Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Alex Bokov"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 48-48 (2021)
ABSTRACT IMPACT: Laying the groundwork for better predictive algorithms to inform clinical decisions and planning. OBJECTIVES/GOALS: Frailty scores predict poor patient outcomes. Validated against highly relevant outcomes, such scores can be used to
Externí odkaz:
https://doaj.org/article/ff00e0abd06344518f0e6dbca4429582
Autor:
Haihui Pan, Kunhua Qin, Zhanyong Guo, Yonggang Ma, Craig April, Xiaoli Gao, Thomas G. Andrews, Alex Bokov, Jianhua Zhang, Yidong Chen, Susan T. Weintraub, Jian-Bing Fan, Degeng Wang, Yanfen Hu, Gregory J. Aune, Merry L. Lindsey, Rong Li
Publikováno v:
Cell Reports, Vol 7, Iss 1, Pp 79-85 (2014)
Negative elongation factor (NELF) is known to enforce promoter-proximal pausing of RNA polymerase II (Pol II), a pervasive phenomenon observed across multicellular genomes. However, the physiological impact of NELF on tissue homeostasis remains uncle
Externí odkaz:
https://doaj.org/article/68c97ea5df3a40368658fb58edf0679e
Autor:
Wilson C Fok, Yidong Chen, Alex Bokov, Yiqiang Zhang, Adam B Salmon, Vivian Diaz, Martin Javors, William H Wood, Yongqing Zhang, Kevin G Becker, Viviana I Pérez, Arlan Richardson
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83988 (2014)
Rapamycin was found to increase (11% to 16%) the lifespan of male and female C57BL/6J mice most likely by reducing the increase in the hazard for mortality (i.e., the rate of aging) term in the Gompertz mortality analysis. To identify the pathways th
Externí odkaz:
https://doaj.org/article/b87bcfcb78e646c3b77649ae5180f55d
Autor:
Suresh K. Bhavnani, Weibin Zhang, Daniel Bao, Mukaila Raji, Veronica Ajewole, Rodney Hunter, Yong-Fang Kuo, Susanne Schmidt, Monique R. Pappadis, Alex Bokov, Timothy Reistetter, Shyam Visweswaran, Brian Downer
A.ABSTRACTProject BackgroundSocial determinants of health (SDoH), such as financial resource strain and housing instability, account for between 30-55% of people’s health outcomes. While many studies have identified strong associations among specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5a47bba3922e2d89786c923223c350
https://doi.org/10.1101/2023.01.27.23285125
https://doi.org/10.1101/2023.01.27.23285125
Autor:
Timothy Reistetter, Alex Bokov, Susanne Schmidt, John Prochaska, Allen Haas, Mei-Ling Lin, Julianna Dean, Yong-Fang Kuo, Karl Eschbach
Publikováno v:
Archives of Physical Medicine and Rehabilitation. 103:e186-e187
Publikováno v:
Health Serv Res
RESEARCH OBJECTIVE: To predict occurrence of preventable patient safety events using only data elements that are almost universally supported in EHR systems. STUDY DESIGN: We drew a random sample was drawn from the EHR records of adult patients not r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02547efc0afbce0e817ea7c0b7e6bb1d
https://europepmc.org/articles/PMC8441366/
https://europepmc.org/articles/PMC8441366/
Autor:
Ann M. Davis, Lemuel R. Waitman, Helena H. Laroche, Lawrence P. Hanrahan, Alex Bokov, Sarah Schlachter
Publikováno v:
JMIR Research Protocols
Background: Electronic health records (EHRs) are ubiquitous. Yet little is known about the use of EHRs for prospective research purposes, and even less is known about patient perspectives regarding the use of their EHR for research. Objective: This p
Autor:
Yuji Ikeno, Michael E. Walsh, Alex Bokov, Holly Van Remmen, Yuhong Liu, Arlan Richardson, Yiqiang Zhang, Young C. Jang, Viviana I. Pérez
Publikováno v:
Mechanisms of Ageing and Development. 154:1-8
Genetic ablation of CuZn-superoxide dismutase (Sod1) in mice (Sod1(-/-) mice) leads to shortened lifespan with a dramatic increase in hepatocellular carcinoma and accelerated aging phenotypes, including early onset sarcopenia. To study the tissue spe
Publikováno v:
ICCS
Procedia Computer Science
Procedia Computer Science
There are many legitimate reasons why standards for formatting of biomedical research data are lengthy and complex (Souza, Kush, & Evans, 2007). However, the common scenario of a biostatistician simply needing to import a given dataset into their sta
Autor:
Megan B. Borror, Erin Munkácsy, Shane L. Rea, Oxana Radetskaya, Alex Bokov, Robert J. Mishur, Rebecca Lane, Haley Beam, Lokendra Kumar Sharma, Maruf Khan, Yidong Bai
Publikováno v:
Aging Cell
Summary Disruption of mitochondrial respiration in the nematode Caenorhabditis elegans can extend lifespan. We previously showed that long‐lived respiratory mutants generate elevated amounts of α‐ketoacids. These compounds are structurally relat