Zobrazeno 1 - 10 of 840 pro vyhledávání: '"Alex A Adjei"'
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Akademický článek
A phase 2 and pharmacological study of sapanisertib in patients with relapsed and/or refractory acute lymphoblastic leukemia
Autor: Aref Al‐Kali, Ibrahim Aldoss, Pamela J. Atherton, Carrie A. Strand, Bijal Shah, Jonathan Webster, Bhavana Bhatnagar, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Sarah A. Buhrow, Jianping Kong, Joel M. Reid, Alex A. Adjei, Scott H. Kaufmann
Publikováno v: Cancer Medicine, Vol 12, Iss 23, Pp 21229-21239 (2023)
Abstract Background Despite recent approval of several new agents, relapsed acute lymphoblastic leukemia (ALL) remains challenging to treat. Sapanisertib (MLN0128/TAK‐228) is an oral TORC1/2 inhibitor that exhibited preclinical activity against ALL
Externí odkaz: https://doaj.org/article/55ca42b54be149f0b8acb389ece68dc9
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4
Akademický článek
A challenging case of stage IV EGFR-mutant lung cancer with histologic transformation and multiple resistance mechanisms
Autor: Joel Rivera-Concepcion, Ying-Chun Lo, Dipesh Uprety, Alex A. Adjei, Vinicius Ernani, Konstantinos Leventakos
Publikováno v: Current Problems in Cancer: Case Reports, Vol 13, Iss , Pp 100284- (2024)
This clinical case presents a patient with NSCLC who experienced on-target resistant mutations and tumor cell transformation from adenocarcinoma to large cell neuroendocrine and small cell carcinoma. Our patient was successfully treated with a combin
Externí odkaz: https://doaj.org/article/89b01e3fc5fe4031b3866f1dd44b3b45
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5
Akademický článek
Service quality affecting student satisfaction in higher education institutions in Ghana
Autor: George Kofi Amoako, George Oppong Ampong, Antoinette Yaa Benewaa Gabrah, Felicia de Heer, Alex Antwi-Adjei
Publikováno v: Cogent Education, Vol 10, Iss 2 (2023)
AbstractHigher education stakeholders have re-strategized to identify the unique competitive causes of comfortability among students’ satisfaction. Student satisfaction has been largely observed in the literature as a significant strategy and compe
Externí odkaz: https://doaj.org/article/34a7c3df8a6346edb8577ce968468bf9
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7
Akademický článek
Our Work Is Done, and You Are in Good Hands
Autor: Alex A. Adjei, MD, PhD
Publikováno v: JTO Clinical and Research Reports, Vol 4, Iss 1, Pp 100447- (2023)
Externí odkaz: https://doaj.org/article/8ae9217b682e499d9b4f68ab8639051f
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9
Akademický článek
Efficacy of immune checkpoint inhibitors in non-small cell lung cancer: A systematic review and meta-analysis
Autor: Fang Yang, Yucai Wang, Lin Tang, Aaron Scott Mansfield, Alex A. Adjei, Konstantinos Leventakos, Narjust Duma, Jia Wei, Lifeng Wang, Baorui Liu, Julian R. Molina
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
BackgroundImmune checkpoint inhibitors (ICIs) have demonstrated remarkable efficacy in non-small cell lung cancer (NSCLC). However, only a minority of NSCLC patients benefit from ICIs, and whether the magnitude of benefit is specific factor-dependent
Externí odkaz: https://doaj.org/article/c8ad526a23f0433695f64c792fc2a9e0
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10
Akademický článek
Inflation of tumor mutation burden by tumor-only sequencing in under-represented groups
Autor: Yan W. Asmann, Kaushal Parikh, P. Leif Bergsagel, Haidong Dong, Alex A. Adjei, Mitesh J. Borad, Aaron S. Mansfield
Publikováno v: npj Precision Oncology, Vol 5, Iss 1, Pp 1-4 (2021)
Abstract With the recent FDA approval of tumor mutational burden-high (TMB-H) status as a biomarker for treatment with a PD-1 inhibitor regardless of tumor type, accurate assessment of patient-specific TMB is more critical now more than ever. Using p
Externí odkaz: https://doaj.org/article/953d0fc861874af3a5542c24c24ac1b0
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