Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Alex Sevanian"'
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 1, Pp 115-122 (2005)
Electronegative low density lipoprotein (LDL−) formation that structurally resembles LDL− isolated from plasma was evaluated after LDL treatment with snake venom phospholipase A2 (PLA2). PLA2 treatment of LDL increased its electrophoretic mobilit
Externí odkaz:
https://doaj.org/article/379201de77ee44d4867ae78585b878a0
Autor:
John M. Hayden, Libuse Brachova, Karen Higgins, Lewis Obermiller, Alex Sevanian, Srikrishna Khandrika, Peter D. Reaven
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 1, Pp 26-35 (2002)
Oxidized LDL (OxLDL) is composed of many potentially proatherogenic molecules, including oxysterols. Of the oxysterols, 7-ketocholesterol (7-KC) is found in relatively large abundance in OxLDL, as well as in atherosclerotic plaque and foam cells in v
Externí odkaz:
https://doaj.org/article/5b4741c2cddf4a9f8be40086864adebd
Autor:
Lijiang Shen, Alex Sevanian
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 5, Pp 813-823 (2001)
Oxidized LDL (oxLDL) produced a rapid depletion of intracellular glutathione (GSH) followed by an adaptive increase in J774 A.1 macrophages. OxLDL also induced a transient increase in the levels of γ-glutamylcysteine synthetase heavy subunit (γ-GCS
Externí odkaz:
https://doaj.org/article/9e2c134e9f6e4123a75f90762bee67c0
Autor:
Mohamad Navab, Susan Y. Hama, G.M. Anantharamaiah, Kholood Hassan, Greg P. Hough, Andrew D. Watson, Srinivasa T. Reddy, Alex Sevanian, Gregg C. Fonarow, Alan M. Fogelman
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 9, Pp 1495-1508 (2000)
Treatment of human artery wall cells with apolipoprotein A-I (apoA-I), but not apoA-II, with an apoA-I peptide mimetic, or with high density lipoprotein (HDL), or paraoxonase, rendered the cells unable to oxidize low density lipoprotein (LDL). Human
Externí odkaz:
https://doaj.org/article/c1eb1df09a4a46d7966ebf33712330a1
Autor:
Alex Sevanian
Publikováno v:
Cellular Antioxidant Defense Mechanisms ISBN: 9780429289309
Cellular Antioxidant Defense Mechanisms
Cellular Antioxidant Defense Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51fbad04d4a148eb4310c8ddd1bb56fa
https://doi.org/10.1201/9780429289309-4
https://doi.org/10.1201/9780429289309-4
Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells
Autor:
Tzung K. Hsiai, Mahsa Rouhanizadeh, Srinivasa T. Reddy, Lucas DeMaio, Alex Sevanian, Juliana Hwang
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H674-H683
Oxidized l-α-1-palmitoyl-2-arachidonoyl- sn-glycero-3-phosphorylcholine (OxPAPC), a component of minimally modified LDL, induces production of proinflammatory cytokines and development of atherosclerotic lesions. We tested the hypothesis that OxPAPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48fdcd28dea26b297b919a90ed9164a
https://doi.org/10.1152/ajpheart.00554.2005
https://doi.org/10.1152/ajpheart.00554.2005
Autor:
Elaine Apolinário, Dulcinéia Saes Parra Abdalla, Joelma Maria Araujo de Oliveira, Alex Sevanian, Nágila Raquel Teixeira Damasceno, I. Fernandes
Publikováno v:
Clinical Biochemistry. 39:28-38
To produce a monoclonal antibody (MAb) against electronegative LDL (LDL-) for detecting this modified lipoprotein in blood plasma and tissues.LDL- was isolated from human blood plasma and used as an antigen for immunization of Balb/c mice. Lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42c39fe4e8dd82a51cff0e5e2672a2d
https://doi.org/10.1016/j.clinbiochem.2005.09.014
https://doi.org/10.1016/j.clinbiochem.2005.09.014
Autor:
Juliana Hwang, Bernard Lassègue, Tzung K. Hsiai, Alex Sevanian, Laura Marcu, Roza E. Clempus, Mahsa Rouhanizadeh
Publikováno v:
Free Radical Biology and Medicine. 39:1512-1522
Modified low-density lipoprotein (LDL) induces reactive oxygen species (ROS) production by vascular cells. It is unknown if specific oxidized components in these LDL particles such as oxidized-1-palmitoyl-2-arachidonoyl- sn -glycero-3-phosphorylcholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4c4f9d68db423ccf58667edea09af
https://doi.org/10.1016/j.freeradbiomed.2005.07.013
https://doi.org/10.1016/j.freeradbiomed.2005.07.013
Autor:
H. Hampl, Ingrid Wiswedel, Werner Siems, Wolfgang Augustin, S Quast, Daniela Peter, Alex Sevanian, Francesco Carluccio, Tilman Grune
Publikováno v:
Kidney and Blood Pressure Research. 28:302-306
Background/Aims: Oxidative stress occurs in chronic renal failure patients undergoing hemodialysis (HD). The objective of our study was to measure oxidation products of cholesterols, so-called oxysterols, in the serum of HD patients in comparison to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958764fc880613c95b5a647fdff836e7
https://doi.org/10.1159/000091133
https://doi.org/10.1159/000091133
Autor:
Dulcinéia Saes Parra Abdalla, André Arpad Faludi, Marcelo Chiara Bertolami, Edimar Cristiano Pereira, Alex Sevanian
Publikováno v:
Free Radical Biology and Medicine. 37:1440-1448
Among the pleiotropic effects of statins, their antioxidant action may be involved in their protective effects. Thus, we investigated the antioxidant effect of simvastatin, associated or not with alpha-tocopherol, on levels of electronegative low-den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1955b4c2e0cff001c7c26c8b5139bff3
https://doi.org/10.1016/j.freeradbiomed.2004.07.019
https://doi.org/10.1016/j.freeradbiomed.2004.07.019