Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alex C. Scibetta"'
Autor:
Xueqin Gao, Aiping Lu, Ying Tang, Johannes Schneppendahl, Andrea B. Liebowitz, Alex C. Scibetta, Elizabeth R. Morris, Haizi Cheng, Charles Huard, Sarah Amra, Bing Wang, Mary A. Hall, Walter R. Lowe, Johnny Huard
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-18 (2018)
Abstract Background Human muscle-derived stem cells (hMDSCs) have been shown to regenerate bone efficiently when they were transduced with Lenti-viral bone morphogenetic protein 2 (LBMP2). However, whether the age of hMDSCs and the animal host affect
Externí odkaz:
https://doaj.org/article/8f0630ab8801446dab770466b032643e
Autor:
Marc J. Philippon, Hajime Utsunomiya, Dandan Zhu, Sudheer Ravuri, Alex C. Scibetta, Xueqin Gao, Catherine A. Logan, Walter R. Lowe, Mika Talwar, Joseph J. Ruzbarsky, Justin W. Arner, Johnny Huard
Publikováno v:
The American journal of sports medicine. 49(9)
Background: A previous publication demonstrated that the oral intake of losartan promoted microfracture-mediated hyaline-like cartilage repair in osteochondral defects of a rabbit knee model. However, an intra-articular (IA) injection of losartan may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b166b02b5f26b54b17cdcbf12886ee1
https://pubmed.ncbi.nlm.nih.gov/34259597
https://pubmed.ncbi.nlm.nih.gov/34259597
Autor:
Chieh Tseng, Sudheer Ravuri, Haiying Pan, Alex C. Scibetta, Ping Guo, Ling Zhong, Matthieu Huard, Johnny Huard, Aiping Lu, Krishna M. Sinha, Yan Cui, Fan Yang
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(3)
The decline of muscle regenerative potential with age has been attributed to a diminished responsiveness of muscle progenitor cells (MPCs). Heterochronic parabiosis has been used as a model to study the effects of aging on stem cells and their niches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b9cc989b2fd50e2fd5dee835948163
https://pubmed.ncbi.nlm.nih.gov/34137458
https://pubmed.ncbi.nlm.nih.gov/34137458
Autor:
Johnny Huard, Hajime Utsunomiya, Marc J. Philippon, Zhenhan Deng, Tamara Alliston, Xueqin Gao, Sudheer Ravuri, Gilberto Yoshinobu Nakama, Alex C. Scibetta, Walter R. Lowe, Julia L Goldman, Haizi Cheng, William G. Rodkey
Publikováno v:
The American journal of sports medicine. 48(4)
Background: Microfracture or bone marrow stimulation (BMS) is often the first choice for clinical treatment of cartilage injuries; however, fibrocartilage, not pure hyaline cartilage, has been reported because of the development of fibrosis in the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81311937a7c8cb03fdb9575937b2d830
https://pubmed.ncbi.nlm.nih.gov/32027515
https://pubmed.ncbi.nlm.nih.gov/32027515
Autor:
Heather Nick, Nam Vo, Enrico Pola, Ryan D. O’Kelly, Aditi U. Gurkar, Laura J. Niedernhofer, Lana Corbo, Xuesen Li, Johnny Huard, Sara J. McGowan, Jing Zhao, Smitha P.S. Pilla, Paul D. Robbins, Christina Bukata, Lei Zhang, Aiping Lu, Matthew J. Yousefzadeh, Hongshuai Li, Luise Angelini, Alex C. Scibetta, Debora Colangelo, Warren C. Ladiges, Tokio Sano, Yingchao Han
Publikováno v:
Aging (Albany NY)
NF-κB is a transcription factor activated in response to inflammatory, genotoxic and oxidative stress and important for driving senescence and aging. Ataxia-telangiectasia mutated (ATM) kinase, a core component of DNA damage response signaling, acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477e00d470cc3399b1c41bfe8585e110
http://hdl.handle.net/10807/154814
http://hdl.handle.net/10807/154814
Autor:
Haizi Cheng, Zhenhan Deng, Alex C. Scibetta, Hajime Utsunomiya, Johnny Huard, Marc J. Philippon, Sudheer Ravuri, Xueqin Gao, Tamara Alliston, Walter R. Lowe
Publikováno v:
Orthopaedic Journal of Sports Medicine
Objectives: Application of growth factors for cartilage injury has been considered in recent studies; however, the effect of blocking detrimental growth factors for cartilage injury has not been well described. It is known that transforming growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3f8b440b9e9ad172985c683a0e5b85
http://europepmc.org/articles/PMC6664478
http://europepmc.org/articles/PMC6664478
Autor:
Alex C. Scibetta, Lucca Lacheta, Hunter W. Storaci, Nicole Anderson, Burak Altintas, Peter J. Millett
Publikováno v:
Arthroscopy : the journal of arthroscopicrelated surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 35(10)
The purpose of this study was to evaluate biomechanical and histopathological results of a retrieved acellular human dermal allograft (AHDA) after superior capsule reconstruction (SCR). A 67-year-old man with pseudoparalysis was treated with SCR for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a44081fdb68c454d42befd8ef8b4d9a
https://pubmed.ncbi.nlm.nih.gov/31604518
https://pubmed.ncbi.nlm.nih.gov/31604518
Autor:
Andrea B. Liebowitz, Haizi Cheng, Johannes Schneppendahl, Johnny Huard, Aiping Lu, Xueqin Gao, Charles Huard, Elizabeth R. Morris, Sarah Amra, Walter R. Lowe, Ying Tang, Mary A. Hall, Alex C. Scibetta, Bing Wang
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-18 (2018)
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-18 (2018)
Background Human muscle-derived stem cells (hMDSCs) have been shown to regenerate bone efficiently when they were transduced with Lenti-viral bone morphogenetic protein 2 (LBMP2). However, whether the age of hMDSCs and the animal host affect the bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d465da3fc03606ce310572f703d6969
http://europepmc.org/articles/PMC6249775
http://europepmc.org/articles/PMC6249775
Autor:
Xueqin Gao, Andrea B. Liebowitz, Elizabeth R. Morris, Alex C. Scibetta, Johnny Huard, Marc J. Philippon, Aiping Lu
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 37(6)
People of all backgrounds are susceptible to bone and cartilage damage, and these injuries can be debilitating. Current treatments for bone and cartilage injuries are less than optimal, and we are interested in developing new approaches to treat thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a28cf5da84c6bacca13f96dba574566
https://pubmed.ncbi.nlm.nih.gov/30667562
https://pubmed.ncbi.nlm.nih.gov/30667562
Autor:
Johnny Huard, Elizabeth R. Morris, Mark S. Schickendantz, Jorge Chahla, Alex C. Scibetta, Salvatore J. Frangiamore, Robert F. LaPrade, Thomas R. Hackett, Matthew T. Provencher, Gilbert Moatshe, David M. Civitarese
Publikováno v:
Orthopaedic Journal of Sports Medicine
Background:Vascular-derived progenitor and endothelial cell populations (CD31, CD34, CD146) are capable of multipotent differentiation at the site of injured ligamentous tissue to aid in the intrinsic healing response. Proximal ulnar collateral ligam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9773fbe2635ec118fecd264f50a1d662
http://hdl.handle.net/11250/2595654
http://hdl.handle.net/11250/2595654