Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Alex C. McLaren"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 879 (2024)
Effective treatment of postoperative pain lasting for multiple days without opioids is an important clinical need. We previously reported analgesia lasting up to 96 h in a porcine soft tissue model of postoperative pain using SBG004, an extended-rele
Externí odkaz:
https://doaj.org/article/42a856c6b61f4bdca8f939502c472777
Publikováno v:
Pain medicine (Malden, Mass.).
Objective A local anesthetic that provides analgesia lasting at least three days could significantly improve postoperative pain management. This study evaluated the analgesic efficacy and safety of an extended-release formulation of bupivacaine based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fccd27a7983b0bd82b6b2b3e351eee1
https://pubmed.ncbi.nlm.nih.gov/35944219
https://pubmed.ncbi.nlm.nih.gov/35944219
Autor:
Michelle Ghert, Thomas W. Bauer, Bryan D. Springer, Parham Sendi, Hyonmin Choe, John L. Daiss, Kordo Saeed, Paul Stoodley, Débora C. Coraça-Huber, Thomas P. Sculco, Noreen J. Hickok, Barry D. Brause, Alex C. McLaren, Edward M. Schwarz, William V. Arnold, Antonia F. Chen, Javad Parvizi, Kohei Nishitani
Publikováno v:
J Orthop Res
Musculoskeletal infections (MSKIs) remain a major health burden in orthopaedics. Bacterial toxins are foundational to pathogenesis in MSKI, but poorly understood by the community of providers that care for patients with MSKI, inducing an internationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed219afcae5751ce303b1a9de175b3d
https://doi.org/10.1002/jor.24683
https://doi.org/10.1002/jor.24683
Autor:
Shannon Huey Hilton, Mark A. Hayes, Claire Victoria Crowther, Alex C. McLaren, Jared P. Smithers
Publikováno v:
The Analyst. 145:2904-2914
Differentiating bacteria strains using biophysical forces has been the focus of recent studies using dielectrophoresis (DEP). The refinement of these studies has created high-resolution separations such that very subtle properties of the cells are en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f71e3330414d0b5763c3ab8fb381a94
https://doi.org/10.1039/c9an01449g
https://doi.org/10.1039/c9an01449g
Publikováno v:
Comp Immunol Microbiol Infect Dis
The objective of this study was to evaluate local antimicrobial delivery from temperature-responsive hydrogels for preventing infection in a rat model of intra-abdominal infection (IAI), and to determine whether delivery of tobramycin and vancomycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d148f8ba71f7c0989403ba50a78467ee
https://pubmed.ncbi.nlm.nih.gov/35636372
https://pubmed.ncbi.nlm.nih.gov/35636372
Autor:
Vajra S. Badha, Derek J. Overstreet, Brent Vernon, Daniel D. Gentry, W. Brian Saunders, Alex C. McLaren, John M. Heffernan, Rex C. Moore, Tim Feltis, Erin P. Childers, Tamas Nagy, Francis Calara, Michael B. Nguyen, Ryan Y. McLemore
Publikováno v:
J Biomed Mater Res B Appl Biomater
Surgical site infections (SSIs) are a persistent clinical challenge. Local antimicrobial delivery may reduce the risk of SSI by increasing drug concentrations and distribution in vulnerable surgical sites compared to what is achieved using systemic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfa413331c89e48c3e09001a48da6dc
https://europepmc.org/articles/PMC8608705/
https://europepmc.org/articles/PMC8608705/
Autor:
Antonia F. Chen, Alex C. McLaren
Publikováno v:
Journal of the American Academy of Orthopaedic Surgeons. 27:e721-e724
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172024edfeac68eb26627fb4eaeb2bf1
https://doi.org/10.5435/jaaos-d-18-00643
https://doi.org/10.5435/jaaos-d-18-00643
Autor:
John M. Heffernan, Rex C. Moore, Derek J. Overstreet, Alex C. McLaren, Vajra S. Badha, Brent Vernon, Erin P. Childers
Publikováno v:
Drug Deliv Transl Res
Local antimicrobial delivery is a promising strategy for improving treatment of deep surgical site infections (SSIs) by eradicating bacteria that remain in the wound or around its margins after surgical debridement. Eradication of biofilm bacteria ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19d6979f5db723c9e6ec342e6cd9ba4
https://doi.org/10.1007/s13346-019-00630-5
https://doi.org/10.1007/s13346-019-00630-5
Autor:
Scott R. Nodzo, Giovanni Riccio, Matthias D. Wimmer, John Stammers, Camelia E. Marculescu, Randi Silibovsky, K. Keely Boyle, Timothy L. Tan, Luca Cavagnaro, Feng-Chih Kuo, Parham Sendi, Harriet Hughes, Juan Pablo Horcajada, Alex C. McLaren
Publikováno v:
The Journal of Arthroplasty. 34:S225-S237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de10c27241a2316d875ac353b899cbad
https://doi.org/10.1016/j.arth.2018.09.074
https://doi.org/10.1016/j.arth.2018.09.074
Autor:
Peter K. Sculco, Timothy Wright, Michael-Alexander Malahias, Alexander Gu, Mathias Bostrom, Fares Haddad, Seth Jerabek, Michael Bolognesi, Thomas Fehring, Alejandro Gonzalez DellaValle, William Jiranek, William Walter, Wayne Paprosky, Donald Garbuz, Thomas Sculco, Matthew Abdel, Friedrich Boettner, Francesco Benazzo, Martin Buttaro, Daniel Choi, Charles Anderson Engh, Eduardo Garcia-Cimbrelo, Eduardo Garcia-Rey, Thorsten Gehrke, William L. Griffin, Erik Hansen, William J. Hozack, Stephen Jones, Gwo-Chin Lee, Joe Lipman, Andrew Manktelow, Alex C. McLaren, Rob Nelissen, Lawrence O’Hara, Carsten Perka, Scott Sporer
Publikováno v:
HSS Journal
Despite growing evidence supporting the evaluation, classification, and treatment of acetabular bone loss in revision hip replacement, advancements have not been systematically incorporated into a single document, and therefore, a comprehensive revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b874970d9d8a063913197eb47bab118
https://pubmed.ncbi.nlm.nih.gov/35082557
https://pubmed.ncbi.nlm.nih.gov/35082557