Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alessio Fabozzi"'
Autor:
Maria Chiara Scaini, Cristina Catoni, Cristina Poggiana, Jacopo Pigozzo, Luisa Piccin, Kevin Leone, Ilaria Scarabello, Antonella Facchinetti, Chiara Menin, Lisa Elefanti, Stefania Pellegrini, Valentina Aleotti, Riccardo Vidotto, Francesca Schiavi, Alessio Fabozzi, Vanna Chiarion-Sileni, Antonio Rosato
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract Melanoma heterogeneity is a hurdle in metastatic disease management. Although the advent of targeted therapy has significantly improved patient outcomes, the occurrence of resistance makes monitoring of the tumor genetic landscape mandatory.
Externí odkaz:
https://doaj.org/article/168759f0adb14fe5b0f672e54dd70bb5
Autor:
Giulia Pasello, Aline S. C. Fabricio, Paola Del Bianco, Valentina Salizzato, Adolfo Favaretto, Luisa Piccin, Fable Zustovich, Alessio Fabozzi, Costanza De Rossi, Jacopo Pigozzo, Mattia De Nuzzo, Elia Cappelletto, Laura Bonanno, Dario Palleschi, Gian Luca De Salvo, Valentina Guarneri, Massimo Gion, Vanna Chiarion-Sileni
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Immune Checkpoint Inhibitors (ICIs) lead to durable response and a significant increase in long-term survival in patients with advanced malignant melanoma (MM) and Non-Small Cell Lung Cancer (NSCLC). The identification of serum cy
Externí odkaz:
https://doaj.org/article/eaa29a66434e4108acd2e04152a4052d
Autor:
Anna Tosi, Rocco Cappellesso, Angelo Paolo Dei Tos, Valentina Rossi, Camillo Aliberti, Jacopo Pigozzo, Alessio Fabozzi, Marta Sbaraglia, Stella Blandamura, Paola Del Bianco, Vanna Chiarion-Sileni, Antonio Rosato
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Uveal melanoma (UM) represents the most common primary intra-ocular malignancy in adults. Up to 50% of the patients develop distant metastases within 10 years from diagnosis, with the liver as the most common site. Upon metastatiz
Externí odkaz:
https://doaj.org/article/0c9b6af792964d629891bcec8fb528bc
Autor:
Marco Rastrelli, Paolo Del Fiore, Irene Russo, Jacopo Tartaglia, Alessandro Dal Monico, Rocco Cappellesso, Lorenzo Nicolè, Luisa Piccin, Alessio Fabozzi, Bernardo Biffoli, Claudia Di Prata, Beatrice Ferrazzi, Luigi Dall’Olmo, Antonella Vecchiato, Romina Spina, Francesco Russano, Elisabetta Bezzon, Sara Cingarlini, Renzo Mazzarotto, Alessandro Parisi, Giovanni Scarzello, Jacopo Pigozzo, Tito Brambullo, Saveria Tropea, Vincenzo Vindigni, Franco Bassetto, Daniele Bertin, Michele Gregianin, Angelo Paolo Dei Tos, Francesco Cavallin, Mauro Alaibac, Vanna Chiarion-Sileni, Simone Mocellin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundMerkel cell carcinoma (MCC) is a rare neuroendocrine tumor of the skin. The incidence of the disease has undergone a significant increase in recent years, which is caused by an increase in the average age of the population and in the use of
Externí odkaz:
https://doaj.org/article/ba1abd87bd5a4e5dba2984a6ed68da48
Autor:
Luigi Marano, Marianna Petrillo, Modestino Pezzella, Alberto Patriti, Bartolomeo Braccio, Giuseppe Esposito, Michele Grassia, Angela Romano, Francesco Torelli, Raffaele De Luca, Alessio Fabozzi, Giuseppe Falco, Natale Di Martino
Publikováno v:
Journal of Investigative Surgery, Vol 30, Iss 3, Pp 210-216 (2017)
Background: The extension of lymphadenectomy for surgical treatment of gastric cancer remains discordant among European and Japanese surgeons. Kinami et al. (Kinami S, Fujimura T, Ojima E, et al. PTD classification: proposal for a new classification
