Non-Tumor Cells within the Tumor Microenvironment—The 'Eminence Grise' of the Glioblastoma Pathogenesis and Potential Targets for Therapy

Autor: Aleksandra S. Bugakova, Daria A. Chudakova, Maria S. Myzina, Elvira P. Yanysheva, Iuliia V. Ozerskaya, Alesya V. Soboleva, Vladimir P. Baklaushev, Gaukhar M. Yusubalieva

Publikováno v: Cells, Vol 13, Iss 10, p 808 (2024)

Glioblastoma (GBM) is the most common malignancy of the central nervous system in adults. GBM has high levels of therapy failure and its prognosis is usually dismal. The phenotypic heterogeneity of the tumor cells, dynamic complexity of non-tumor cel

Externí odkaz: https://doaj.org/article/c2a2be6fe81a4abf9714e448486da513

Multi-Omics Analysis of Glioblastoma Cells’ Sensitivity to Oncolytic Viruses

Autor: Irina Y. Ilina, Dmitry V. Kochetkov, Elizaveta M. Solovyeva, Irina A. Tarasova, Peter M. Chumakov, Alesya V. Soboleva, Pavel Olegovich Vorobyev, Vladimir Gorshkov, George S. Krasnov, Julia A. Bubis, Mikhail V. Gorshkov, Anastasiya V. Lipatova, Sergei A. Moshkovskii, Frank Kjeldsen

Publikováno v: Cancers
Volume 13
Issue 21
Lipatova, A V, Soboleva, A V, Gorshkov, V A, Bubis, J A, Solovyeva, E M, Krasnov, G S, Kochetkov, D V, Vorobyev, P O, Ilina, I Y, Moshkovskii, S A, Kjeldsen, F, Gorshkov, M V, Chumakov, P M & Tarasova, I A 2021, ' Multi-omics analysis of glioblastoma cells’ sensitivity to oncolytic viruses ', Cancers, vol. 13, no. 21, 5268 . https://doi.org/10.3390/cancers13215268
Cancers, Vol 13, Iss 5268, p 5268 (2021)

Simple Summary This study aims to uncover the contribution of interferon-dependent antiviral mechanisms preserved in tumor cells to the resistance of glioblastoma multiforme cells to oncolytic viruses. To characterize the functionality of interferon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575f92813e7d3b2bc0dd20aa0a901513