Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Aletta M"'
Autor:
Aletta M. R. van den Bosch, Marlijn van der Poel, Nina L. Fransen, Maria C. J. Vincenten, Anneleen M. Bobeldijk, Aldo Jongejan, Hendrik J. Engelenburg, Perry D. Moerland, Joost Smolders, Inge Huitinga, Jörg Hamann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Microglia nodules (HLA-DR+ cell clusters) are associated with brain pathology. In this post-mortem study, we investigated whether they represent the first stage of multiple sclerosis (MS) lesion formation. We show that microglia nodules are
Externí odkaz:
https://doaj.org/article/598c1f7d0a794ef3b7096efd7cbff052
Autor:
Aletta M. E. Millen, Tshiamo T. Maluleke, Leandrie Pienaar, Farhanah N. Sallie, Radhini Veerappan, Per E. Andrén, Sooraj Baijnath
Publikováno v:
Biology, Vol 13, Iss 7, p 516 (2024)
Background: The effects of collagen-induced arthritis (CIA), a model of systemic inflammation, on brain regional molecular markers associated with neurological disorders are uncertain. Objective: This study investigated the brain regional molecular c
Externí odkaz:
https://doaj.org/article/73b186ffd3f44d99ba19a57e45c849ff
Autor:
Ashmeetha Manilall, Lebogang Mokotedi, Sulè Gunter, Regina Le Roux, Serena Fourie, Colleen A. Flanagan, Aletta M. E. Millen
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Titin phosphorylation contributes to left ventricular (LV) diastolic dysfunction. The independent effects of inflammation on the molecular pathways that regulate titin phosphorylation are unclear. Methods We investigated the effec
Externí odkaz:
https://doaj.org/article/73f4db01916a4900874dfedfb2989ff8
Autor:
Aletta M. Moll
Publikováno v:
African Journal of Disability, Vol 12, Iss 0, Pp e1-e11 (2023)
Background: South African legislation promotes the accommodation of employees with disabilities through enabling modifications and adjustments in the workplace. The literature about the experiences of employees with disabilities in higher education e
Externí odkaz:
https://doaj.org/article/87489c2491a5454fb129cd58ffcf8b87
Autor:
Sulè Gunter, Frederic S Michel, Serena S Fourie, Mikayra Singh, Regina le Roux, Ashmeetha Manilall, Lebogang P Mokotedi, Aletta M E Millen
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264558 (2022)
Chronic inflammation causes dysregulated expression of microRNAs. Aberrant microRNA expression is associated with endothelial dysfunction. In this study we determined whether TNF-α inhibition impacted the expression of miRNA-146a-5p and miRNA-155-5p
Externí odkaz:
https://doaj.org/article/38944472a26848d9bfac0d26f732980a
Autor:
Lebogang Mokotedi, Frederic S Michel, Conrad Mogane, Monica Gomes, Angela J Woodiwiss, Gavin R Norton, Aletta M E Millen
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230657 (2020)
BACKGROUND:High-grade inflammation may play a pivotal role in the pathogenesis of left ventricular (LV) dysfunction. Evidence to support a role of systemic inflammation in mediating impaired LV function in experimental models of rheumatoid arthritis
Externí odkaz:
https://doaj.org/article/f66754cb9d1c493d91a146c639e3a4da
Autor:
Aletta M. Moll, Garfield Bester
Publikováno v:
African Journal of Disability, Vol 8, Iss 0, Pp e1-e8 (2019)
Background: There are multiple factors that make it difficult for learners with a mobility impairment to participate in sport, if not impossible. Unfortunately, it is not known which of these factors can be considered as the most important ones. Obj
Externí odkaz:
https://doaj.org/article/db600dbd300f48cc9cec2f3409278404
Autor:
Lebogang Mokotedi, Sulé Gunter, Chanel Robinson, Gavin R. Norton, Angela J. Woodiwiss, Linda Tsang, Patrick H. Dessein, Aletta M. E. Millen
Publikováno v:
International Journal of Rheumatology, Vol 2017 (2017)
This study compared the estimated prevalence and potential determinants of left ventricular (LV) diastolic dysfunction upon applying different classification criteria in rheumatoid arthritis (RA). LV diastolic function was assessed echocardiographica
Externí odkaz:
https://doaj.org/article/855cf7d0050649fa9b8e2b3ed8f8adc7
Autor:
Patrick H Dessein, Hon-Chun Hsu, Linda Tsang, Aletta M E Millen, Angela J Woodiwiss, Gavin R Norton, Ahmed Solomon, Miguel A Gonzalez-Gay
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121693 (2015)
To determine whether kidney function independently relates to endothelial activation and ultrasound determined carotid atherosclerosis in black and white Africans with rheumatoid arthritis (RA).We calculated the Jelliffe, 5 Cockcroft-Gault equations,
Externí odkaz:
https://doaj.org/article/3bfd03180b804df3a6280fa5d7d41d14
Autor:
Patrick H. Dessein, Linda Tsang, Ahmed Solomon, Angela J. Woodiwiss, Aletta M. E. Millen, Gavin R. Norton
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
In the present study, we examined the potential impact of adiponectin on carotid ultrasound determined atherosclerosis in 210 (119 black and 91 white) RA patients in mixed regression models. Total adiponectin concentrations were smaller in patients w
Externí odkaz:
https://doaj.org/article/403bfa2786704a76aa7c0fc81447d8fe