Externí odkaz:
https://doaj.org/article/cd9455b8cf694a5dbf76c4da8e050969
Autor:
Chiara Menin, Arcangela De Nicolo, Vanna Chiarion-Sileni, Maria Cristina Montesco, Simone Mocellin, Jacopo Pigozzo, Alessio Fabozzi, Antonio Sommariva, Paola Del Bianco, Tiziana Zanin, Lisa Elefanti, Carolina Zamuner, Camilla Stagni
Metastatic melanoma is characterized by complex genomic alterations, including a high rate of mutations in driver genes and widespread deletions and amplifications encompassing various chromosome regions. Among them, chromosome 7 is frequently gained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c10bbe711c47f45d010194b118f49d11
https://doi.org/10.1158/1535-7163.c.6537814.v1
https://doi.org/10.1158/1535-7163.c.6537814.v1
Autor:
Floriana Morgillo, Fortunato Ciardiello, Roberto Bianco, Mario Santini, Giancarlo Troncone, Teresa Troiani, Erika Martinelli, Federica Papaccio, Morena Fasano, Alfonso Fiorelli, Alessio Fabozzi, Marina Accardo, Umberto Malapelle, Donata Vitagliano, Giovanni Vicidomini, Claudio Bellevicine, Carminia Maria Della Corte
Purpose: Resistance to tyrosine kinase inhibitors (TKI) of EGF receptor (EGFR) is often related to activation of other signaling pathways and evolution through a mesenchymal phenotype.Experimental Design: Because the Hedgehog (Hh) pathway has emerged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf2e5e55bf434befdb503013212805e
https://doi.org/10.1158/1078-0432.c.6524682.v1
https://doi.org/10.1158/1078-0432.c.6524682.v1
Autor:
Floriana Morgillo, Fortunato Ciardiello, Roberto Bianco, Mario Santini, Giancarlo Troncone, Teresa Troiani, Erika Martinelli, Federica Papaccio, Morena Fasano, Alfonso Fiorelli, Alessio Fabozzi, Marina Accardo, Umberto Malapelle, Donata Vitagliano, Giovanni Vicidomini, Claudio Bellevicine, Carminia Maria Della Corte
Graphycal representation of the interplay between Hedgehog and MET pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e79f4d9c7f77449b6aa93cd0d867d9
https://doi.org/10.1158/1078-0432.22461057.v1
https://doi.org/10.1158/1078-0432.22461057.v1
Autor:
Floriana Morgillo, Fortunato Ciardiello, Roberto Bianco, Mario Santini, Giancarlo Troncone, Teresa Troiani, Erika Martinelli, Federica Papaccio, Morena Fasano, Alfonso Fiorelli, Alessio Fabozzi, Marina Accardo, Umberto Malapelle, Donata Vitagliano, Giovanni Vicidomini, Claudio Bellevicine, Carminia Maria Della Corte
Supplemental matherial and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e00f86a75c651c14e2bad8ddd0bd00
https://doi.org/10.1158/1078-0432.22461051.v1
https://doi.org/10.1158/1078-0432.22461051.v1
Autor:
Floriana Morgillo, Fortunato Ciardiello, Roberto Bianco, Mario Santini, Giancarlo Troncone, Teresa Troiani, Erika Martinelli, Federica Papaccio, Morena Fasano, Alfonso Fiorelli, Alessio Fabozzi, Marina Accardo, Umberto Malapelle, Donata Vitagliano, Giovanni Vicidomini, Claudio Bellevicine, Carminia Maria Della Corte
A) GLI1 promoter activity in EGFR-WT NSCLC cell lines. Effects of Hh and EGFR inhibition in EGFR-WT NSCLC cell lines on their abilities to B) growth, C) invade , D)migrate and E) colony forming. F)In vivo efficacy of erlotinib and LDE225 on EGFR-WT N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef12a28aab1847ccbaa49fae48590f
https://doi.org/10.1158/1078-0432.22461060.v1
https://doi.org/10.1158/1078-0432.22461060.v1