Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Alessio Terenzi"'
Autor:
Alessio Terenzi, Mery La Franca, Sushilla van Schoonhoven, Rostyslav Panchuk, Álvaro Martínez, Petra Heffeter, Redding Gober, Christine Pirker, Petra Vician, Christian R. Kowol, Rostyslav Stoika, Luca Salassa, Jürgen Rohr, Walter Berger
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-13 (2021)
Landomycins are promising anti-cancer agents with the potential to bypass common resistance pathways, but their mechanism of action remains incompletely understood. Here a mechanism is proposed involving intracellular sequential thiol-Michael and oxi
Externí odkaz:
https://doaj.org/article/bdb5050705c84bce940244077ea65781
Autor:
Tom Miclot, Cécilia Hognon, Emmanuelle Bignon, Alessio Terenzi, Stéphanie Grandemange, Giampaolo Barone, Antonio Monari
Publikováno v:
Molecules, Vol 27, Iss 10, p 3256 (2022)
DNA integrity is an important factor that assures genome stability and, more generally, the viability of cells and organisms. In the presence of DNA damage, the normal cell cycle is perturbed when cells activate their repair processes. Although effic
Externí odkaz:
https://doaj.org/article/9089be65808b4d6a930b4ad5a4b1b7c5
Autor:
Antonino Lauria, Gabriele La Monica, Alessio Terenzi, Giuseppe Mannino, Riccardo Bonsignore, Alessia Bono, Anna Maria Almerico, Giampaolo Barone, Carla Gentile, Annamaria Martorana
Publikováno v:
Molecules, Vol 26, Iss 14, p 4309 (2021)
Background: G-quadruplex (G4) forming sequences are recurrent in telomeres and promoter regions of several protooncogenes. In normal cells, the transient arrangements of DNA in G-tetrads may regulate replication, transcription, and translation proces
Externí odkaz:
https://doaj.org/article/998bf8f2183a4abd94326f12ef0f8db3
Autor:
Bernhard Englinger, Sebastian Kallus, Julia Senkiv, Daniela Heilos, Lisa Gabler, Sushilla van Schoonhoven, Alessio Terenzi, Patrick Moser, Christine Pirker, Gerald Timelthaler, Walter Jäger, Christian R. Kowol, Petra Heffeter, Michael Grusch, Walter Berger
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-13 (2017)
Abstract Background Studying the intracellular distribution of pharmacological agents, including anticancer compounds, is of central importance in biomedical research. It constitutes a prerequisite for a better understanding of the molecular mechanis
Externí odkaz:
https://doaj.org/article/ab5f3166b8d14e12903480ffb0754129
Autor:
Alessio Terenzi, Hugo Gattuso, Angelo Spinello, Bernhard K. Keppler, Christophe Chipot, François Dehez, Giampaolo Barone, Antonio Monari
Publikováno v:
Antioxidants, Vol 8, Iss 10, p 472 (2019)
The DNA-binding of the natural benzophenanthridine alkaloid chelerythrine (CHE) has been assessed by combining molecular modeling and optical absorption spectroscopy. Specifically, both double-helical (B-DNA) and G-quadruplex sequences—representati
Externí odkaz:
https://doaj.org/article/7432590f93124f6f88a5c1ada4d8c5f2
Autor:
Giovanni Salassa, Alessio Terenzi
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3483 (2019)
Oxadizoles are heterocyclic ring systems that find application in different scientific disciplines, from medicinal chemistry to optoelectronics. Coordination with metals (especially the transition ones) proved to enhance the intrinsic characteristics
Externí odkaz:
https://doaj.org/article/44c85c50151c4ea7a206df548dc947e4
Autor:
Emmanuelle Bignon, Angelo Spinello, Tom Miclot, Luisa D’Anna, Cosimo Ducani, Stéphanie Grandemange, Giampaolo Barone, Antonio Monari, Alessio Terenzi
Publikováno v:
The Journal of Physical Chemistry Letters. 14:4704-4710
Autor:
Angelo Spinello, Luisa D’Anna, Emmanuelle Bignon, Tom Miclot, Stéphanie Grandemange, Alessio Terenzi, Giampaolo Barone, Florent Barbault, Antonio Monari
The Transmembrane Protease Serine 2 (TMPRSS2) is a human enzyme which is involved in the maturation and post-translation of different proteins. In addition of being overexpressed in cancer cells, TMPRSS2 plays a further fundamental role in favoring v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ade9bac353b2f11d18e69c0c665df1
https://doi.org/10.1101/2023.04.23.537985
https://doi.org/10.1101/2023.04.23.537985
Autor:
Luisa D’Anna, Tom Miclot, Emmanuelle Bignon, Ugo Perricone, Giampaolo Barone, Antonio Monari, Alessio Terenzi
The genome of SARS-CoV-2 coronavirus is made up of a single-stranded RNA fragment that can assume a specific secondary structure, whose stability can influence the virus ability to reproduce. Recent studies have identified putative guanine quadruplex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e32878349baf5c5c17f44b75b5c93a9
https://doi.org/10.1101/2023.04.13.536758
https://doi.org/10.1101/2023.04.13.536758
Autor:
Luisa D'Anna, Simona Rubino, Candida Pipitone, Graziella Serio, Carla Gentile, Antonio Palumbo Piccionello, Francesco Giannici, Giampaolo Barone, Alessio Terenzi
DNA G-rich sequences can organize in four-stranded structures called G-quadruplexes (G4s). These motifs are enriched in significant sites within the human genomes, including telomeres and promoters of cancer related genes. For instance, KIT proto-onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3a1d21c858e584645e6aa44063cf94
https://hdl.handle.net/10447/584110
https://hdl.handle.net/10447/584110