Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alevtina Grishanova"'
Autor:
Maria Perepechaeva, Anastasia Studenikina, Andrew Proskura, Alevtina Grishanova, Alexander Autenshlyus
Breast tumours comprise a wide range of disorders requiring different and often personalised treatment plans. The microRNA levels indicating the regulation of gene expression involved in oncogenesis can serve as diagnostic and prognostic biomarkers o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b32339af0f01ead559beb28174cc4435
https://doi.org/10.21203/rs.3.rs-2299018/v1
https://doi.org/10.21203/rs.3.rs-2299018/v1
Publikováno v:
International journal of molecular sciences. 23(12)
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a ligand-activated transcription factor necessary for the launch of transcr
Publikováno v:
Europe PubMed Central
The authors' rat experiments have shown that inhibition of pro-oxidant reactions in hepatocyte microsomal fraction in response to hepatic exposure to low-intensive IR-laser radiation and low-intensity ultrasound combines with multidirectional action
Publikováno v:
Europe PubMed Central
The activity changes of cytochrome P-450-dependent monooxygenases of hepatic microsomal fraction were studied in, experimental animals after prolonged application (1 month) of low radiation doses (0.258 mkl/kg). The obtained results show the increase
Publikováno v:
Europe PubMed Central
The experiments on 130 rat males have shown that the exposure of the animals' liver to centimeter microwaves enhances catalytic activity of P-450p cytochrome, an enzyme of drug microsomal metabolism. However, changes in pharmacokinetic parameters of
Publikováno v:
Europe PubMed Central
Perfluorooctylbromide (PFOB), a constituent component of gas-transporting fluorocarbon emulsions, liberates bromide ions when PFOB undergoes NADPH-dependent metabolism by liver microsomal monooxygenase. The PFOB emulsion injected to rats decreases th
Publikováno v:
Europe PubMed Central
Effects of pyridine and pyridine-N-oxide on the monooxygenase system of rat liver microsomes have been studied. Pyridine (200 mg/kg) increased total cytochrome P-450 content and activated metabolism of some specific substrates 24 hours after injectio
Publikováno v:
Europe PubMed Central
The inducer of the liver monooxygenase system perfluorodecalin added to microsomes as a submicron emulsion forms an enzyme-substrate complex with cytochrome P-450. The K(app) values for the perfluorodecalin binding to cytochrome P-450 in microsomes i
Autor:
Ta, Zolotareva, Ga, Gorchakova, Vl, Konovalenko, Ln, Konovalenko, Alevtina Grishanova, Lf, Guliaeva, Vv, Liakhovich
Publikováno v:
Europe PubMed Central
In experiments on male Wistar rats it has been found that physical factors applied in medicine (laser radiation of low intensity with wave length 0.89 microns, microwaves of centimeter range of 2450 MHz, and ultrasound of low intensity 880 KHz) chang
Publikováno v:
Europe PubMed Central
The synthesis of pharmacologically active diazepam metabolites (oxazepam, 4-hydroxydiazepam, N-demethyldiazepam) in liver microsomes of intact and phenobarbital-, 3-methylcholanthrene- and dexamethasone-induced male and female Wistar rats as well as