Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Alethea B Tabor"'
Autor:
Maria D I Manunta, Robin J McAnulty, Aristides D Tagalakis, Stephen E Bottoms, Frederick Campbell, Helen C Hailes, Alethea B Tabor, Geoffrey J Laurent, Christopher O'Callaghan, Stephen L Hart
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26768 (2011)
Gene therapy mediated by synthetic vectors may provide opportunities for new treatments for cystic fibrosis (CF) via aerosolisation. Vectors for CF must transfect the airway epithelium efficiently and not cause inflammation so they are suitable for r
Externí odkaz:
https://doaj.org/article/b4e704dda6444ec3ac8d0e904dd593d2
Autor:
Calogero Tulone, Anne-Marit Sponaas, Eun-Ang Raiber, Alethea B Tabor, Jean Langhorne, Benny M Chain
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24886 (2011)
Merozoite Surface Protein 1 is expressed on the surface of malaria merozoites and is important for invasion of the malaria parasite into erythrocytes. MSP1-specific CD4 T cell responses and antibody can confer protective immunity in experimental mode
Externí odkaz:
https://doaj.org/article/7b58bf8ea2bf4d40afa15c700c3a164a
Autor:
Sarmistha Biswal, Karina Caetano, Diamond Jain, Anusha Sarrila, Tulika Munshi, Rachael Dickman, Alethea B. Tabor, Surya Narayan Rath, Sanjib Bhakta, Anindya S. Ghosh
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 553 (2023)
Class A serine β-lactamases (SBLs) have a conserved non-active site structural domain called the omega loop (Ω-loop), in which a glutamic acid residue is believed to be directly involved in the hydrolysis of β-lactam antibiotics by providing a wat
Externí odkaz:
https://doaj.org/article/681dd803041744f39a53d27fb6efc5d6
Publikováno v:
RSC Chemical Biology. 4:132-137
A new N-terminal tyrosine-containing peptide ligation method has been developed utilising tyrosinase enzymes and a subsequent Pictet-Spengler reaction with aldehydes.
Autor:
Lili Cui, Laila Kudsiova, Frederick Campbell, David J. Barlow, Helen C. Hailes, Alethea B. Tabor, M. Jayne Lawrence
Publikováno v:
Biomaterials Science. 11:3335-3353
Lipopolyplexes formulated from branched cationic peptides with cell receptor targeting sequences, DOTMA and DOPE, and plasmid DNA in the presence of saline form multilamellar nanoparticles with enhanced stability and transfection in serum.
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Peptide toxins that adopt the inhibitory cystine knot (ICK) scaffold have very stable three-dimensional structures as a result of the conformational constraints imposed by the configuration of the three disulfide bonds that are the hallmark of this f
Externí odkaz:
https://doaj.org/article/cbc9457e544e4ab4a814412e0b5ee55b
Autor:
Yugo Tsuchiya, Dominic P. Byrne, Selena G. Burgess, Jenny Bormann, Jovana Baković, Yueyang Huang, Alexander Zhyvoloup, Bess Yi Kun Yu, Sew Peak-Chew, Trang Tran, Fiona Bellany, Alethea B. Tabor, AW Edith Chan, Lalitha Guruprasad, Oleg Garifulin, Valeriy Filonenko, Matthias Vonderach, Samantha Ferries, Claire E. Eyers, John Carroll, Mark Skehel, Richard Bayliss, Patrick A. Eyers, Ivan Gout
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Aurora A kinase is a master mitotic regulator whose functions are controlled by several regulatory interactions and post-translational modifications. It is frequently dysregulated in cancer, making Aurora A inhibition a very attractive antitumor targ
Externí odkaz:
https://doaj.org/article/0b4c8d09c14d4fdebd87d9bb7b34b081
Autor:
Alethea B. Tabor, Matthew H. Todd, Jonathan D. Wilden, H. Britton, Christopher J. Swain, Yuhang Wang, Bethanie A. Clent, Frank Otto
Publikováno v:
Journal of Chemical Education. 98:2899-2905
In response to the closure of many university laboratories due to the Covid-19 pandemic in 2020, a handbook and remote webinar approach designed to support students in the use of software tools for computer-aided drug design has been developed. Speci
Autor:
Helen Allan, Matthias Glaser, Erik Årstad, Robin Bofinger, Gregory Weitsman, Daniel Hochhauser, Tammy L. Kalber, Kerstin Sander, Tony Ng, Rachel Evans, Helen C. Hailes, Alethea B. Tabor
Publikováno v:
Nanoscale. 13:18520-18535
In vivo delivery of small molecule therapeutics to cancer cells, assessment of the selectivity of administration, and measuring the efficacity of the drug in question at the molecule level, are important ongoing challenges in developing new classes o
Autor:
Robin, Bofinger, Gregory, Weitsman, Rachel, Evans, Matthias, Glaser, Kerstin, Sander, Helen, Allan, Daniel, Hochhauser, Tammy L, Kalber, Erik, Årstad, Helen C, Hailes, Tony, Ng, Alethea B, Tabor
Publikováno v:
Nanoscale
In vivo delivery of small molecule therapeutics to cancer cells, assessment of the selectivity of administration, and measuring the efficacity of the drug in question at the molecule level, are important ongoing challenges in developing new classes o