Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Alex, Howard"'
Autor:
Lydia Flett, Radwa Abdelatif, Sarah Akhtar Baz, Samantha Brady, Belén Corbacho, Kate Common, Abbie Cowling, Caroline Fairhurst, Ellie Fitzmaurice, Shreyans Gandhi, Andrea Hilton, William Hope, Alex Howard, Joanne Laycock, Patrick Lillie, Gemma Mitchell, Adwoa Parker, Mary Peel, Laura Sheard, Jacqueline Sneddon, Thomas Taynton, Puvan Tharmanathan, David Torgerson, Han-I Wang, David Allsup, Gavin Barlow
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Acute leukaemias (AL) are life-threatening blood cancers that can be potentially cured with treatment involving myelosuppressive, multiagent, intensive chemotherapy (IC). However, such treatment is associated with a risk of seriou
Externí odkaz:
https://doaj.org/article/d5e78be4af574ce5bfc285fc48d4a353
Autor:
Bridget Young, Lance Turtle, Stephen Aston, Ashley P Jones, Alex Howard, Dan G Wootton, Stephanie Willshaw, Frances Sherratt, Natalia Shafiqa, Simon Abrams, Anica Alvarez Nishio
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction Non-ventilator-associated hospital-acquired pneumonia (nv-HAP) is the most common healthcare-associated infection (HCAI), is associated with high mortality and morbidity and places a major burden on healthcare systems. Diagnosis currentl
Externí odkaz:
https://doaj.org/article/249b963ef12f40d38d2c2c257122b294
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTEffective policy to address the global threat of antimicrobial resistance requires robust antimicrobial susceptibility data. Traditional methods for measuring minimum inhibitory concentration (MIC) are resource intensive, subject to human err
Externí odkaz:
https://doaj.org/article/baea3318d0d94c31867716815bd4c64f
Autor:
Conor Rosato, Peter L. Green, John Harris, Simon Maskell, William Hope, Alessandro Gerada, Alex Howard
Publikováno v:
IEEE Access, Vol 12, Pp 100772-100791 (2024)
Antimicrobial resistance (AMR) emerges when disease-causing microorganisms develop the ability to withstand the effects of antimicrobial therapy. This phenomenon is often fueled by the human-to-human transmission of pathogens and the overuse of antib
Externí odkaz:
https://doaj.org/article/82f66a11f6b74de1a6f6802b1cbb98df
Autor:
Rachel J. Husband, Cornelius Strohm, Karen Appel, Orianna B. Ball, Richard Briggs, Johannes Buchen, Valerio Cerantola, Stella Chariton, Amy L. Coleman, Hyunchae Cynn, Dana Dattelbaum, Anand Dwivedi, Jon H. Eggert, Lars Ehm, William J. Evans, Konstantin Glazyrin, Alexander F. Goncharov, Heinz Graafsma, Alex Howard, Larissa Huston, Trevor M. Hutchinson, Huijeong Hwang, Sony Jacob, Johannes Kaa, Jaeyong Kim, Minseob Kim, Egor Koemets, Zuzana Konôpková, Falko Langenhorst, Torsten Laurus, Xinyang Li, Jona Mainberger, Hauke Marquardt, Emma E. McBride, Christopher McGuire, James D. McHardy, Malcolm I. McMahon, R. Stewart McWilliams, Alba S. J. Méndez, Anshuman Mondal, Guillaume Morard, Earl F. O'Bannon, Christoph Otzen, Charles M. Pépin, Vitali B. Prakapenka, Clemens Prescher, Thomas R. Preston, Ronald Redmer, Michael Roeper, Carmen Sanchez-Valle, Dean Smith, Raymond F. Smith, Daniel Sneed, Sergio Speziale, Tobias Spitzbart, Stephan Stern, Blake T. Sturtevant, Jolanta Sztuk-Dambietz, Peter Talkovski, Nenad Velisavljevic, Cara Vennari, Zhongyan Wu, Choong-Shik Yoo, Ulf Zastrau, Zsolt Jenei, Hanns-Peter Liermann
Publikováno v:
Journal of Synchrotron Radiation, Vol 30, Iss 4, Pp 671-685 (2023)
An experimental platform for dynamic diamond anvil cell (dDAC) research has been developed at the High Energy Density (HED) Instrument at the European X-ray Free Electron Laser (European XFEL). Advantage was taken of the high repetition rate of the E
Externí odkaz:
https://doaj.org/article/e8503fe0db1d4e95aaaebc8380438e1f
Autor:
Alex Howard, William Hope
Publikováno v:
Journal of Fungi, Vol 9, Iss 2, p 192 (2023)
Pharmacokinetic-pharmacodynamic (PK-PD) analysis is of central importance to the progress of an antifungal agent into clinical use. It is crucial to ensure that preclinical studies give the best possible prediction of the way drugs are likely to beha
Externí odkaz:
https://doaj.org/article/2290d2c39be849ca8349c0b0bb971aef
Autor:
Alasdair T. M. Hubbard, Jenifer Mason, Paul Roberts, Christopher M. Parry, Caroline Corless, Jon van Aartsen, Alex Howard, Issra Bulgasim, Alice J. Fraser, Emily R. Adams, Adam P. Roberts, Thomas Edwards
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
An E. coli and K. pneumoniae phenotype resistant to piperacillin/tazobactam has recently emerged. Here, the authors show that hyperproduction of the β-lactamase driving this resistance occurs due to excision and reinsertion of a translocatable unit
Externí odkaz:
https://doaj.org/article/49781534e05f4b11946b910dc6606509
Publikováno v:
The Lancet Infectious Diseases. 23:405-406
Autor:
Alex Howard, William Hope
Publikováno v:
JAC-antimicrobial resistance. 4(4)
Primary antifungal chemoprophylaxis (PAC) is the widespread strategy of choice for the prevention of invasive fungal disease in patients with acute leukaemia (AL). Twice-weekly monitoring of the serum biomarkers (SBM) galactomannan and 1,3-β-d-gluca