Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Alex A, Meier"'
Autor:
Alex A. Meier, Hee-Jung Moon, Ronald Toth, Ewa Folta-Stogniew, Krzysztof Kuczera, C. Russell Middaugh, Minae Mure
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1846 (2021)
Lysyl oxidase-like 2 (LOXL2) has emerged as a promising therapeutic target against metastatic/invasive tumors and organ and tissue fibrosis. LOXL2 catalyzes the oxidative deamination of lysine and hydroxylysine residues in extracellular matrix (ECM)
Externí odkaz:
https://doaj.org/article/8ff12db5c7694f44b9580dd423ef49a8
Autor:
Alex A. Meier, Hee-Jung Moon, Sinan Sabuncu, Priya Singh, Trey A. Ronnebaum, Siyu Ou, Justin T. Douglas, Timothy A. Jackson, Pierre Moënne-Loccoz, Minae Mure
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13966
Lysyl oxidase-2 (LOXL2) is a Cu2+ and lysine tyrosylquinone (LTQ)-dependent amine oxidase that catalyzes the oxidative deamination of peptidyl lysine and hydroxylysine residues to promote crosslinking of extracellular matrix proteins. LTQ is post-tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d3cd2e33f1af9a48237bff998eb5d5
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13385
Lysyl oxidase–like 2 (LOXL2) has been recognized as an attractive drug target for anti–fibrotic and anti–tumor therapies. However, the structure–based drug design of LOXL2 has been very challenging due to the lack of structural information of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df6df249a122afeafb557aeab802300
Autor:
Wade C. Henke, Yun Peng, Alex A. Meier, Etsuko Fujita, David C. Grills, Dmitry E. Polyansky, James D. Blakemore
Protonation reactions involving organometallic complexes are ubiquitous in redox chemistry and often result in the generation of reactive metal hydrides. However, some organometallic species supported by η 5 -pentamethylcyclopentadienyl (Cp*) ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9039a54ca4e93ae8b068cf20c1135d0f
https://doi.org/10.26434/chemrxiv-2022-c1cxb
https://doi.org/10.26434/chemrxiv-2022-c1cxb
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 5879
Lysyl oxidase-like 2 (LOXL2) catalyzes the oxidative deamination of peptidyl lysines and hydroxylysines to promote extracellular matrix remodeling. Aberrant activity of LOXL2 has been associated with organ fibrosis and tumor metastasis. The lysine ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cf44998b2da74ad66572be75fdc7a5
https://pubmed.ncbi.nlm.nih.gov/35682561
https://pubmed.ncbi.nlm.nih.gov/35682561
Autor:
Alex von Meier, Gijs-Jan van Blokland
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59799df3128765fb062ff14a1cce9348
https://doi.org/10.4271/931279
https://doi.org/10.4271/931279
Autor:
Meier, Alex A.1 (AUTHOR), Moon, Hee-Jung1 (AUTHOR), Sabuncu, Sinan2 (AUTHOR), Singh, Priya1 (AUTHOR), Ronnebaum, Trey A.1 (AUTHOR), Ou, Siyu1 (AUTHOR), Douglas, Justin T.1 (AUTHOR), Jackson, Timothy A.1 (AUTHOR), Moënne-Loccoz, Pierre2 (AUTHOR), Mure, Minae1 (AUTHOR) mmure@ku.edu
Publikováno v:
International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 22, p13966. 17p.
Autor:
Meier, Alex A.1 (AUTHOR), Kuczera, Krzysztof1,2 (AUTHOR) kkuczera@ku.edu, Mure, Minae1 (AUTHOR) kkuczera@ku.edu
Publikováno v:
International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 21, p13385. 19p.
Autor:
Meier, Alex A.1 (AUTHOR), Go, Eden P.1 (AUTHOR), Moon, Hee-Jung1 (AUTHOR), Desaire, Heather1 (AUTHOR) aameier@ku.edu, Mure, Minae1 (AUTHOR) hdesaire@ku.edu
Publikováno v:
International Journal of Molecular Sciences. Jun2022, Vol. 23 Issue 11, p5879-5879. 17p.
Autor:
Henke, Wade C., Yun Peng, Meier, Alex A., Etsuko Fujita, Grills, David C., Polyansky, Dmitry E., Blakemore, James D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/23/2023, Vol. 120 Issue 21, p1-9, 74p