Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alex, de Marco"'
Autor:
Charles Bayly-Jones, Christopher J. Lupton, Claudia Fritz, Hariprasad Venugopal, Daniel Ramsbeck, Michael Wermann, Christian Jäger, Alex de Marco, Stephan Schilling, Dagmar Schlenzig, James C. Whisstock
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Meprin α is a proteolytic regulator of the extracellular matrix that forms enormous oligomeric filaments of unknown purpose. Here, the authors determine by cryo-EM the structural basis of the meprin supercoiled filament and further characterise a sm
Externí odkaz:
https://doaj.org/article/38630ad799064ddaba5722e41c9934b6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The analysis of spermatozoa morphology is fundamental to understand male fertility and the etiology of infertility. Traditionally scanning electron microscopy (SEM) has been used to define surface topology. Recently, however, it has become a critical
Externí odkaz:
https://doaj.org/article/fcdfac02e9054f9f9e7fda6b918769ad
Publikováno v:
APL Photonics, Vol 5, Iss 10, Pp 106110-106110-7 (2020)
We report on the experimental demonstration of refractive micro-optical elements with arbitrary exponential surface profiles. Refractive optical elements such as lenses and axicons have parabolic (power-exponent of two) or conical (power-exponent of
Externí odkaz:
https://doaj.org/article/c32b0d4e2424467f9cba5d73a5c0c481
Publikováno v:
eLife, Vol 9 (2020)
Human Cytomegalovirus (HCMV) infects over half the world's population, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals. To expand the molecular knowledge governing virion maturation, we analy
Externí odkaz:
https://doaj.org/article/a071ccccecbd48ac9eef34aa58b408e5
Autor:
Johnson Mak, Alex de Marco
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Cryo-electron microscopy has undergone a revolution in recent years and it has contributed significantly to a number of different areas in biological research. In this manuscript, we will describe some of the recent advancements in cryo-elec
Externí odkaz:
https://doaj.org/article/834e9a969ffd4f928fa2f5c0fada456e
Autor:
Shuo Zhang, Gediminas Gervinskas, Shi Qiu, Hari Venugopal, Ross K. W. Marceau, Alex de Marco, Jian Li, Jing Fu
Publikováno v:
Nano Letters. 22:6501-6508
New high-resolution imaging methods for biological samples such as atom probe tomography (APT), facilitated by the invention of laser-pulsed atom probes and cryo-transfer procedures, have recently emerged. However, ensuring the vitreous state of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7abb7c42f95ec4e1306e8adaf862f0
https://doi.org/10.1021/acs.nanolett.2c01495
https://doi.org/10.1021/acs.nanolett.2c01495
Autor:
Sergey Gorelick, Genevieve Buckley, Gediminas Gervinskas, Travis K Johnson, Ava Handley, Monica Pia Caggiano, James C Whisstock, Roger Pocock, Alex de Marco
Publikováno v:
eLife, Vol 8 (2019)
Cryo-electron tomography (cryo-ET) is emerging as a revolutionary method for resolving the structure of macromolecular complexes in situ. However, sample preparation for in situ Cryo-ET is labour-intensive and can require both cryo-lamella preparatio
Externí odkaz:
https://doaj.org/article/38ddac8907fe4c9396348575d513d667
Autor:
Michael Uckelmann, Vita Levina, Cyntia Taveneau, Xiao Han Ng, Varun Pandey, Qi Zhang, Sarena Flanigan, Minrui Li, Partha Pratim Das, Alex de Marco, Chen Davidovich
The compaction of chromatin is a prevalent paradigm in gene repression. Chromatin compaction is commonly thought to repress transcription by restricting chromatin accessibility. However, the spatial organisation and dynamics of chromatin compacted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94bb686c987a9dd853d38ccd7564f747
https://doi.org/10.1101/2023.05.08.539931
https://doi.org/10.1101/2023.05.08.539931
Autor:
Patrick Cleeve, David Dierickx, Genevieve Buckley, Sergey Gorelick, Lucile Naegele, Lachlan Burne, James C Whisstock, Alex de Marco
Automation in microscopy is the key to success in long and complex experiments. Most microscopy manufacturers provide Application Programming Interfaces (API) to enable communication between a user-defined program and the hardware. Although APIs effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7349b390ef2bbfafe099290a93b31d47
https://doi.org/10.1101/2022.11.01.514681
https://doi.org/10.1101/2022.11.01.514681