Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alevtina Domashenko"'
Publikováno v:
Nature Biotechnology. 18:420-423
The topical delivery of transgenes to hair follicles has potential for treating disorders of the skin and hair. Here we show that the topical administration of liposome-DNA mixtures (lipoplex) to mouse skin and to human skin xenografts resulted in ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32511cc51f5fd9c333d258335fea26c0
https://doi.org/10.1038/74480
https://doi.org/10.1038/74480
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799792
The clinical potential of therapeutic quantities of primary hematopoietic cells, either unmodified or altered via genetic modification, has stimulated the search for techniques that allow the production of large numbers of hematopoietic precursors, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd8a14040dcd588d78011d3b86ee619
https://doi.org/10.1007/978-1-61779-980-8_23
https://doi.org/10.1007/978-1-61779-980-8_23
Publikováno v:
Blood. 116(15)
Retroviral overexpression of NF-Ya, the regulatory subunit of the transcription factor NF-Y, activates the transcription of multiple genes implicated in hematopoietic stem cell (HSC) self-renewal and differentiation and directs HSCs toward self-renew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213481839b72b59941ecf35eb7bb3153
https://pubmed.ncbi.nlm.nih.gov/20616221
https://pubmed.ncbi.nlm.nih.gov/20616221
Autor:
Nicole R. Cunningham, Jenni A. Punt, Carson Wills, Stephen G. Emerson, Kaitlyn Shank, Alevtina Domashenko, Russell Garrett, Yusup Shin
Publikováno v:
Blood. 118:3394-3394
Abstract 3394 Hematopoietic stem cells (HSC) replenish the cellular components of the blood throughout life by a homeostatic process in which the majority of HSCs remain quiescent while a small percentage enter the cell cycle to either self-review or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc37ccb06d012c2c1f9135c63e830a1
https://doi.org/10.1182/blood.v118.21.3394.3394
https://doi.org/10.1182/blood.v118.21.3394.3394
Autor:
Gerd Bungartz, Stephen G. Emerson, Alevtina Domashenko, Asia Gobourne, Heidi S. Bretscher, Russell Garrett
Publikováno v:
Blood. 114:3635-3635
Abstract 3635 Poster Board III-571 Nonparenchymal stromal cells form the cellular constituents of tissue-specific stem cell niches. One key question in stem cell biology is the nature of signals provided by stromal cells in general, and via stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dc927d142695cc122860026dec5a27a
https://doi.org/10.1182/blood.v114.22.3635.3635
https://doi.org/10.1182/blood.v114.22.3635.3635
Publikováno v:
Blood. 114:2504-2504
Abstract 2504 Poster Board II-481 Polyinosinic:polycytidlyic acid (poly I:C) is a synthetic double-stranded RNA used to mimic viral infections in order to study immune responses and to activate gene deletion in lox-p systems employing a Cre gene resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4934ccd5cf41bfc4c53a5002b98f0f73
https://doi.org/10.1182/blood.v114.22.2504.2504
https://doi.org/10.1182/blood.v114.22.2504.2504
Publikováno v:
Blood. 112:3528-3528
Protein transduction offers great promise for clinical applications as a safe alternative to viral gene delivery. We have previously shown that NF-YA transcription factor which regulates the expression of several genes implicated in hematopoietic ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::149fa310e3399de0601309abb63fb3d9
https://doi.org/10.1182/blood.v112.11.3528.3528
https://doi.org/10.1182/blood.v112.11.3528.3528
Publikováno v:
Blood. 106:4253-4253
We have recently found that the trimeric transcription factor NF-Y is a direct stimulator of hematopoietic stem cell (HSC) renewal, activating the transcription of several genes involved in HSC self-renewal and differentiation including the Hox4 para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6585ce43cbfafdb49556659d23562b
https://doi.org/10.1182/blood.v106.11.4253.4253
https://doi.org/10.1182/blood.v106.11.4253.4253
Publikováno v:
Blood. 104:3542-3542
Protein transduction to redirect hematopoietic stem cell (HSC) fate for clinical therapy is an attractive alternative to genetic modification, in that the stem cell genome is not permanently modified. Indeed, published studies suggest that protein tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1c966a3510a55d4ad383b0c07af99da
https://doi.org/10.1182/blood.v104.11.3542.3542
https://doi.org/10.1182/blood.v104.11.3542.3542