Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alex, Whittington"'
Autor:
Ekaterina Shatalina, Thomas S. Whitehurst, Ellis Chika Onwordi, Barnabas J. Gilbert, Gaia Rizzo, Alex Whittington, Ayla Mansur, Hideo Tsukada, Tiago Reis Marques, Sridhar Natesan, Eugenii A. Rabiner, Matthew B. Wall, Oliver D. Howes
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background Mitochondrial function plays a key role in regulating neurotransmission and may contribute to general intelligence. Mitochondrial complex I (MC-I) is the largest enzyme of the respiratory chain. Recently, it has become possible to
Externí odkaz:
https://doaj.org/article/fc9cc9db83404d56a6bdf9ac805e11dd
Autor:
Ashwin V. Venkataraman, Wenjia Bai, Alex Whittington, James F. Myers, Eugenii A. Rabiner, Anne Lingford-Hughes, Paul M. Matthews, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2021)
Abstract Background Amyloid-β (Aβ) PET has emerged as clinically useful for more accurate diagnosis of patients with cognitive decline. Aβ deposition is a necessary cause or response to the cellular pathology of Alzheimer’s disease (AD). Usual c
Externí odkaz:
https://doaj.org/article/232b9cbd125145b38e07fa18b48eaefd
Autor:
Azadeh Firouzian, Alex Whittington, Graham E. Searle, Ivan Koychev, Giovanna Zamboni, Simon Lovestone, Roger N. Gunn, on behalf of the Deep and Frequent Phenotyping study team
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Background AD is a progressive neurodegenerative disorder that is associated with the accumulation of two different insoluble protein aggregates, Aβ plaques and hyperphosphorylated tau. This study aimed to investigate the optimal acquisitio
Externí odkaz:
https://doaj.org/article/c6955bff955c4b8daa4b716c80fc264e
Autor:
John P. Seibyl, Jonathan M. DuBois, Annie Racine, Jessica Collins, Qi Guo, Dustin Wooten, Eddie Stage, David Cheng, Roger N. Gunn, Lilly Porat, Alex Whittington, Phillip H. Kuo, Masanori Ichise, Robert Comley, Laurent Martarello, Cristian Salinas
Publikováno v:
Journal of Nuclear Medicine. 64:444-451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c35f07b9463ac70c5305d80d946362e
https://doi.org/10.2967/jnumed.122.264371
https://doi.org/10.2967/jnumed.122.264371
Autor:
Amy E. Jolly, Vanessa Raymont, James H. Cole, Alex Whittington, Gregory Scott, Sara De Simoni, Graham Searle, Roger N. Gunn, David J. Sharp
Publikováno v:
NeuroImage: Clinical, Vol 24, Iss , Pp - (2019)
Objective: To investigate dopamine D2/D3 receptor availability following traumatic brain injury (TBI) and their relationship to the presence of DSM-IV Major Depressive Disorder (MDD) and patterns of axonal injury. Methods: Twelve moderate-severe TBI
Externí odkaz:
https://doaj.org/article/ef8c16a9ac5c4e5aac92a07ffa9144e5
Autor:
Renaud Lhommel, Alex Whittington, Cyrille Sur, José Luis Molinuevo, Vincent Dore, Irina Savitcheva, Juan Domingo Gispert, Bernard Hanseeuw, Gill Farrar, Christopher C. Rowe, Gemma Salvadó, Lyduine E. Collij, Mahnaz Shekari, Agneta Nordberg, Christopher Buckley, Roger N. Gunn, Marco Bucci, Oskar Hansson
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:2183-2199
Background [18F]flutemetamol PET scanning provides information on brain amyloid load and has been approved for routine clinical use based upon visual interpretation as either negative (equating to none or sparse amyloid plaques) or amyloid positive (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258c8b489084dc4f6ac86375c2dea356
https://doi.org/10.1007/s00259-021-05311-5
https://doi.org/10.1007/s00259-021-05311-5
Autor:
John P, Seibyl, Jonathan M, DuBois, Annie, Racine, Jessica, Collins, Qi, Guo, Dustin, Wooten, Eddie, Stage, David, Cheng, Roger N, Gunn, Lilly, Porat, Alex, Whittington, Phillip H, Kuo, Masanori, Ichise, Robert, Comley, Laurent, Martarello, Cristian, Salinas
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa196437beb9662fb6b463df52703cdd
https://pubmed.ncbi.nlm.nih.gov/36175137
https://pubmed.ncbi.nlm.nih.gov/36175137
Nonlinear biomarker interactions in conversion from mild cognitive impairment to Alzheimer's disease
Autor:
Paul M. Matthews, James H. Cole, Alex Whittington, Ben Glocker, David J. Sharp, Sebastian G. Popescu, Roger N. Gunn
Publikováno v:
Human Brain Mapping
Multiple biomarkers can capture different facets of Alzheimer's disease. However, statistical models of biomarkers to predict outcomes in Alzheimer's rarely model nonlinear interactions between these measures. Here, we used Gaussian Processes to addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d826ce321fdfc391b6978aef0a320f2
https://doi.org/10.1002/hbm.25133
https://doi.org/10.1002/hbm.25133
Autor:
Alex Whittington, Roger N. Gunn
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a10a90f98e751f509990f367171d09d8
https://doi.org/10.1002/alz.056191
https://doi.org/10.1002/alz.056191
Autor:
Roger N. Gunn, Alex Whittington
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ec41b43802164a0369fca3f75e236a0
https://doi.org/10.1002/alz.045957
https://doi.org/10.1002/alz.045957