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of 5
pro vyhledávání: '"Alev Cagla Ozdemir"'
Autor:
Alev Cagla Ozdemir, Grace M Wynn, Aimee Vester, M Neale Weitzmann, Gretchen N Neigh, Shanthi Srinivasan, M Katharine Rudd
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188763 (2017)
The G-protein beta subunit 3 (GNB3) gene has been implicated in obesity risk; however, the molecular mechanism of GNB3-related disease is unknown. GNB3 duplication is responsible for a syndromic form of childhood obesity, and an activating DNA sequen
Externí odkaz:
https://doaj.org/article/6377138046d049ce892d693e55016244
Autor:
Shanthi Srinivasan, M. Neale Weitzmann, Alev Cagla Ozdemir, Grace M. Wynn, M. Katharine Rudd, Gretchen N. Neigh, Aimee Vester
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188763 (2017)
PLoS ONE
PLoS ONE
The G-protein beta subunit 3 (GNB3) gene has been implicated in obesity risk; however, the molecular mechanism of GNB3-related disease is unknown. GNB3 duplication is responsible for a syndromic form of childhood obesity, and an activating DNA sequen
Autor:
Ian S. Goldlust, Jay W. Ellison, Rebecca Cozad, Madhuri Hegde, Jill A. Rosenfeld, Karen N. Conneely, Karen Hermetz, M. Katharine Rudd, Alev Cagla Ozdemir, Lisa M. Catalano, Laurie A. Demmer, Erik C. Thorland, Brad Angle, Jennifer G. Mulle, Blake C. Ballif, Richard Barfield, Alison Colley, Lisa G. Shaffer, Grace M. Wynn, Katherine H. Kim, Amy E Webb, Shikha Dharamrup
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(37)
Obesity is a highly heritable condition and a risk factor for other diseases, including type 2 diabetes, cardiovascular disease, hypertension, and cancer. Recently, genomic copy number variation (CNV) has been implicated in cases of early onset obesi
Copy number variants (CNVs) are widely distributed throughout the human genome, where they contribute to genetic variation and phenotypic diversity. Spontaneous CNVs are also a major cause of genetic and developmental disorders and arise frequently i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9eb465ece9513a63c2cdb4b62db49ef
https://europepmc.org/articles/PMC3198378/
https://europepmc.org/articles/PMC3198378/
Autor:
Thomas E. Wilson, Shanda R. Birkeland, Robert H. Lyons, Martin F. Arlt, Alev Cagla Ozdemir, Thomas W. Glover
Publikováno v:
Genetics. 187(3)
Copy-number variants (CNVs) are a major source of genetic variation in human health and disease. Previous studies have implicated replication stress as a causative factor in CNV formation. However, existing data are technically limited in the quality