Zobrazeno 1 - 10 of 52 pro vyhledávání: '"Alex, Hodge"'
1
Akademický článek
AKT/mTOR signaling modulates resistance to endocrine therapy and CDK4/6 inhibition in metastatic breast cancers
Autor: Maysa M. Abu-Khalaf, K. Alex Hodge, Christos Hatzis, Elisa Baldelli, Emna El Gazzah, Frances Valdes, William M. Sikov, Monica M. Mita, Neelima Denduluri, Rita Murphy, Daniel Zelterman, Lance Liotta, Bryant Dunetz, Rick Dunetz, Emanuel F. Petricoin, Mariaelena Pierobon
Publikováno v: npj Precision Oncology, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract Endocrine therapy (ET) in combination with CDK4/6 inhibition is routinely used as first-line treatment for HR+/HER2− metastatic breast cancer (MBC) patients. However, 30–40% of patients quickly develop disease progression. In this open-l
Externí odkaz: https://doaj.org/article/c34fa79216b44a448f600ad8e158ac17
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2
Akademický článek
Addressing the liver progenitor cell response and hepatic oxidative stress in experimental non-alcoholic fatty liver disease/non-alcoholic steatohepatitis using amniotic epithelial cells
Autor: Mihiri Goonetilleke, Nathan Kuk, Jeanne Correia, Alex Hodge, Gregory Moore, Michael P. Gantier, George Yeoh, William Sievert, Rebecca Lim
Publikováno v: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Non-alcoholic fatty liver disease is the most common liver disease globally and in its inflammatory form, non-alcoholic steatohepatitis (NASH), can progress to cirrhosis and hepatocellular carcinoma (HCC). Currently, patient educa
Externí odkaz: https://doaj.org/article/e6d6b91ca0be446bbc2ca67bfcc4f68e
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4
Akademický článek
An exploratory study examining how nano-liquid chromatography–mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease
Autor: Zobair M. Younossi, Azza Karrar, Mariaelena Pierobon, Aybike Birerdinc, Maria Stepanova, Dinan Abdelatif, Zahra Younoszai, Thomas Jeffers, Sean Felix, Kianoush Jeiran, Alex Hodge, Weidong Zhou, Fanny Monge, Lakshmi Alaparthi, Vikas Chandhoke, Zachary D. Goodman, Emanuel F. Petricoin
Publikováno v: BMC Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Non-alcoholic steatohepatitis (NASH) is among the leading causes of liver disease worldwide. It is increasingly recognized that the phenotype of NASH may involve a number of different pathways, of which each could become important
Externí odkaz: https://doaj.org/article/7f7defeded5b4a4cbe23233ca72ace90
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5
Akademický článek
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6
Abstract P2-07-05: Activation of the AKT/mTOR signaling pathway is associated with response to the combination of endocrine therapy and CDK4/6 inhibitor in HR+/HER2- metastatic breast cancer
Autor: Maysa Abu-Khalaf, Christos Hatzis, K. Alex Hodge, Elisa Baldelli, William Sikov, Monica Mita, Frances Valdes-Albini, Bryant Dunetz, Emanuel Petricoin, Mariaelena Pierobon
Publikováno v: Cancer Research. 82:P2-07
Background: As part of a multicenter study designed to identify markers of response or resistance to the combination of endocrine therapy (ET) and a cyclin dependent kinase 4/6 inhibitor (CDK 4/6i) as standard 1st-line therapy in patients with hormon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c726a776d879d3edb25dc25188d860c6
https://doi.org/10.1158/1538-7445.sabcs21-p2-07-05
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