Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Alex, Yaroshinsky"'
Autor:
Emerson C. Perin, Kenneth M. Borow, Timothy D. Henry, Farrell O. Mendelsohn, Leslie W. Miller, Elizabeth Swiggum, Eric D. Adler, David H. Chang, R. David Fish, Alain Bouchard, Margaret Jenkins, Alex Yaroshinsky, Jack Hayes, Olga Rutman, Christopher W. James, Eric Rose, Silviu Itescu, Barry Greenberg
Publikováno v:
Journal of the American College of Cardiology. 81:849-863
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4465a741262ed27d5c50f9cad4bd5eda
https://doi.org/10.1016/j.jacc.2022.11.061
https://doi.org/10.1016/j.jacc.2022.11.061
Autor:
Hee Jin Kim, Grace Kimmel, Jennifer Bares, Soo Jung Kim, Giselle Singer, Alex Yaroshinsky, Margot Chima, Mark Lebwohl, Jerry Bagel
Publikováno v:
SKIN The Journal of Cutaneous Medicine. 5:524-529
Background: Brodalumab is an interleukin-17 receptor A antagonist approved for the treatment of moderate-to-severe plaque psoriasis. Our prior publication reported significant disease improvement with brodalumab in psoriasis patients who had previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3884d555f30857c4e21315e828bcaa
https://doi.org/10.25251/skin.5.5.10
https://doi.org/10.25251/skin.5.5.10
Autor:
Sean Oosterholt, Oscar Della Pasqua, Tiago Gomes, Stuart Evans, Mike Snape, Hanns Lochmüller, Nikoletta Nikolenko, Joseph P. Horrigan, Alison McMorn, Alex Yaroshinsky
Publikováno v:
Pediatric Neurology. 112:84-93
GSK3β is an intracellular regulatory kinase that is dysregulated in multiple tissues in type 1 myotonic dystrophy, a rare neuromuscular disorder that manifests at any age. AMO-02 (tideglusib) inhibits GSK3β activity in preclinical models of type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282a4c2a5b9c06c41553fab7a003353b
https://doi.org/10.1016/j.pediatrneurol.2020.08.001
https://doi.org/10.1016/j.pediatrneurol.2020.08.001
Autor:
Pearl Grimes, Jag Bhawan, Michael Howell, Seemal Desai, Edna Coryell, Michael Einziger, Ann Simpson, Alex Yaroshinsky, Tim McCraw
Publikováno v:
Journal of drugs in dermatology : JDD. 21(2)
Malassezin is a natural indole compound produced by the fungus Malassezia furfur and preclinical investigations have demonstrated an ability to suppress melanogenesis.To investigate the histopathological effects of malassezin for treatment of facial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9b2c04fcbf71567451ab4571be5586
https://pubmed.ncbi.nlm.nih.gov/35133118
https://pubmed.ncbi.nlm.nih.gov/35133118
Autor:
Seemal R. Desai, Ann Marie Simpson, Alex Yaroshinsky, Jag Bhawan, Michael Einziger, Michael D. Howell, Tim McCraw, Pearl E. Grimes, Rama Nashawati, Edna Coryell
Publikováno v:
Journal of the American Academy of Dermatology. 87(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13cad7282a78d08627f781f3355ea79
https://pubmed.ncbi.nlm.nih.gov/34678236
https://pubmed.ncbi.nlm.nih.gov/34678236
Publikováno v:
Circulation Research. 125:265-281
Advanced heart failure (HF) is a progressive disease characterized by recurrent hospitalizations and high risk of mortality. Indeed, outcomes in late stages of HF approximate those seen in patients with various aggressive malignancies. Clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51577299ba18f175dc2ba557404a08a
https://doi.org/10.1161/circresaha.119.314951
https://doi.org/10.1161/circresaha.119.314951
Autor:
Elizabeth Berry-Kravis, Joseph P. Horrigan, Nicole Tartaglia, Randi Hagerman, Alexander Kolevzon, Craig A. Erickson, Shivkumar Hatti, Mike Snape, Alex Yaroshinsky, George Stoms, Larry Glass, Nancy E. Jones, Kevin Sanders, Jean Frazier, Thomas Challman, Jeffrey Innis, Bryan King, Joseph Cubells, Jeannie Visootsak, Steven Skinner, Dianne Treadwell-Deering, Sherry Sellers Vinson, Howard Needelman
Publikováno v:
Pediatric neurology. 110
We analyze the safety and tolerability of trofinetide and provide a preliminary evaluation of its efficacy in adolescent and adult males with fragile X syndrome.This study was an exploratory, phase 2, multicenter, double-blind, placebo-controlled, pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f4738de28601a3919712ffd01832dd
https://pubmed.ncbi.nlm.nih.gov/32660869
https://pubmed.ncbi.nlm.nih.gov/32660869
Publikováno v:
Statistics in Medicine
This paper considers the analysis of a repeat event outcome in clinical trials of chronic diseases in the context of dependent censoring (e.g. mortality). It has particular application in the context of recurrent heart failure hospitalisations in tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d69cabf72ae3fe3665055433d5df41
https://ora.ox.ac.uk/objects/uuid:e6873d7c-bbde-49bc-aaeb-9e93a88ef54f
https://ora.ox.ac.uk/objects/uuid:e6873d7c-bbde-49bc-aaeb-9e93a88ef54f
Publikováno v:
Circulation research. 125(3)
Advanced heart failure (HF) is a progressive disease characterized by recurrent hospitalizations and high risk of mortality. Indeed, outcomes in late stages of HF approximate those seen in patients with various aggressive malignancies. Clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5db3fef07f0704befbe9d59422c22d5c
https://pubmed.ncbi.nlm.nih.gov/31415229
https://pubmed.ncbi.nlm.nih.gov/31415229
Autor:
David H, McDaniel, Jacob M, Waugh, Lily I, Jiang, Thomas J, Stephens, Alex, Yaroshinsky, Chris, Mazur, Mitchell, Wortzman, Diane B, Nelson
Objectives: Investigators sought to evaluate the antioxidant capacity of a comprehensive topical antioxidant (WEL-DS), its ability to protect skin against the oxidizing effects of UVA/UVB radiation, and to assess the effectiveness and tolerability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c07c834e979782e8aaa3fef984bc3588
https://europepmc.org/articles/PMC6508483/
https://europepmc.org/articles/PMC6508483/