biophysical Journal. 106:789a
For a neutrophil to reach an infection site, it circulates through the blood, adheres to the blood vessel wall, initially rolling, then adhering firmly; finally, the neutrophil actively passes through the wall. The initial rolling of a neutrophil is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352557c1b7916cf82144609c5bd9ba58
https://doi.org/10.1016/j.bpj.2013.11.4326
https://doi.org/10.1016/j.bpj.2013.11.4326