Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Alethea B. Tabor"'
Autor:
Sarmistha Biswal, Karina Caetano, Diamond Jain, Anusha Sarrila, Tulika Munshi, Rachael Dickman, Alethea B. Tabor, Surya Narayan Rath, Sanjib Bhakta, Anindya S. Ghosh
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 553 (2023)
Class A serine β-lactamases (SBLs) have a conserved non-active site structural domain called the omega loop (Ω-loop), in which a glutamic acid residue is believed to be directly involved in the hydrolysis of β-lactam antibiotics by providing a wat
Externí odkaz:
https://doaj.org/article/681dd803041744f39a53d27fb6efc5d6
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Peptide toxins that adopt the inhibitory cystine knot (ICK) scaffold have very stable three-dimensional structures as a result of the conformational constraints imposed by the configuration of the three disulfide bonds that are the hallmark of this f
Externí odkaz:
https://doaj.org/article/cbc9457e544e4ab4a814412e0b5ee55b
Publikováno v:
RSC Chemical Biology. 4:132-137
A new N-terminal tyrosine-containing peptide ligation method has been developed utilising tyrosinase enzymes and a subsequent Pictet-Spengler reaction with aldehydes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8656e0530a8d98da53e9e3bde651547
https://doi.org/10.1039/d2cb00237j
https://doi.org/10.1039/d2cb00237j
Autor:
Lili Cui, Laila Kudsiova, Frederick Campbell, David J. Barlow, Helen C. Hailes, Alethea B. Tabor, M. Jayne Lawrence
Publikováno v:
Biomaterials Science. 11:3335-3353
Lipopolyplexes formulated from branched cationic peptides with cell receptor targeting sequences, DOTMA and DOPE, and plasmid DNA in the presence of saline form multilamellar nanoparticles with enhanced stability and transfection in serum.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f63ae9fbafedca6c3a9c14f46df47495
https://doi.org/10.1039/d2bm01905a
https://doi.org/10.1039/d2bm01905a
Autor:
Yugo Tsuchiya, Dominic P. Byrne, Selena G. Burgess, Jenny Bormann, Jovana Baković, Yueyang Huang, Alexander Zhyvoloup, Bess Yi Kun Yu, Sew Peak-Chew, Trang Tran, Fiona Bellany, Alethea B. Tabor, AW Edith Chan, Lalitha Guruprasad, Oleg Garifulin, Valeriy Filonenko, Matthias Vonderach, Samantha Ferries, Claire E. Eyers, John Carroll, Mark Skehel, Richard Bayliss, Patrick A. Eyers, Ivan Gout
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Aurora A kinase is a master mitotic regulator whose functions are controlled by several regulatory interactions and post-translational modifications. It is frequently dysregulated in cancer, making Aurora A inhibition a very attractive antitumor targ
Externí odkaz:
https://doaj.org/article/0b4c8d09c14d4fdebd87d9bb7b34b081
Autor:
Alethea B. Tabor, Matthew H. Todd, Jonathan D. Wilden, H. Britton, Christopher J. Swain, Yuhang Wang, Bethanie A. Clent, Frank Otto
Publikováno v:
Journal of Chemical Education. 98:2899-2905
In response to the closure of many university laboratories due to the Covid-19 pandemic in 2020, a handbook and remote webinar approach designed to support students in the use of software tools for computer-aided drug design has been developed. Speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb0f2a75904cc1374ed9550bd2ea0845
https://doi.org/10.1021/acs.jchemed.1c00289
https://doi.org/10.1021/acs.jchemed.1c00289
Autor:
Helen Allan, Matthias Glaser, Erik Årstad, Robin Bofinger, Gregory Weitsman, Daniel Hochhauser, Tammy L. Kalber, Kerstin Sander, Tony Ng, Rachel Evans, Helen C. Hailes, Alethea B. Tabor
Publikováno v:
Nanoscale. 13:18520-18535
In vivo delivery of small molecule therapeutics to cancer cells, assessment of the selectivity of administration, and measuring the efficacity of the drug in question at the molecule level, are important ongoing challenges in developing new classes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cf0bfc56ddd371f77f143db3789a24
https://doi.org/10.1039/d1nr02770k
https://doi.org/10.1039/d1nr02770k
Autor:
Robin, Bofinger, Gregory, Weitsman, Rachel, Evans, Matthias, Glaser, Kerstin, Sander, Helen, Allan, Daniel, Hochhauser, Tammy L, Kalber, Erik, Årstad, Helen C, Hailes, Tony, Ng, Alethea B, Tabor
Publikováno v:
Nanoscale
In vivo delivery of small molecule therapeutics to cancer cells, assessment of the selectivity of administration, and measuring the efficacity of the drug in question at the molecule level, are important ongoing challenges in developing new classes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a699473470faaa56cc6a69b3afb54628
https://pubmed.ncbi.nlm.nih.gov/34730152
https://pubmed.ncbi.nlm.nih.gov/34730152
Autor:
Alethea B. Tabor, Eleni Demetriou, Helen C. Hailes, Xavier Golay, Harriet Story, Robin Bofinger
Publikováno v:
The Journal of Physical Chemistry. B
Exogenous chemical exchange saturation transfer (CEST) contrast agents such as glucose or 2-deoxy-d-glucose (2-DG) have shown high sensitivities and significant potential for monitoring glucose uptake in tumors with MRI. Here, we show that liposome e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dae92779589df7000ece9833ea91f84
https://doi.org/10.1021/acs.jpcb.9b02280
https://doi.org/10.1021/acs.jpcb.9b02280
Autor:
Gabriel Waksman, James Sayer, Tina Daviter, Helen Allan, Alethea B. Tabor, Hans Koss, Karin Walldén, Paul J. Gane
Publikováno v:
Journal of peptide science : an official publication of the European Peptide SocietyREFERENCES. 27(10)
Helicobacter pylori (H. pylori) infections have been implicated in the development of gastric ulcers and various cancers: however, the success of current therapies is compromised by rising antibiotic resistance. The virulence and pathogenicity of H.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39433823636b9c46cb0c82f0d102f236
https://pubmed.ncbi.nlm.nih.gov/34142414
https://pubmed.ncbi.nlm.nih.gov/34142414