Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alex Brinker"'
MAK122: A Novel Drug Utilizing Innovative Fracture Site Targeting Technology to Improve Bone Healing
Autor:
Nicholas Hux, Jeffery Nielson, Caio De Andrade Staut, Vincent Alentado, Abduallah Elsayed, Christopher Dalloul, Samuel Zike, Nikhil Tewari, Murad Nazzal, Hanisha Battina, Alex Brinker, Mustafah Shaikh, Sarah Myers, Rachel Blosser, Ushashi Dadwal, Jiliang Li, Stewart Low, Philip Low, Melissa Kacena
Publikováno v:
Proceedings of IMPRS. 4
Megakaryocytes play a pivotal role in the bone fracture healing process through enhancing osteoblast proliferation, osteoclastogenesis, and angiogenesis. Current fracture repair therapies require direct implantation during surgery (BMP-2, grafts etc.
Autor:
Abduallah Elsayed, Jeffery Nielsen, Natalie Taylor, Mohammed Juboori, Caio de Andrade Staut, Vincent Alentado, Nicholas Hux, Christopher Dalloul, Samuel Zike, Nikhil Tewari, Murad Nazzal, Hanisha Battina, Alex Brinker, Mustafah Shaikh, Sarah Myers, Rachel Blosser, Ushashi Dadwal, Mary Niedrauer, Stewart Low, Philip Low, Jiliang Li, Fletcher A. White, Melissa A. Kacena
Publikováno v:
Proceedings of IMPRS. 4
Non-union bone fracture occurs in 5-10% of fracture injuries. Interventions include surgery with local implantation of autograft, allograft, demineralized bone matrix, and/or bone morphogenetic proteins. These types of fracture injuries are also acco
Autor:
Michael Savaglio, Roman M. Natoli, Todd O. McKinley, Nicklaus H. Diggins, Zachary J. Gunderson, Melissa A. Kacena, Gremah Adam, Seungyup Sun, Aamir Tucker, Alex Brinker, Benjamin T. Corona
Publikováno v:
Proceedings of IMPRS. 2
Background and Hypothesis: Injury to soft tissue with volumetric muscle loss (VML) concomitant to segmental bone defects (SBDs) can be difficult to treat. One potential option is skeletal muscle autograft (SMA). We hypothesize the maximal torque meas
Autor:
Anthony J. Milto, Roman M. Natoli, Todd O. McKinley, Paul Childress, Gremah Adam, Melissa A. Kacena, Michael Savaglio, Alex Brinker, Venkateswaran Ganesh, Aamir Tucker, Zachary J. Gunderson, Alexander W. Peters
Publikováno v:
Proceedings of IMPRS. 1
Background/Hypothesis: Few large animal bone injury models exist. We present a porcine tibial model of metacritical and critical sized bone defects for the simulation of traumatic bone injuries. Project Methods: 16 pigs were used in this study. The p
Autor:
Roman M. Natoli, Benjamin T. Corona, Alexander W. Peters, Gremah Adam, Anthony J. Milto, Zachary J. Gunderson, Paul Childress, Venkateswaran Ganesh, Michael Savaglio, Aamir Tucker, Alex Brinker, Todd O. McKinley, Melissa A. Kacena
Publikováno v:
Proceedings of IMPRS. 1
Background and Hypothesis: Soft tissue injury surrounding tibia fractures is a key determinant of surgical care decisions and healing outcomes. We have established a porcine tibia fracture model with a corresponding volumetric muscle loss (VML) injur