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Akademický článek

In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene

Autor: Husebye Harald, Nourizadeh-Lillabadi Rasoul, Torgersen Jacob, Aleström Peter

Publikováno v: BMC Genomics, Vol 3, Iss 1, p 25 (2002)

Abstract Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The regulatory mechanisms responsible for brain specificity make the promoter att

Externí odkaz: https://doaj.org/article/0882b6429b054f1b99adf250aff6f316

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Akademický článek

Altered non-coding RNA expression profile in F1 progeny 1 year after parental irradiation is linked to adverse effects in zebrafish

Autor: Leonardo Martín, Jorke H. Kamstra, Selma Hurem, Leif C. Lindeman, Dag A. Brede, Håvard Aanes, Igor Babiak, Amilcar Arenal, Deborah Oughton, Brit Salbu, Jan Ludvig Lyche, Peter Aleström

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

Abstract Gamma radiation produces DNA instability and impaired phenotype. Previously, we observed negative effects on phenotype, DNA methylation, and gene expression profiles, in offspring of zebrafish exposed to gamma radiation during gametogenesis.

Externí odkaz: https://doaj.org/article/13c3e7c8a66640889a25179ca2872f08

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Akademický článek

Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

Autor: Marjo J. den Broeder, Jarle Ballangby, Leonie M. Kamminga, Peter Aleström, Juliette Legler, Leif C. Lindeman, Jorke H. Kamstra

Publikováno v: Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-16 (2020)

Abstract Background Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases. This susceptibility may in part be caused by changes to the epigenetic landscape which consequently aff

Externí odkaz: https://doaj.org/article/0003cd4494f74699ad761b7c77e0dcea

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Akademický článek

Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish

Autor: Jorke H. Kamstra, Selma Hurem, Leonardo Martin Martin, Leif C. Lindeman, Juliette Legler, Deborah Oughton, Brit Salbu, Dag Anders Brede, Jan Ludvig Lyche, Peter Aleström

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

Abstract Ionizing radiation is known to cause DNA damage, yet the mechanisms underlying potential transgenerational effects of exposure have been scarcely studied. Previously, we observed effects in offspring of zebrafish exposed to gamma radiation d

Externí odkaz: https://doaj.org/article/be5bf4d2934f42899d7fd9c93edd5642

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Akademický článek

Gamma radiation induces locus specific changes to histone modification enrichment in zebrafish and Atlantic salmon.

Autor: Leif Christopher Lindeman, Jorke Harmen Kamstra, Jarle Ballangby, Selma Hurem, Leonardo Martín Martín, Dag Anders Brede, Hans Christian Teien, Deborah H Oughton, Brit Salbu, Jan Ludvig Lyche, Peter Aleström

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0212123 (2019)

Ionizing radiation is a recognized genotoxic agent, however, little is known about the role of the functional form of DNA in these processes. Post translational modifications on histone proteins control the organization of chromatin and hence control

Externí odkaz: https://doaj.org/article/4a1ddb464dd9409cad2c7250dc601439

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Akademický článek

Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression.

Autor: Selma Hurem, Leonardo Martín Martín, Dag Anders Brede, Eystein Skjerve, Rasoul Nourizadeh-Lillabadi, Ole Christian Lind, Terje Christensen, Vidar Berg, Hans-Christian Teien, Brit Salbu, Deborah Helen Oughton, Peter Aleström, Jan Ludvig Lyche

Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0179259 (2017)

Ionizing radiation from natural sources or anthropogenic activity has the potential to cause oxidative stress or genetic damage in living organisms, through the ionization and excitation of molecules and the subsequent production of free radicals and

Externí odkaz: https://doaj.org/article/4ee1bec4b55046b6a48f5bcc2c845715

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