Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aleta L Svitak"'
Autor:
Jared M. Fine, Jacob Kosyakovsky, Amanda M. Baillargeon, Julian V. Tokarev, Jacob M. Cooner, Aleta L. Svitak, Katherine A. Faltesek, William H. Frey II, Leah R. Hanson
Publikováno v:
Brain and Behavior, Vol 10, Iss 3, Pp n/a-n/a (2020)
Abstract Introduction Intranasal deferoxamine (IN DFO) has been shown to decrease memory loss and have beneficial impacts across several models of neurologic disease and injury, including rodent models of Alzheimer's and Parkinson's disease. Methods
Externí odkaz:
https://doaj.org/article/ddb5a9d4b46347c0abe5269c4f0e207b
Autor:
Bhavani Kashyap, Kathryn A Wyman‐Chick, Leah R Hanson, Samantha J Sherman, Aleta L Svitak, Lauren R O'Keefe, Ella A Chrenka, Michael Edward Sughrue, Michael H Rosenbloom
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4d4eea497a46b3f9806f4fd1afcddd
https://doi.org/10.1002/alz.069325
https://doi.org/10.1002/alz.069325
Autor:
Bhavani Kashyap, William H. Frey, Aleta L. Svitak, Michael H. Rosenbloom, Terry R. Barclay, Lauren R O'Keefe, Leah R. Hanson, Lyndsay M. Hage, Maria Pyle
Publikováno v:
Drugs & Aging. 38:407-415
Intranasal insulin is a potential treatment for neurodegenerative disease shown to increase cerebral glucose uptake, reduce amyloid plaques, and improve verbal memory in cognitively impaired as well as healthy adults. Investigations have suggested ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa283cc7a4d866d1d9071d8def25bfbf
https://doi.org/10.1007/s40266-021-00845-7
https://doi.org/10.1007/s40266-021-00845-7
Autor:
Justin Johnsen, Maria Pyle, Lauren O. Erickson, William H. Frey, Terry R. Barclay, Leah R. Hanson, Michael H. Rosenbloom, Aleta L. Svitak
Publikováno v:
Drugs in R&D, Vol 20, Iss 1, Pp 11-15 (2020)
Drugs in R&D
Drugs in R&D
Background Individuals with Down syndrome are likely to develop clinical and neuropathological brain changes resembling Alzheimer’s disease dementia by the ages of 35–40 years. Intranasal insulin is a potential treatment for neurodegenerative dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1626730e169e3d9c5361695f3521d5
https://doaj.org/article/c289a4a0a4a04de79fa55f27ae5bd12b
https://doaj.org/article/c289a4a0a4a04de79fa55f27ae5bd12b
Autor:
Gunda I. Georg, Usha Mishra, Davin Rautiola, Ronald A. Siegel, Narsihmulu Cheryala, Katherine A. Faltesek, Kathryn M. Nelson, Aleta L. Svitak, Lisa D. Coles, James C. Cloyd, Jared M. Fine, Leah R. Hanson, Patricia D. Maglalang
Publikováno v:
J Pharmacol Exp Ther
Intranasal administration is an attractive route for systemic delivery of small, lipophilic drugs because they are rapidly absorbed through the nasal mucosa into systemic circulation. However, the low solubility of lipophilic drugs often precludes aq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a514524b5e466a79864d86c6410279
https://doi.org/10.1124/jpet.118.255943
https://doi.org/10.1124/jpet.118.255943
Autor:
Aleta L. Svitak, Terry R. Barclay, Lauren O. Erickson, Emily A. Green, William H. Frey, Lyndsay M. Hage, Leah R. Hanson, Michael H. Rosenbloom, Maria Pyle
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c00a1f61eedf638244420dad8ff203
https://doi.org/10.1002/alz.036840
https://doi.org/10.1002/alz.036840
Autor:
Katherine A. Faltesek, Jacob Kosyakovsky, Jared M. Fine, Aleta L. Svitak, Leah R. Hanson, Jacob M. Cooner, Amanda M. Baillargeon, William H. Frey, Julian Tokarev
Publikováno v:
Brain and Behavior
Brain and Behavior, Vol 10, Iss 3, Pp n/a-n/a (2020)
Brain and Behavior, Vol 10, Iss 3, Pp n/a-n/a (2020)
Introduction Intranasal deferoxamine (IN DFO) has been shown to decrease memory loss and have beneficial impacts across several models of neurologic disease and injury, including rodent models of Alzheimer's and Parkinson's disease. Methods In order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff715f913d4f2cac06264b1ef07bf86d
https://doi.org/10.1002/brb3.1536
https://doi.org/10.1002/brb3.1536
Autor:
Aleta L. Svitak, Leah R. Hanson, Bruce A. Witthuhn, Jared M. Fine, William H. Frey, Jacob Kosyakovsky
Publikováno v:
ACS chemical neuroscience. 10(11)
Deferoxamine, a metal chelator, has been shown to be neuroprotective in animal models of ischemic stroke, traumatic brain injury and both subarachnoid and intracerebral hemorrhage. Intranasal deferoxamine (IN DFO) has also shown promise as a potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae8d9f91fc1c3c0e4f57a9f7cb38d5a
https://pubmed.ncbi.nlm.nih.gov/31573798
https://pubmed.ncbi.nlm.nih.gov/31573798
Autor:
Jared M. Fine, Deborah Bingham, Leah R. Hanson, William H. Frey, Aleta L. Svitak, Shyeilla V. Dhuria, S. Scott Panter, Amanda M. Baillargeon, Rachel B. Burns, Abdul N. Kazi
Publikováno v:
Neuroscience Letters. 627:155-159
Hypocretin-1 (HC, orexin-A) is a neuropeptide involved in regulating physiological functions of sleep, appetite and arousal, and it has been shown that intranasal (IN) administration can target HC to the brain. Recent clinical studies have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cbf96d5f9b756f0cbfb9c98245bf18
https://doi.org/10.1016/j.neulet.2016.05.053
https://doi.org/10.1016/j.neulet.2016.05.053
Autor:
Aleta L. Svitak, Michael H. Rosenbloom, Justin Johnsen, Maria Pyle, Leah R. Hanson, Lauren O. Erickson, Terry R. Barclay, William H. Frey
Publikováno v:
Alzheimer's & Dementia. 15:P928-P929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ee645debea13672f7e4195da8844e5
https://doi.org/10.1016/j.jalz.2019.06.3037
https://doi.org/10.1016/j.jalz.2019.06.3037