Interactions between Candida albicans and Enterococcus faecalis in an Organotypic Oral Epithelial Model

Autor: Akshaya Lakshmi Krishnamoorthy, Alex A. Lemus, Adline Princy Solomon, Alex M. Valm, Prasanna Neelakantan

Publikováno v: Microorganisms, Vol 8, Iss 11, p 1771 (2020)

Candida albicans as an opportunistic pathogen exploits the host immune system and causes a variety of life-threatening infections. The polymorphic nature of this fungus gives it tremendous advantage to breach mucosal barriers and cause oral and disse

Externí odkaz: https://doaj.org/article/e11695274217490e852cb1d2de4a37b9

Unmixing Biological Fluorescence Image Data with Sparse and Low-Rank Poisson Regression

Autor: Ruogu Wang, Alex A Lemus, Colin M Henneberry, Yiming Ying, Yunlong Feng, Alex M Valm

Motivation Multispectral biological fluorescence microscopy has enabled the identification of multiple targets in complex samples. The accuracy in the unmixing result degrades (i) as the number of fluorophores used in any experiment increases and (ii

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5a1488a97519dbff65b4f1f4770f37
https://doi.org/10.1101/2023.01.06.523044

Estimating the glutamate transporter surface density in distinct sub-cellular compartments of mouse hippocampal astrocytes

Autor: Anca Radulescu, Annalisa Scimemi, Alex A. Lemus, Damian G. Zuloaga, Cassandra Williams, Gabrielle C. Todd, Ashley M. Kopec, Haley E. Chesbro, Benjamin Bennink, Justin R. Bourgeois

Publikováno v: PLoS Computational Biology, Vol 18, Iss 2, p e1009845 (2022)

Glutamate transporters preserve the spatial specificity of synaptic transmission by limiting glutamate diffusion away from the synaptic cleft, and prevent excitotoxicity by keeping the extracellular concentration of glutamate at low nanomolar levels.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ab4cd8dcb827d782e412650470aa28
https://doi.org/10.1101/2021.05.08.443234

Enterococcus faecalis Enhances Candida albicans Mediated Tissue Destruction in a Strain-Dependent Manner

Autor: Alex A Lemus, Adline Princy Solomon, Alex M. Valm, Prasanna Neelakantan, Akshaya Lakshmi Krishnamoorthy

Candida albicans as an opportunistic pathogen exploits the host immune system and causes a variety of life-threatening infections. The polymorphic nature of this fungus gives it tremendous advantage to breach mucosal barriers and cause a variety of o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185d043f069be207467be9256124089a
https://doi.org/10.20944/preprints202010.0162.v1

A feedback loop between heterochromatin and the nucleopore complex controls germ-cell-to-oocyte transition during Drosophila oogenesis.

Autor: Sarkar K; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Kotb NM; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA; Department of Biomedical Sciences, School of Public Health, University at Albany SUNY, Albany, NY 12222, USA., Lemus A; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Martin ET; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., McCarthy A; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Camacho J; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Iqbal A; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Valm AM; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Sammons MA; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA., Rangan P; Department of Biological Sciences and RNA Institute, University at Albany SUNY, Albany, NY 12222, USA. Electronic address: prashanth.rangan@mssm.edu.

Publikováno v: Developmental cell [Dev Cell] 2023 Nov 20; Vol. 58 (22), pp. 2580-2596.e6. Date of Electronic Publication: 2023 Sep 05.