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of 14
pro vyhledávání: '"Alex C Stabell"'
Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir
Autor:
Alex C Stabell, Nicholas R Meyerson, Rebekah C Gullberg, Alison R Gilchrist, Kristofor J Webb, William M Old, Rushika Perera, Sara L Sawyer
Publikováno v:
eLife, Vol 7 (2018)
Human dengue viruses emerged from primate reservoirs, yet paradoxically dengue does not reach high titers in primate models. This presents a unique opportunity to examine the genetics of spillover versus reservoir hosts. The dengue virus 2 (DENV2) -
Externí odkaz:
https://doaj.org/article/43a1738476414835bfbd06fdae5b31d1
Autor:
Alex C Stabell, John Hawkins, Manqing Li, Xia Gao, Michael David, William H Press, Sara L Sawyer
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006066 (2016)
Schlafen11 (encoded by the SLFN11 gene) has been shown to inhibit the accumulation of HIV-1 proteins. We show that the SLFN11 gene is under positive selection in simian primates and is species-specific in its activity against HIV-1. The activity of h
Externí odkaz:
https://doaj.org/article/5134bafbcc32411fb24a0ec9ab17bb22
Autor:
Catherine M. Jankowski, Kristine M. Erlandson, Melissa P Wilson, Samantha MaWhinney, Alex C. Stabell
Publikováno v:
J Acquir Immune Defic Syndr
BACKGROUND People with HIV (PWH) may have lower daily activity levels compared with persons without HIV. We sought to determine the impact of initiating a supervised exercise program on the daily step count of sedentary PWH and uninfected controls. M
Autor:
Jacob T, Stanley, Alison R, Gilchrist, Alex C, Stabell, Mary A, Allen, Sara L, Sawyer, Robin D, Dowell
Publikováno v:
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 25
Flaviviruses such as dengue encode a protease that is essential for viral replication. The protease functions by cleaving well-conserved positions in the viral polyprotein. In addition to the viral polyprotein, the dengue protease cleaves at least on
Autor:
Robin D. Dowell, Sara L. Sawyer, Alex C. Stabell, Jacob T. Stanley, Mary A. Allen, Alison R. Gilchrist
Publikováno v:
PSB
Flaviviruses such as dengue encode a protease that is essential for viral replication. The protease functions by cleaving well-conserved positions in the viral polyprotein. In addition to the viral polyprotein, the dengue protease cleaves at least on
Autor:
Sara L. Sawyer, Carolyn J. Decker, Kelsey C. Haist, Halley R. Steiner, Mark D. Stenglein, Roy Parker, Eric M. Poeschla, James H. Morrison, Laura L. Hoon-Hanks, Thomas E. Morrison, Alex C. Stabell
Publikováno v:
Viruses, Vol 11, Iss 10, p 943 (2019)
Viruses
Volume 11
Issue 10
Viruses
Volume 11
Issue 10
RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that RNA viruses produce double-stranded RNA (dsRNA) while replicating. Purifying
Autor:
Cody J. Warren, Will T. Fattor, Alex C. Stabell, Sara L. Sawyer, Nicholas R. Meyerson, Gregory K. Wilkerson
Publikováno v:
Proceedings of the National Academy of Sciences
Pandemic HIV-1 (group M) emerged following the cross-species transmission of a simian immunodeficiency virus from chimpanzees (SIVcpz) to humans. Primate lentiviruses (HIV/SIV) require the T cell receptor CD4 to enter into target cells. By surveying
Autor:
Katie Lee, Yi Zeng, Sara L. Sawyer, Jae U. Jung, Zanxian Xia, Junjie Zhang, Ting Liu, Canhua Huang, Linshen Xie, Alex C. Stabell, Simin Xu, Pinghui Feng, Gil Ju Seo, Shanping He, Junhua Li, Lin Chen, Na Xie, Jun Zhao
Summary Herpes simplex virus 1 (HSV-1) establishes infections in humans and mice, but some non-human primates exhibit resistance via unknown mechanisms. Innate immune recognition pathways are highly conserved but are pivotal in determining susceptibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211ffe4a76014228733cd03bb441965d
https://europepmc.org/articles/PMC6094942/
https://europepmc.org/articles/PMC6094942/
Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir
Autor:
Sara L. Sawyer, Kristofor J. Webb, Nicholas R. Meyerson, Rushika Perera, William M. Old, Rebekah C. Gullberg, Alison R. Gilchrist, Alex C. Stabell
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Human dengue viruses emerged from primate reservoirs, yet paradoxically dengue does not reach high titers in primate models. This presents a unique opportunity to examine the genetics of spillover versus reservoir hosts. The dengue virus 2 (DENV2) -
Autor:
Rebekah C. Gullberg, Alison R. Gilchrist, Sara L. Sawyer, William M. Old, Alex C. Stabell, Rushika Perera, Kristofor J. Webb, Nicholas R. Meyerson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f80c91f3d562af4cd0d61feb6e3ca93
https://doi.org/10.7554/elife.31919.022
https://doi.org/10.7554/elife.31919.022