Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alessio Reggio"'
Autor:
Francesca De Paolis, Stefano Testa, Gabriele Guarnaccia, Alessio Reggio, Ersilia Fornetti, Felice Cicciarelli, Rebecca Deodati, Sergio Bernardini, Daniele Peluso, Jacopo Baldi, Roberto Biagini, Flavia Cobianchi Bellisari, Antonio Izzo, Ferruccio Sgalambro, Francesco Arrigoni, Francesco Rizzo, Stefano Cannata, Tommaso Sciarra, Claudia Fuoco, Cesare Gargioli
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Volumetric Muscle Loss (VML), resulting from severe trauma or surgical ablation, is a pathological condition preventing myofibers regeneration, since skeletal muscle owns the remarkable ability to restore tissue damage, but only w
Externí odkaz:
https://doaj.org/article/fc75880615d64f81aeea01a04e288876
A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
Autor:
Alessio Reggio, Francesca De Paolis, Salma Bousselmi, Felice Cicciarelli, Sergio Bernardini, Alberto Rainer, Dror Seliktar, Stefano Testa, Carmine Cirillo, Paolo Grumati, Stefano Cannata, Claudia Fuoco, Cesare Gargioli
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/b35710252e3c49fd83b1ee9eb6a58db2
Autor:
Sandhya Chipurupalli, Raja Ganesan, Giulia Martini, Luigi Mele, Alessio Reggio, Marianna Esposito, Elango Kannan, Vigneshwaran Namasivayam, Paolo Grumati, Vincenzo Desiderio, Nirmal Robinson
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-13 (2022)
Abstract In the tumor microenvironment, cancer cells experience hypoxia resulting in the accumulation of misfolded/unfolded proteins largely in the endoplasmic reticulum (ER). Consequently, ER proteotoxicity elicits unfolded protein response (UPR) as
Externí odkaz:
https://doaj.org/article/6960be6ee9d6464ca00916b97db93904
Autor:
Giulio Giuliani, Simone Vumbaca, Claudia Fuoco, Cesare Gargioli, Ezio Giorda, Giorgia Massacci, Alessandro Palma, Alessio Reggio, Federica Riccio, Marco Rosina, Maria Vinci, Luisa Castagnoli, Gianni Cesareni
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-24 (2021)
Abstract The term micro-heterogeneity refers to non-genetic cell to cell variability observed in a bell-shaped distribution of the expression of a trait within a population. The contribution of micro-heterogeneity to physiology and pathology remains
Externí odkaz:
https://doaj.org/article/0ccf14b53959408ea9dfa6c7a33e6a4a
Autor:
Alessandro Palma, Andrea Cerquone Perpetuini, Federica Ferrentino, Claudia Fuoco, Cesare Gargioli, Giulio Giuliani, Marta Iannuccelli, Luana Licata, Elisa Micarelli, Serena Paoluzi, Livia Perfetto, Lucia Lisa Petrilli, Alessio Reggio, Marco Rosina, Francesca Sacco, Simone Vumbaca, Alessandro Zuccotti, Luisa Castagnoli, Gianni Cesareni
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell–cell interactions and/or p
Externí odkaz:
https://doaj.org/article/9f45e6fe14f34ec7aca1e27d5bd53a15
Autor:
Lucia Lisa Petrilli, Filomena Spada, Alessandro Palma, Alessio Reggio, Marco Rosina, Cesare Gargioli, Luisa Castagnoli, Claudia Fuoco, Gianni Cesareni
Publikováno v:
Cells, Vol 9, Iss 7, p 1723 (2020)
The interstitial space surrounding the skeletal muscle fibers is populated by a variety of mononuclear cell types. Upon acute or chronic insult, these cell populations become activated and initiate finely-orchestrated crosstalk that promotes myofiber
Externí odkaz:
https://doaj.org/article/8186bf711daa4bcd8794299f6680badc
Autor:
Jennifer Cable, Eilika Weber‐Ban, Tim Clausen, Kylie J. Walters, Michal Sharon, Daniel J. Finley, Yangnan Gu, John Hanna, Yue Feng, Sascha Martens, Anne Simonsen, Malene Hansen, Hong Zhang, Jonathan M. Goodwin, Alessio Reggio, Chunmei Chang, Liang Ge, Brenda A. Schulman, Raymond J. Deshaies, Ivan Dikic, J. Wade Harper, Ingrid E. Wertz, Nicolas H. Thomä, Mikołaj Słabicki, Judith Frydman, Ursula Jakob, Della C. David, Eric J. Bennett, Carolyn R. Bertozzi, Richa Sardana, Vinay V. Eapen, Serena Carra
Publikováno v:
Annals of the New York Academy of Sciences 1510(1), 79-99 (2022). doi:10.1111/nyas.14745
Targeted protein degradation is critical for proper cellular function and development. Protein degradation pathways, such as the ubiquitin proteasomes system, autophagy, and endosome-lysosome pathway, must be tightly regulated to ensure proper elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88110e83b56645cb723743deb2706a33
Autor:
Giorgia Di Lorenzo, Alessio Reggio, Carmine Cirillo, Elena Polishchuk, Adeela Hussain, Mariana Tellechea, Paolo Grumati, Alexandra Stolz, Marianna Esposito, Ivana Peluso, Antje K. Huebner, Christian A. Hübner, Viviana Buonomo, Carmine Settembre, Rayene Berkane, Ramachandra M. Bhaskara, Gerhard Hummer
Publikováno v:
EMBO Reports
EMBO reports
EMBO reports
Degradation of the endoplasmic reticulum (ER) via selective autophagy (ER‐phagy) is vital for cellular homeostasis. We identify FAM134A/RETREG2 and FAM134C/RETREG3 as ER‐phagy receptors, which predominantly exist in an inactive state under basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2ada37bbe88407d38b09df8710c82f
https://pubmed.ncbi.nlm.nih.gov/34338405
https://pubmed.ncbi.nlm.nih.gov/34338405
Autor:
Cesare Gargioli, Marco Rosina, Giorgia Massacci, Filomena Spada, Alessandro Zuccotti, Alessio Reggio, Claudia Fuoco, Luisa Castagnoli, Gianni Cesareni
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Fibro/Adipogenic Progenitors (FAPs) define a stem cell population playing a pro-regenerative role after muscle damage. When removed from their natural niche, FAPs readily differentiate into adipocytes or fibroblasts. This digressive differentiation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a139bc3489370afcf83c43e22726dba
http://link.springer.com/article/10.1038/s41598-019-39538-y
http://link.springer.com/article/10.1038/s41598-019-39538-y
Publikováno v:
The FEBS journalReferences. 289(21)
The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has contributed to modify the monocentric view of muscle regeneration beyond muscle satellite cells (MuSCs). Now, we are aware that each population of the muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4098ce126273eee7a57d96eb04d75af0
https://pubmed.ncbi.nlm.nih.gov/34143565
https://pubmed.ncbi.nlm.nih.gov/34143565