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CYP2C9 and VKORC1 genotyping for the quality of long-standing warfarin treatment in Russian patients
Autor:
A. B. Dobrovolsky, Galina Lifshits, Tatyana Vavilova, Kropacheva Es, Alevtina Grontkovskaya, Titaeva Ev, Olga V. Sirotkina, Irina Galkina, Dmitry Zateyshchikov, Elizaveta Panchenko, Lyudmila Grehova, O A Zemlyanskaya, Dmitry Trofimov, Nadezda Vorobyeva, Sergey Sinitsin, Irina Zotova, Natalya Vereina
Publikováno v:
The Pharmacogenomics Journal. 20:687-694
A total of 263 warfarin naive patients with indications to long-term anticoagulation were included in prospective multicenter study and randomized into Pharmacogenetics and Standard dosing groups. The loading warfarin dose in Pharmacogenetics group w