Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Alex B Blair"'
Autor:
Kenji Fujiwara, Hao Jing, Brian Herbst, MacKenzie Zarecki, Annie Wu, Elaine Bigelow, Keyu Li, Neolle Jurcak, Alex B Blair, Michael Wichroski, Jordan Blum, Nathan Cheadle, Jennifer Koenitzer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/1b5b58fe2f39457890d602f409337ca9
Autor:
Kenji Fujiwara, Hao Jing, Brian Herbst, MacKenzie Zarecki, Annie Wu, Elaine Bigelow, Keyu Li, Neolle Jurcak, Alex B Blair, Michael Wichroski, Jordan Blum, Nathan Cheadle, Jennifer Koenitzer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/ad7572f4311c4f74a5317aac743bdf3d
Autor:
Kenji Fujiwara, Hao Jing, Brian Herbst, MacKenzie Zarecki, Annie Wu, Elaine Bigelow, Keyu Li, Neolle Jurcak, Alex B Blair, Michael Wichroski, Jordan Blum, Nathan Cheadle, Jennifer Koenitzer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Radiation therapy (RT) has the potential to enhance the efficacy of immunotherapy, such as checkpoint inhibitors, which has dramatically altered the landscape of treatments for many cancers, but not yet for pancreatic ductal adenocarcinoma
Externí odkaz:
https://doaj.org/article/468e45316311472f8fc837a650b30475
Autor:
Keyu Li, Junke Wang, Rui Zhang, Jiawei Zhou, Birginia Espinoza, Nan Niu, Jianxin Wang, Noelle Jurcak, Noah Rozich, Arsen Osipov, MacKenzie Henderson, Vanessa Funes, Melissa Lyman, Alex B. Blair, Brian Herbst, Mengni He, Jialong Yuan, Diego Trafton, Chunhui Yuan, Michael Wichroski, Xubao Liu, Juan Fu, Lei Zheng
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract Due to the challenge for intratumoral administration, innate agonists have not made it beyond preclinical studies for efficacy testing in most tumor types. Pancreatic ductal adenocarcinoma (PDAC) has a hostile tumor microenvironment that ren
Externí odkaz:
https://doaj.org/article/bfd08d1266be4922922c25e98fb0b353
Autor:
Logan R. McNeil, BA, Alex B. Blair, MD, Robert W. Krell, MD, Chunmeng Zhang, MD, Aslam Ejaz, MD, MPH, Vincent P. Groot, MD, PhD, Georgios Gemenetzis, MD, James C. Padussis, MD, Massimo Falconi, MD, Christopher L. Wolfgang, MD, PhD, Matthew J. Weiss, MD, Chandrakanth Are, MD, MBA, Jin He, MD, PhD, Bradley N. Reames, MD, MS
Publikováno v:
Surgery Open Science, Vol 10, Iss , Pp 97-105 (2022)
Background: Recent literature suggests wide variations exist in the international management of locally advanced pancreatic cancer. This study sought to evaluate how geography contributes to variations in management of locally advanced pancreatic can
Externí odkaz:
https://doaj.org/article/411b220dbef84f7aaf33c5c02f42df44
Autor:
Victoria M. Kim, Alex B. Blair, Peter Lauer, Kelly Foley, Xu Che, Kevin Soares, Tao Xia, Stephen T. Muth, Jennifer Kleponis, Todd D. Armstrong, Christopher L. Wolfgang, Elizabeth M. Jaffee, Dirk Brockstedt, Lei Zheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Immune checkpoint inhibitors are not effective for pancreatic ductal adenocarcinoma (PDAC) as single agents. Vaccine therapy may sensitize PDACs to checkpoint inhibitor treatments. Annexin A2 (ANXA2) is a pro-metastasis protein, p
Externí odkaz:
https://doaj.org/article/54280b372b12429ab75fc9c756155e36
Autor:
May Tun Saung, Stephen Muth, Ding Ding, Dwayne L. Thomas, Alex B. Blair, Takahiro Tsujikawa, Lisa Coussens, Elizabeth M. Jaffee, Lei Zheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background The pancreatic cancer vaccine, GVAX, induces novel lymphoid aggregates in the otherwise immune quiescent pancreatic ductal adenocarcinoma (PDAC). GVAX also upregulates the PD-1/PD-L1 pathway, and a pre-clinical model demonstrated
Externí odkaz:
https://doaj.org/article/67cbbd738fa74cc7b79e195ba66bac18
Autor:
Lei Zheng, Christopher L. Wolfgang, Richard A. Burkhart, Jin He, Lisa M. Coussens, Takahiro Tsujikawa, Elizabeth M. Jaffee, Todd D. Armstrong, Barbara Blouw, Nathalie Lokker, May Tun Saung, Stephen T. Muth, Victoria M. Kim, Alex B. Blair
Supplemental Data: Figure S1: Pathologic representation of hemispleen liver metastases; Figure S2: Treatment schema; Figure S3: Supplemental survival; Figure S4: FACS PD1/PDL1 expression; Figure S5: Myeloid cell FACS; Figure S6: Multiplex IHC of myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173c935d5d37b4ac9a455780845662b5
https://doi.org/10.1158/1078-0432.22471740
https://doi.org/10.1158/1078-0432.22471740
Autor:
Lei Zheng, Christopher L. Wolfgang, Richard A. Burkhart, Jin He, Lisa M. Coussens, Takahiro Tsujikawa, Elizabeth M. Jaffee, Todd D. Armstrong, Barbara Blouw, Nathalie Lokker, May Tun Saung, Stephen T. Muth, Victoria M. Kim, Alex B. Blair
Purpose:Myeloid cells are a prominent immunosuppressive component within the stroma of pancreatic ductal adenocarcinoma (PDAC). Previously, targeting myeloid cells has had limited success. Here, we sought to target the myeloid cells through modifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696664909a2932d434533b1e4556b1e1
https://doi.org/10.1158/1078-0432.c.6527988.v1
https://doi.org/10.1158/1078-0432.c.6527988.v1
Autor:
William H. Burns, Kelly J. Lafaro, Jin He, Richard A. Burkhart, Matthew J. Weiss, John L. Cameron, Christopher L. Wolfgang, James F. Griffin, Joseph R. Habib, Ross M. Beckman, Alex B. Blair
Publikováno v:
HPB (Oxford)
BACKGROUND: Main-duct (MD) intraductal papillary mucinous neoplasm (IPMN) is associated with malignancy risk. There is a lack of consensus on treatment (partial or total pancreatectomy) when the MD is diffusely involved. We sought to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda0ab3f3a2d7cb2973ca6795c7f8369
https://doi.org/10.1016/j.hpb.2021.09.013
https://doi.org/10.1016/j.hpb.2021.09.013